(Q35727498)

9 August 2017

title

Transcriptional regulation of β-secretase-1 by 12/15-lipoxygenase results in enhanced amyloidogenesis and cognitive impairments (English)

1 reference

9 August 2017

main subject

cognitive dysfunction

1 reference

Jin Chu

1

1 reference

9 August 2017

Jia-Min Zhuo

series ordinal

2

1 reference

9 August 2017

Domenico Praticò

series ordinal

3

1 reference

9 August 2017

publication date

1 January 2012

1 reference

9 August 2017

1 reference

9 August 2017

volume

71

1 reference

9 August 2017

issue

1

1 reference

9 August 2017

page(s)

57-67

1 reference

5-lipoxygenase as an endogenous modulator of amyloid β formation in vivo

9 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Involvement of 5-lipoxygenase in the corticosteroid-dependent amyloid beta formation: in vitro and in vivo evidence

27 July 2018

1 reference

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Amelioration of the Alzheimer's disease phenotype by absence of 12/15-lipoxygenase

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Normalization of hyperhomocysteinemia improves cognitive deficits and ameliorates brain amyloidosis of a transgenic mouse model of Alzheimer's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Acceleration of brain amyloidosis in an Alzheimer's disease mouse model by a folate, vitamin B6 and B12-deficient diet

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Function, regulation and therapeutic properties of beta-secretase (BACE1).

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

5-Lipoxygenase gene disruption reduces amyloid-beta pathology in a mouse model of Alzheimer's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

A role for 12/15 lipoxygenase in the amyloid beta precursor protein metabolism

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Transcriptional and translational regulation of BACE1 expression--implications for Alzheimer's disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Absence of 12/15 lipoxygenase reduces brain oxidative stress in apolipoprotein E-deficient mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Structural biology of mammalian lipoxygenases: enzymatic consequences of targeted alterations of the protein structure.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Specificity of transcriptional regulation by the zinc finger transcription factors Sp1, Sp3, and Egr-1.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

12/15-lipoxygenase is increased in Alzheimer's disease: possible involvement in brain oxidative stress

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Blockade of 12-lipoxygenase expression protects cortical neurons from apoptosis induced by beta-amyloid peptide

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

12/15-Lipoxygenase activity mediates inflammatory monocyte/endothelial interactions and atherosclerosis in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Lipoxygenases: occurrence, functions, catalysis, and acquisition of substrate

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

A role for 12-lipoxygenase in nerve cell death caused by glutathione depletion.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Mithramycin inhibits SP1 binding and selectively inhibits transcriptional activity of the dihydrofolate reductase gene in vitro and in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Elevation of 12/15 lipoxygenase products in AD and mild cognitive impairment

27 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FANA.22625

Impaired Pavlovian cued fear conditioning in Tg2576 mice expressing a human mutant amyloid precursor protein gene.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FANA.22625

A conformational constraint improves a beta-secretase inhibitor but for an unexpected reason.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1002%2FANA.22625

12-lipoxygenase metabolites of arachidonic acid mediate metabotropic glutamate receptor-dependent long-term depression at hippocampal CA3-CA1 synapses.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3270901

25 September 2018

Identifiers

DOI

10.1002/ANA.22625

1 reference

9 August 2017

1 reference

9 August 2017

1 reference