(Q35729242)

9 August 2017

title

Biodistribution and pharmacokinetics of colon-specific HPMA copolymer--9-aminocamptothecin conjugate in mice (English)

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9 August 2017

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Song-Qi Gao

1

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9 August 2017

Zheng-Rong Lu

series ordinal

2

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9 August 2017

Pavla Kopecková

series ordinal

3

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9 August 2017

Jindrich Kopecek

series ordinal

4

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9 August 2017

language of work or name

English

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publication date

27 October 2006

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Journal of Controlled Release

9 August 2017

published in

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9 August 2017

volume

117

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9 August 2017

issue

2

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9 August 2017

page(s)

179-185

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Pharmacokinetic and pharmacodynamic evaluation of a novel in situ forming poly(ethylene glycol)-based hydrogel for the controlled delivery of the camptothecins

9 August 2017

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1 reference

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12 July 2018

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Relation between 9-aminocamptothecin systemic exposure and tumor response in human solid tumor xenografts.

12 July 2018

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Phase I and pharmacologic study of oral (PEG-1000) 9-aminocamptothecin in adult patients with solid tumors

12 July 2018

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A phase I and pharmacokinetic study of a new camptothecin derivative, 9-aminocamptothecin.

12 July 2018

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Increased 9-aminocamptothecin dose requirements in patients on anticonvulsants. NABTT CNS Consortium. The New Approaches to Brain Tumor Therapy

12 July 2018

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12 July 2018

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Use of azo polymers for colon-specific drug delivery

12 July 2018

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12 July 2018

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9-Aminocamptothecin and beyond. Preclinical and clinical studies

12 July 2018

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Topoisomerase I and II activity in human breast, cervix, lung and colon cancer

12 July 2018

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12 July 2018

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Identification of mammalian DNA topoisomerase I as an intracellular target of the anticancer drug camptothecin

12 July 2018

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A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues

12 July 2018

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Mechanism of the reaction catalyzed by the DNA untwisting enzyme: Attachment of the enzyme to 3′-terminus of the nicked DNA

12 July 2018

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Oral bioavailability of a low molecular weight heparin using a polymeric delivery system

12 July 2018

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Colon-specific 9-aminocamptothecin-HPMA copolymer conjugates containing a 1,6-elimination spacer

25 September 2018

1 reference

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A pH-sensitive microsphere system for the colon delivery of tacrolimus containing nanoparticles

25 September 2018

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Phase I and pharmacological study of oral 9-aminocamptothecin colloidal dispersion (NSC 603071) in patients with advanced solid tumors

25 September 2018

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Biorecognizable HPMA copolymer-drug conjugates for colon-specific delivery of 9-aminocamptothecin

25 September 2018

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Why drugs fail: of mice and men revisited

25 September 2018

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Pharmacokinetics of the 9-amino and 10,11-methylenedioxy derivatives of camptothecin in mice.

25 September 2018

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Synthesis of bioadhesive lectin-HPMA copolymer-cyclosporin conjugates

25 September 2018

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12 December 2020

Biorecognition of HPMA copolymer-lectin conjugates as an indicator of differentiation of cell-surface glycoproteins in development, maturation, and diseases of human and rodent gastrointestinal tissues

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12 December 2020

Pharmacokinetics of orally administered camptothecins

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12 December 2020

FURTHER FACTORS AFFECTING THE HYDROXYLATION OF ANILINE AND SOME OF ITS DERIVATIVES BY LIVER MICROSOMES

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12 December 2020

Phase I clinical and pharmacokinetic study of oral 9-aminocamptothecin (NSC-603071)

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12 December 2020

Differential toxicity of camptothecin, topotecan and 9-aminocamptothecin to human, canine, and murine myeloid progenitors (CFU-GM) in vitro

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12 December 2020

Phase I and pharmacologic study of 9-aminocamptothecin given by 72-hour infusion in adult cancer patients

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12 December 2020

Plant antitumor agents. 22. Isolation of 11-hydroxycamptothecin from Camptotheca acuminata Decne: total synthesis and biological activity

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12 December 2020

A new approach to the oral administration of insulin and other peptide drugs

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12 December 2020

Plant antitumor agents. 25. Total synthesis and antileukemic activity of ring A substituted camptothecin analogues. Structure-activity correlations

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12 December 2020

DNA topoisomerase I--targeted chemotherapy of human colon cancer in xenografts

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12 December 2020

The involvement of active DNA synthesis in camptothecin-induced G2 arrest: altered regulation of p34cdc2/cyclin B

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12 December 2020

Complete inhibition of growth followed by death of human malignant melanoma cells in vitro and regression of human melanoma xenografts in immunodeficient mice induced by camptothecins

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12 December 2020

Camptothecin derivatives induce regression of human ovarian carcinomas grown in nude mice and distinguish between non-tumorigenic and tumorigenic cells in vitro

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12 December 2020

Interaction between replication forks and topoisomerase I-DNA cleavable complexes: studies in a cell-free SV40 DNA replication system

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12 December 2020

Analysis of the active lactone form of 9-aminocamptothecin in plasma using solid-phase extraction and high-performance liquid chromatography

1 reference

12 December 2020

10.1016/J.JCONREL.2006.10.024

Identifiers

DOI

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9 August 2017

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9 August 2017

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