(Q35740098)

10 August 2017

title

G9a is essential for EMT-mediated metastasis and maintenance of cancer stem cell-like characters in head and neck squamous cell carcinoma (English)

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10 August 2017

main subject

neoplastic stem cells

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head and neck squamous cell carcinoma

inferred from title

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Shuli Liu

1

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10 August 2017

Dongxia Ye

2

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10 August 2017

Wenzheng Guo

3

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10 August 2017

Wenwen Yu

4

1 reference

10 August 2017

Yue He

5

1 reference

10 August 2017

Jingzhou Hu

6

1 reference

10 August 2017

Yanan Wang

7

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10 August 2017

Ling Zhang

8

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10 August 2017

Yueling Liao

9

1 reference

10 August 2017

Hongyong Song

10

1 reference

10 August 2017

Shuangshuang Zhong

11

1 reference

10 August 2017

Dongliang Xu

12

1 reference

10 August 2017

Huijing Yin

13

1 reference

10 August 2017

Beibei Sun

14

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10 August 2017

Xiaofei Wang

15

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10 August 2017

Jingyi Liu

16

1 reference

10 August 2017

Yadi Wu

17

1 reference

10 August 2017

Binhua P Zhou

18

1 reference

10 August 2017

Zhiyuan Zhang

19

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10 August 2017

Jiong Deng

20

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10 August 2017

language of work or name

English

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publication date

1 March 2015

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10 August 2017

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10 August 2017

volume

6

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10 August 2017

issue

9

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10 August 2017

page(s)

6887-6901

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The H3K9 methyltransferase G9a is a marker of aggressive ovarian cancer that promotes peritoneal metastasis.

10 August 2017

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Inhibition of G9a induces DUSP4-dependent autophagic cell death in head and neck squamous cell carcinoma.

12 July 2018

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The methyltransferase G9a regulates HoxA9-dependent transcription in AML.

12 July 2018

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The histone H3 methyltransferase G9A epigenetically activates the serine-glycine synthesis pathway to sustain cancer cell survival and proliferation

12 July 2018

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Repression of G protein-coupled receptor family C group 5 member A is associated with pathologic differentiation grade of oral squamous cell carcinoma

12 July 2018

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G9a, a multipotent regulator of gene expression

12 July 2018

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12 July 2018

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12 July 2018

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12 July 2018

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G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancer

12 July 2018

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Recruitment of coregulator G9a by Runx2 for selective enhancement or suppression of transcription

12 July 2018

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12 July 2018

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12 July 2018

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Snail as a novel marker for regional metastasis in head and neck squamous cell carcinoma

12 July 2018

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Enhancive effects of Lewis y antigen on CD44-mediated adhesion and spreading of human ovarian cancer cell line RMG-I.

12 July 2018

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Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters

12 July 2018

1 reference

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The molecular biology of head and neck cancer

12 July 2018

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H3K9 histone methyltransferase G9a promotes lung cancer invasion and metastasis by silencing the cell adhesion molecule Ep-CAM.

12 July 2018

1 reference

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Bmi1 is essential in Twist1-induced epithelial-mesenchymal transition

12 July 2018

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12 July 2018

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Inflammation and EMT: an alliance towards organ fibrosis and cancer progression

12 July 2018

1 reference

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Epithelial-mesenchymal transitions in development and disease

12 July 2018

1 reference

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The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs

12 July 2018

1 reference

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Histones: annotating chromatin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Dual role for the methyltransferase G9a in the maintenance of beta-globin gene transcription in adult erythroid cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Inflammation: a driving force speeds cancer metastasis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

The NF-kappaB factor RelB and histone H3 lysine methyltransferase G9a directly interact to generate epigenetic silencing in endotoxin tolerance

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Snail and slug mediate radioresistance and chemoresistance by antagonizing p53-mediated apoptosis and acquiring a stem-like phenotype in ovarian cancer cells

12 July 2018

1 reference

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The basics of epithelial-mesenchymal transition

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Stabilization of snail by NF-kappaB is required for inflammation-induced cell migration and invasion

12 July 2018

1 reference

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Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells

12 July 2018

1 reference

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Cancer stem cells in solid tumours: accumulating evidence and unresolved questions

12 July 2018

1 reference

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The epithelial-mesenchymal transition generates cells with properties of stem cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Downregulation of histone H3 lysine 9 methyltransferase G9a induces centrosome disruption and chromosome instability in cancer cells.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Pre-EMTing metastasis? Recapitulation of morphogenetic processes in cancer.

12 July 2018

1 reference

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Histone lysine demethylases: emerging roles in development, physiology and disease

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Hypoxic stress induces dimethylated histone H3 lysine 9 through histone methyltransferase G9a in mammalian cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

New signals from the invasive front

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Histone H3 lysine 9 methyltransferase G9a is a transcriptional coactivator for nuclear receptors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Gfi1 coordinates epigenetic repression of p21Cip/WAF1 by recruitment of histone lysine methyltransferase G9a and histone deacetylase 1

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

The transcription factor snail induces tumor cell invasion through modulation of the epithelial cell differentiation program.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Invasion and metastasis of oral cancer cells require methylation of E-cadherin and/or degradation of membranous beta-catenin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

CCAAT displacement protein/cut homolog recruits G9a histone lysine methyltransferase to repress transcription

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Localized domains of G9a-mediated histone methylation are required for silencing of neuronal genes

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Dissecting the metastatic cascade

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

The two faces of transforming growth factor beta in carcinogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

The snail superfamily of zinc-finger transcription factors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Establishment and characterization of nine new head and neck cancer cell lines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Recurrence at the primary site in head and neck cancer and the significance of neck lymph node metastases as a prognostic factor

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

TGF-beta induced transdifferentiation of mammary epithelial cells to mesenchymal cells: involvement of type I receptors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Nodal metastases and prognosis in carcinoma of the oral cavity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

TWIST1 and SNAI1 as markers of poor prognosis in human colorectal cancer are associated with the expression of ALDH1 and TGF-β1.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Changes in immunoexpression of E-cadherin and beta-catenin in oral squamous cell carcinoma with and without nodal metastasis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Identification of a gene expression signature associated with recurrent disease in squamous cell carcinoma of the head and neck

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Prognostic factors for survival and tumor control in cervical lymph node metastases from head and neck cancer. A multivariate study of 492 cases

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4466657

Cancer stem cells in squamous cell carcinoma switch between two distinct phenotypes that are preferentially migratory or proliferative

23 October 2018

1 reference

12 December 2020

Identification of genes associated with tumorigenesis and metastatic potential of hypopharyngeal cancer by microarray analysis

1 reference

12 December 2020

An expression profile for diagnosis of lymph node metastases from primary head and neck squamous cell carcinomas

1 reference

12 December 2020

Reduced E-cadherin expression is an indicator of unfavourable prognosis in oral squamous cell carcinoma

1 reference

12 December 2020

Identifiers

DOI

10.18632/ONCOTARGET.3159

0 references

PMC publication ID

4466657

1 reference

10 August 2017

1 reference