(Q35717366)

English

The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb

scientific article published on 28 December 2011

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

The Alzheimer's β-secretase enzyme BACE1 is required for accurate axon guidance of olfactory sensory neurons and normal glomerulus formation in the olfactory bulb (English)

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Alzheimer's disease

0 references

1 reference

based on heuristic

inferred from title

William A Eimer

0 references

author name string

Tharinda W Rajapaksha

1

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

William A Eimer

2

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Thomas C Bozza

3

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Robert Vassar

4

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

publication date

28 December 2011

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Molecular Neurodegeneration

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

6

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

88

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

https://scigraph.springernature.com/pub.10.1186/1750-1326-6-88

0 references

Identification of BACE1 cleavage sites in human voltage-gated sodium channel beta 2 subunit

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Neural Map Formation in the Mouse Olfactory System

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

BACE1 deficiency causes altered neuronal activity and neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Identification of beta-secretase (BACE1) substrates using quantitative proteomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

The beta-secretase enzyme BACE in health and Alzheimer's disease: regulation, cell biology, function, and therapeutic potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

BACE1 regulates voltage-gated sodium channels and neuronal activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

BACE1, a major determinant of selective vulnerability of the brain to amyloid-beta amyloidogenesis, is essential for cognitive, emotional, and synaptic functions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Structure and emergence of specific olfactory glomeruli in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

BACE knockout mice are healthy despite lacking the primary beta-secretase activity in brain: implications for Alzheimer's disease therapeutics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Identification of a Novel Aspartic Protease (Asp 2) as β-Secretase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Purification and cloning of amyloid precursor protein beta-secretase from human brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Mice deficient in G(olf) are anosmic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Visualizing an olfactory sensory map

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Spatial segregation of odorant receptor expression in the mammalian olfactory epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Topographic organization of sensory projections to the olfactory bulb

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

A zonal organization of odorant receptor gene expression in the olfactory epithelium

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

A novel multigene family may encode odorant receptors: a molecular basis for odor recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3269394

27 July 2018

BACE1 deficiency rescues memory deficits and cholinergic dysfunction in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-88

21 January 2018

Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-88

21 January 2018

Control of peripheral nerve myelination by the beta-secretase BACE1

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-88

21 January 2018

Bace1 modulates myelination in the central and peripheral nervous system.

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-88

21 January 2018

Beta-site amyloid precursor protein cleaving enzyme 1 levels become elevated in neurons around amyloid plaques: implications for Alzheimer's disease pathogenesis

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-88

21 January 2018

beta-Secretase expression in normal and functionally deprived rat olfactory bulbs: inverse correlation with oxidative metabolic activity.

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-88

21 January 2018

Phenotypic and biochemical analyses of BACE1- and BACE2-deficient mice

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-88

21 January 2018

Formation of precise connections in the olfactory bulb occurs in the absence of odorant-evoked neuronal activity

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-88

21 January 2018

Peripheral olfactory projections are differentially affected in mice deficient in a cyclic nucleotide-gated channel subunit

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-88

21 January 2018

Disruption of the type III adenylyl cyclase gene leads to peripheral and behavioral anosmia in transgenic mice

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-88

21 January 2018

Unilateral odor deprivation: differential effects due to time of treatment.

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-88

21 January 2018

Minigenes impart odorant receptor-specific axon guidance in the olfactory bulb

1 reference

https://api.crossref.org/works/10.1186%2F1750-1326-6-88

21 January 2018

Identifiers

10.1186/1750-1326-6-88

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

Dimensions Publication ID

0 references

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

9 August 2017

ResearchGate publication ID

0 references

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