(Q35708009)

9 August 2017

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title

Unique function of the Nrf2-Keap1 pathway in the inducible expression of antioxidant and detoxifying enzymes (English)

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9 August 2017

Akira Kobayashi

1

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9 August 2017

Tsutomu Ohta

series ordinal

2

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9 August 2017

Masayuki Yamamoto

series ordinal

3

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9 August 2017

language of work or name

English

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publication date

1 January 2004

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9 August 2017

Methods in Enzymology

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9 August 2017

378

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9 August 2017

273-286

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Xenobiotic-inducible expression of murine glutathione S-transferase Ya subunit gene is controlled by an electrophile-responsive element

9 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE)

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Constitutive and beta-naphthoflavone-induced expression of the human gamma-glutamylcysteine synthetase heavy subunit gene is regulated by a distal antioxidant response element/TRE sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Cloning of Nrf1, an NF-E2-related transcription factor, by genetic selection in yeast

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Cloning and characterization of a novel erythroid cell-derived CNC family transcription factor heterodimerizing with the small Maf family proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Molecular cloning and functional characterization of a new Cap'n' collar family transcription factor Nrf3

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Accelerated DNA adduct formation in the lung of the Nrf2 knockout mouse exposed to diesel exhaust

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

kelch encodes a component of intercellular bridges in Drosophila egg chambers

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Cytoskeletal functions during Drosophila oogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Functional studies of the BTB domain in the Drosophila GAGA and Mod(mdg4) proteins.

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Multivalent DNA Binding Complex Generated by Small Maf and Bach1 as a Possible Biochemical Basis for β-Globin Locus Control Region Complex

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Long range interaction of cis-DNA elements mediated by architectural transcription factor Bach1

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Crystal structure of the BTB domain from PLZF

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Crystal structure of a free radical enzyme, galactose oxidase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

The kelch repeat superfamily of proteins: propellers of cell function

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Keap1 regulates both cytoplasmic-nuclear shuttling and degradation of Nrf2 in response to electrophiles

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Inhibition of the 26S proteasome induces expression of GLCLC, the catalytic subunit for gamma-glutamylcysteine synthetase

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Regulatory mechanisms of cellular response to oxidative stress

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Keap1-null mutation leads to postnatal lethality due to constitutive Nrf2 activation

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

pEF-BOS, a powerful mammalian expression vector

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

Antioxidant-inducible genes

1 reference

https://api.crossref.org/works/10.1016%2FS0076-6879%2804%2978021-0

7 January 2021

10.1016/S0076-6879(04)78021-0

Identifiers

DOI

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9 August 2017

1 reference