(Q35747037)

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Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice

scientific article published on August 2001

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11485902%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Immunization with a nontoxic/nonfibrillar amyloid-beta homologous peptide reduces Alzheimer's disease-associated pathology in transgenic mice (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11485902%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Alzheimer's disease

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Einar M Sigurdsson

1

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10 November 2019

Thomas Wisniewski

5

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10 November 2019

author name string

H Scholtzova

2

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10 November 2019

P D Mehta

3

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10 November 2019

B Frangione

4

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10 November 2019

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1 August 2001

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10 November 2019

The American Journal of Pathology

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10 November 2019

159

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10 November 2019

2

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10 November 2019

439-447

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10 November 2019

The pathogenesis of Alzheimer's disease. Is amyloid beta-protein the beginning or the end?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850561

12 July 2018

Toward a comprehensive theory for Alzheimer's disease. Hypothesis: Alzheimer's disease is caused by the cerebral accumulation and cytotoxicity of amyloid beta-protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850561

12 July 2018

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

1 reference

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12 July 2018

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

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12 July 2018

Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier

1 reference

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12 July 2018

Nasal administration of amyloid-beta peptide decreases cerebral amyloid burden in a mouse model of Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850561

12 July 2018

Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

1 reference

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12 July 2018

Biochemical detection of Abeta isoforms: implications for pathogenesis, diagnosis, and treatment of Alzheimer's disease

1 reference

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12 July 2018

Approaches to discovery and characterization of inhibitors of amyloid beta-peptide polymerization

1 reference

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12 July 2018

Inflammation and Alzheimer's disease

1 reference

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12 July 2018

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

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12 July 2018

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

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12 July 2018

Stereological methods for estimating the total number of neurons and synapses: issues of precision and bias

1 reference

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12 July 2018

Recognition sequence design for peptidyl modulators of beta-amyloid aggregation and toxicity.

1 reference

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12 July 2018

Beta-sheet breaker peptides inhibit fibrillogenesis in a rat brain model of amyloidosis: implications for Alzheimer's therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850561

12 July 2018

Bilateral injections of amyloid-beta 25-35 into the amygdala of young Fischer rats: behavioral, neurochemical, and time dependent histopathological effects

1 reference

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12 July 2018

Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

1 reference

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12 July 2018

Local and distant histopathological effects of unilateral amyloid-beta 25-35 injections into the amygdala of young F344 rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1850561

12 July 2018

Can blood-brain barrier play a role in the development of cerebral amyloidosis and Alzheimer's disease pathology.

1 reference

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12 July 2018

Disaggregation of Alzheimer beta-amyloid by site-directed mAb.

1 reference

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12 July 2018

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

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12 July 2018

Fibrillogenesis of synthetic amyloid-beta peptides is dependent on their initial secondary structure

1 reference

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12 July 2018

Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptide

1 reference

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12 July 2018

The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease

1 reference

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12 July 2018

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

1 reference

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12 July 2018

Blood-brain barrier transport of circulating Alzheimer's amyloid beta

1 reference

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12 July 2018

Cerebrospinal fluid inhibits Alzheimer beta-amyloid fibril formation in vitro.

1 reference

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12 July 2018

Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain.

1 reference

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12 July 2018

Fact and speculation on the function of immune response genes in antigen presentation

1 reference

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12 July 2018

Neurotoxicity of a fragment of the amyloid precursor associated with Alzheimer's disease

1 reference

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The antigenic index: a novel algorithm for predicting antigenic determinants.

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In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity

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12 July 2018

Conservation of the sequence of the Alzheimer's disease amyloid peptide in dog, polar bear and five other mammals by cross-species polymerase chain reaction analysis

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Analysis of the circular dichroism spectrum of proteins using the convex constraint algorithm: a practical guide.

1 reference

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12 July 2018

Amyloid beta40/42 clearance across the blood-brain barrier following intra-ventricular injections in wild-type, apoE knock-out and human apoE3 or E4 expressing transgenic mice.

1 reference

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25 September 2018

Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain

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25 September 2018

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

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25 September 2018

In vivo reversal of amyloid-beta lesions in rat brain.

1 reference

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25 September 2018

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1 reference

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1 reference

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12 December 2020

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10.1016/S0002-9440(10)61715-4

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10 November 2019

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Europe PubMed Central

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10 November 2019

PubMed publication ID

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Europe PubMed Central

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10 November 2019

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