(Q35747402)

10 August 2017

title

A second generation of double mutant cholera toxin adjuvants: enhanced immunity without intracellular trafficking (English)

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10 August 2017

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Yukari Hagiwara

1

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10 August 2017

Yuki I Kawamura

2

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10 August 2017

Kosuke Kataoka

3

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10 August 2017

Bibi Rahima

4

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10 August 2017

Raymond J Jackson

5

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10 August 2017

Katsuhiro Komase

6

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10 August 2017

Taeko Dohi

7

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10 August 2017

Prosper N Boyaka

8

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10 August 2017

Yoshifumi Takeda

9

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10 August 2017

Hiroshi Kiyono

10

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10 August 2017

Jerry R McGhee

11

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10 August 2017

Kohtaro Fujihashi

12

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10 August 2017

language of work or name

English

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publication date

1 September 2006

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10 August 2017

published in

Journal of Immunology

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10 August 2017

volume

177

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10 August 2017

issue

5

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10 August 2017

page(s)

3045-3054

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describes a project that uses

10 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4469177/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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The cholera toxin-derived CTA1-DD vaccine adjuvant administered intranasally does not cause inflammation or accumulate in the nervous tissues

12 July 2018

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Mucosal immunisation and adjuvants: a brief overview of recent advances and challenges

12 July 2018

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A nontoxic chimeric enterotoxin adjuvant induces protective immunity in both mucosal and systemic compartments with reduced IgE antibodies.

12 July 2018

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Cutting edge: the mucosal adjuvant cholera toxin redirects vaccine proteins into olfactory tissues

12 July 2018

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ER-Tracker dye and BODIPY-brefeldin A differentiate the endoplasmic reticulum and golgi bodies from the tubular-vacuole system in living hyphae of Pisolithus tinctorius.

12 July 2018

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Transport of bacterial lipopolysaccharide to the golgi apparatus

12 July 2018

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KDEL receptor (Erd2p)-mediated retrograde transport of the cholera toxin A subunit from the Golgi involves COPI, p23, and the COOH terminus of Erd2p

12 July 2018

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Mucosal adjuvanticity and immunogenicity of LTR72, a novel mutant of Escherichia coli heat-labile enterotoxin with partial knockout of ADP-ribosyltransferase activity

12 July 2018

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Adjuvant activity of the heat-labile enterotoxin from enterotoxigenic Escherichia coli for oral administration of inactivated influenza virus vaccine

12 July 2018

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A nontoxic mutant of cholera toxin elicits Th2-type responses for enhanced mucosal immunity

12 July 2018

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Mutants in the ADP-ribosyltransferase cleft of cholera toxin lack diarrheagenicity but retain adjuvanticity

12 July 2018

1 reference

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Mutants of the Escherichia coli heat-labile enterotoxin with reduced ADP-ribosylation activity or no activity retain the immunogenic properties of the native holotoxin.

12 July 2018

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Induction of antibody-secreting cells and T-helper and memory cells in murine nasal lymphoid tissue

12 July 2018

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gamma/delta T cell-deficient mice have impaired mucosal immunoglobulin A responses

12 July 2018

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Impact of aging on gastrointestinal mucosal immunity

12 July 2018

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Induction of antigen-specific antibodies in vaginal secretions by using a nontoxic mutant of heat-labile enterotoxin as a mucosal adjuvant

12 July 2018

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Acceleration of influenza virus clearance by Th1 cells in the nasal site of mice immunized intranasally with adjuvant-combined recombinant nucleoprotein.

12 July 2018

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Helper T cell subsets for immunoglobulin A responses: oral immunization with tetanus toxoid and cholera toxin as adjuvant selectively induces Th2 cells in mucosa associated tissues

12 July 2018

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A genetically detoxified derivative of heat-labile Escherichia coli enterotoxin induces neutralizing antibodies against the A subunit

12 July 2018

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Mutants of Escherichia coli heat-labile toxin lacking ADP-ribosyltransferase activity act as nontoxic, mucosal adjuvants

12 July 2018

1 reference

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Construction of nontoxic derivatives of cholera toxin and characterization of the immunological response against the A subunit.

