(Q35733326)

10 August 2017

title

The second extracellular loop of the dopamine D2 receptor lines the binding-site crevice (English)

1 reference

10 August 2017

Lei Shi

1

1 reference

10 August 2017

Jonathan A Javitch

series ordinal

2

1 reference

10 August 2017

language of work or name

English

0 references

publication date

2 January 2004

1 reference

Proceedings of the National Academy of Sciences of the United States of America

10 August 2017

published in

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10 August 2017

volume

101

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10 August 2017

issue

2

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10 August 2017

page(s)

440-445

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Organization of the G protein-coupled receptors rhodopsin and opsin in native membranes

10 August 2017

cites work

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A single subunit (GB2) is required for G-protein activation by the heterodimeric GABA(B) receptor

12 July 2018

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12 July 2018

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The first transmembrane segment of the dopamine D2 receptor: accessibility in the binding-site crevice and position in the transmembrane bundle

12 July 2018

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12 July 2018

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Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors

12 July 2018

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Modeling of loops in protein structures

12 July 2018

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The fourth transmembrane segment of the dopamine D2 receptor: accessibility in the binding-site crevice and position in the transmembrane bundle

12 July 2018

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Coupling of canine serotonin 5-HT(1B) and 5-HT(1D) receptor subtypes to the formation of inositol phosphates by dual interactions with endogenous G(i/o) and recombinant G(alpha15) proteins.

12 July 2018

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Crystal structure of rhodopsin: A G protein-coupled receptor

12 July 2018

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Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

12 July 2018

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Electrostatic and aromatic microdomains within the binding-site crevice of the D2 receptor: contributions of the second membrane-spanning segment.

12 July 2018

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Chimeric receptor analysis of the ketanserin binding site in the human 5-Hydroxytryptamine1D receptor: importance of the second extracellular loop and fifth transmembrane domain in antagonist binding

12 July 2018

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State-dependent accessibility and electrostatic potential in the channel of the acetylcholine receptor. Inferences from rates of reaction of thiosulfonates with substituted cysteines in the M2 segment of the alpha subunit

12 July 2018

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Ligand stabilization of the beta 2 adrenergic receptor: effect of DTT on receptor conformation monitored by circular dichroism and fluorescence spectroscopy

12 July 2018

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Residues in the seventh membrane-spanning segment of the dopamine D2 receptor accessible in the binding-site crevice.

12 July 2018

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Bicistronic vector for the creation of stable mammalian cell lines that predisposes all antibiotic-resistant cells to express recombinant protein.

12 July 2018

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Glutamate residues in the second extracellular loop of the human A2a adenosine receptor are required for ligand recognition

12 July 2018

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Comparative protein modelling by satisfaction of spatial restraints

12 July 2018

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A cysteine residue in the third membrane-spanning segment of the human D2 dopamine receptor is exposed in the binding-site crevice.

12 July 2018

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Role of the second extracellular loop of adenosine receptors in agonist and antagonist binding. Analysis of chimeric A1/A3 adenosine receptors

12 July 2018

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Mapping the binding-site crevice of the dopamine D2 receptor by the substituted-cysteine accessibility method

12 July 2018

1 reference

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

12 July 2018

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Reactivity of small thiolate anions and cysteine-25 in papain toward methyl methanethiosulfonate

12 July 2018

1 reference

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Structure. Rhodopsin sees the light

12 July 2018

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https://api.crossref.org/works/10.1073%2FPNAS.2237265100

Preservation and staining of myelinated nerve fibers.

21 January 2018

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Design, synthesis and pharmacological evaluation of 5-hydroxytryptamine(1a) receptor ligands to explore the three-dimensional structure of the receptor.

21 January 2018

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Key issues in the computational simulation of GPCR function: representation of loop domains.

21 January 2018

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Residues in the fifth membrane-spanning segment of the dopamine D2 receptor exposed in the binding-site crevice.

21 January 2018

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https://api.crossref.org/works/10.1073%2FPNAS.2237265100

The fourth transmembrane segment forms the interface of the dopamine D2 receptor homodimer.

21 January 2018

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From agonist to antagonist: Fab fragments of an agonist-like monoclonal anti-beta(2)-adrenoceptor antibody behave as antagonists

21 January 2018

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Mapping the agonist binding site of the GABAA receptor: evidence for a beta-strand.

25 September 2018

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Conserved extracellular cysteine pair in the M3 muscarinic acetylcholine receptor is essential for proper receptor cell surface localization but not for G protein coupling

25 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2237265100

Electrostatic potential of the acetylcholine binding sites in the nicotinic receptor probed by reactions of binding-site cysteines with charged methanethiosulfonates

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2237265100

A cluster of aromatic residues in the sixth membrane-spanning segment of the dopamine D2 receptor is accessible in the binding-site crevice

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.2237265100

Site-directed mutagenesis of the rat m1 muscarinic acetylcholine receptor. Role of conserved cysteines in receptor function

21 January 2018

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12 December 2020

The high affinity state of the beta 2-adrenergic receptor requires unique interaction between conserved and non-conserved extracellular loop cysteines

1 reference

12 December 2020

Substituted-cysteine accessibility method

1 reference

12 December 2020

Identification of critical extracellular loop residues involved in alpha 1-adrenergic receptor subtype-selective antagonist binding

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.2237265100

1 reference

10 August 2017

0 references

1 reference

10 August 2017

1 reference