(Q35745568)

10 August 2017

title

Depletion of hepatic glutathione prevents death receptor-dependent apoptotic and necrotic liver injury in mice (English)

1 reference

10 August 2017

0 references

1 reference

H Hentze

1

1 reference

10 August 2017

F Gantner

series ordinal

2

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10 August 2017

S A Kolb

series ordinal

3

1 reference

10 August 2017

A Wendel

series ordinal

4

1 reference

10 August 2017

language of work or name

English

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publication date

1 June 2000

1 reference

The American Journal of Pathology

10 August 2017

published in

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10 August 2017

volume

156

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10 August 2017

issue

6

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10 August 2017

page(s)

2045-2056

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Altered migration of gut-derived T lymphocytes after activation with concanavalin A.

10 August 2017

cites work

1 reference

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Overexpression of gamma-glutamylcysteine synthetase suppresses tumor necrosis factor-induced apoptosis and activation of nuclear transcription factor-kappa B and activator protein-1

27 July 2018

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CD95-Mediated murine hepatic apoptosis requires an intact glutathione status

27 July 2018

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Review: The role of glutathione in the regulation of apoptosis

27 July 2018

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27 July 2018

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Mitochondria and apoptosis

27 July 2018

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Redox regulation of apoptotic cell death

27 July 2018

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Glutathione levels determine apoptosis in macrophages

27 July 2018

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Fas-mediated apoptosis in mouse hepatocytes involves the processing and activation of caspases

27 July 2018

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Dysregulation of apoptosis as a mechanism of liver disease: an overview.

27 July 2018

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Concanavalin A-induced liver injury triggers hepatocyte proliferation

27 July 2018

1 reference

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Rescue of cells from apoptosis by inhibition of active GSH extrusion.

27 July 2018

1 reference

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Mechanisms of liver damage

27 July 2018

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Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

27 July 2018

1 reference

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Pathological spectrum of alcoholic liver disease

27 July 2018

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T cell stimulus-induced crosstalk between lymphocytes and liver macrophages results in augmented cytokine release

27 July 2018

1 reference

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The 55-kD tumor necrosis factor receptor and CD95 independently signal murine hepatocyte apoptosis and subsequent liver failure

27 July 2018

1 reference

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Glutathione and glutathione delivery compounds

27 July 2018

1 reference

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The inflammatory cytokines. New developments in the pathophysiology and treatment of septic shock

27 July 2018

1 reference

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DNA fragmentation in mouse organs during endotoxic shock

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Role of sinusoidal endothelial cells of the liver in concanavalin A-induced hepatic injury in mice

27 July 2018

1 reference

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Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection

27 July 2018

1 reference

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T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Hepatic and metabolic effects of ethanol: pathogenesis and prevention

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Modulation of transcription factor NF kappa B activity by intracellular glutathione levels and by variations of the extracellular cysteine supply

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

In situ detection of fragmented dna (tunel assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: A cautionary note

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Tumor necrosis factor-induced hepatocyte apoptosis precedes liver failure in experimental murine shock models.

27 July 2018

1 reference

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Chemical depletion of glutathione in vivo

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Alcohol ingestion, liver glutathione and lipoperoxidation: metabolic interrelations and pathological implications

27 July 2018

1 reference

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Acetaminophen-induced hepatic necrosis. IV. Protective role of glutathione

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Decreased hepatic glutathione levels in septic shock. Predisposition of hepatocytes to oxidative stress: an experimental approach.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Cellular defense mechanisms against toxic substances

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Measurement of in vivo lipid peroxidation and toxicological significance

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

27 July 2018

1 reference

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Nonxenobiotic manipulation and sulfur precursor specificity of human endothelial cell glutathione

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

A T cell-dependent experimental liver injury in mice inducible by concanavalin A

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

The physiological consequences of glutathione variations.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

On the antioxidant effects of ascorbic acid and glutathione

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Apoptosis signaling by death receptors.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Disparate roles for TNF-alpha and Fas ligand in concanavalin A-induced hepatitis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Activation of caspase 3 (CPP32)-like proteases is essential for TNF-alpha-induced hepatic parenchymal cell apoptosis and neutrophil-mediated necrosis in a murine endotoxin shock model.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Sequential activation of ICE-like and CPP32-like proteases during Fas-mediated apoptosis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Glutathione depletion in rats impairs T-cell and macrophage immune function.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Functions of glutathione and glutathione disulfide in immunology and immunopathology.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Interleukin-1 beta converting enzyme.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Differential effects of glutathione depletion on T cell subsets

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850090

Apoptosis in liver disease

25 September 2018

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Low content of hepatic reduced glutathione in patients with Wilson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Diurnal fluctuation and pharmacological alteration of mouse organ glutathione content

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Glutathione: a protective mechanism against hepatotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Redox manipulation using the thiol-oxidizing agent diethyl maleate prevents hepatocellular necrosis and apoptosis in a rodent endotoxemia model

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Rapid and specific efflux of reduced glutathione during apoptosis induced by anti-Fas/APO-1 antibody

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

LPS challenge in D-galactosamine-sensitized mice accounts for caspase-dependent fulminant hepatitis, not for septic shock

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Tumor necrosis factor-induced apoptosis during the poisoning of mice with hepatotoxins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Concanavalin A hepatotoxicity in mice: tumor necrosis factor-mediated organ failure independent of caspase-3-like protease activation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

N-Acetylcysteine and glutathione as inhibitors of tumor necrosis factor production

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Concanavalin A-induced liver cell damage: activation of intracellular pathways triggered by tumor necrosis factor in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Inhibition of concanavalin A-induced hepatic injury of mice by bacterial lipopolysaccharide via the induction of IL-6 and the subsequent reduction of IL-4: the cytokine milieu of concanavalin A hepatitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

In vivo evidence for a functional role of both tumor necrosis factor (TNF) receptors and transmembrane TNF in experimental hepatitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Thiol regulation of the production of TNF-alpha, IL-6 and IL-8 by human alveolar macrophages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Involvement of Fas/Fas ligand system-mediated apoptosis in the development of concanavalin A-induced hepatitis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Immunopathogenesis of hepatic fibrosis in chronic liver injury induced by repeatedly administered concanavalin A

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Hepatic failure and liver cell damage in acute Wilson's disease involve CD95 (APO-1/Fas) mediated apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Inhibition of Fas receptor (CD95)-induced hepatic caspase activation and apoptosis by acetaminophen in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Histology of the liver in Wilson's disease: a study of 34 cases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965076-6

Mechanisms of hepatic toxicity. I. TNF-induced liver injury

7 January 2021

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12 December 2020

Requirement of IL-4 and liver NK1+ T cells for concanavalin A-induced hepatic injury in mice

1 reference

12 December 2020

Mitochondrial lipid peroxides and antioxidant enzymes in the liver following phorone-induced glutathione depletion

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12 December 2020

Cytokine-mediated hepatic apoptosis

1 reference

12 December 2020

10.1016/S0002-9440(10)65076-6

Identifiers

DOI

1 reference

10 August 2017

1 reference

10 August 2017

1 reference