12 July 2018

1 reference

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Dissociation of Escherichia coli heat-labile enterotoxin adjuvanticity from ADP-ribosyltransferase activity

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Targeting of cholera toxin and Escherichia coli heat labile toxin in polarized epithelia: role of COOH-terminal KDEL

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Role of a potential endoplasmic reticulum retention sequence (RDEL) and the Golgi complex in the cytotonic activity of Escherichia coli heat-labile enterotoxin.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Enterotoxigenic Escherichia coli Isolated from Patients with Severe Cholera-like Disease

12 July 2018

1 reference

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Detection of Heat-Labile Escherichia coli Enterotoxin with the Use of Adrenal Cells in Tissue Culture

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

An investigation of traveller's diarrhoea.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Adjuvant activity of Escherichia coli heat-labile enterotoxin and effect on the induction of oral tolerance in mice to unrelated protein antigens.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Strong adjuvant properties of cholera toxin on gut mucosal immune responses to orally presented antigens

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Immunological Principles and Emerging Strategies of Vaccination for the Elderly

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Purification and partial characterization of heat-stable enterotoxin of enterotoxigenic Escherichia coli

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Fluid accumulation in mouse ligated intestine inoculated with Clostridium perfringens enterotoxin

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Mucosal antibody response induced with a nasal virosome-based influenza vaccine.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Protective mucosal immunity in aging is associated with functional CD4+ T cells in nasopharyngeal-associated lymphoreticular tissue

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Effects of intranasal administration of cholera toxin (or Escherichia coli heat-labile enterotoxin) B subunits supplemented with a trace amount of the holotoxin on the brain.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Transport of an external Lys-Asp-Glu-Leu (KDEL) protein from the plasma membrane to the endoplasmic reticulum: studies with cholera toxin in Vero cells

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Simple method of purification of Escherichia coli heat-labile enterotoxin and cholera toxin using immobilized galactose.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4469177

Toxigenic Escherichia coli in infantile diarrhea in Chicago

25 September 2018

1 reference

12 December 2020

Mucosal adjuvant effect of cholera toxin in mice results from induction of T helper 2 (Th2) cells and IL-4

1 reference

12 December 2020

Cholera toxin feeding did not induce oral tolerance in mice and abrogated oral tolerance to an unrelated protein antigen

1 reference

12 December 2020

Mutants of cholera toxin as an effective and safe adjuvant for nasal influenza vaccine

1 reference

12 December 2020

A novel adjuvant for mucosal immunity to HIV-1 gp120 in nonhuman primates

1 reference

12 December 2020

Nasopharyngeal-associated lymphoreticular tissue (NALT) immunity: fimbriae-specific Th1 and Th2 cell-regulated IgA responses for the inhibition of bacterial attachment to epithelial cells and subsequent inflammatory cytokine production

1 reference

12 December 2020

A nontoxic adjuvant for mucosal immunity to pneumococcal surface protein A

1 reference

12 December 2020

Characterization of mouse nasal lymphocytes isolated by enzymatic extraction with collagenase

1 reference

12 December 2020

Chemiluminescence Immunoassay for Progesterone in Plasma Incorporating Acridinium Ester Labelled Antigen

1 reference

12 December 2020

Safety and immunogenicity of intranasally administered inactivated trivalent virosome-formulated influenza vaccine containing Escherichia coli heat-labile toxin as a mucosal adjuvant

1 reference

12 December 2020

The adjuvant effect of Vibrio cholerae and Escherichia coli heat-labile enterotoxins is linked to their ADP-ribosyltransferase activity

1 reference

12 December 2020

Evidence for early aging in the mucosal immune system

1 reference

12 December 2020

Nasal immune system: distinctive Th0 and Th1/Th2 type environments in murine nasal-associated lymphoid tissues and nasal passage, respectively

1 reference

12 December 2020

10.4049/JIMMUNOL.177.5.3045

Identifiers

DOI

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10 August 2017

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10 August 2017

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