(Q35749881)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232659%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Mechanism of proton/substrate coupling in the heptahelical lysosomal transporter cystinosin (English)

1 reference

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20 January 2020

1

1 reference

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20 January 2020

Michael Pusch

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232659%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Stéphane Supplisson

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232659%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

author name string

Gian Carlo Bellenchi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232659%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Xiong Chen

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232659%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Giovanni Zifarelli

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232659%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Corinne Sagné

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232659%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Cécile Debacker

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232659%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Bruno Gasnier

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232659%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

language of work or name

English

0 references

publication date

9 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232659%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

20 January 2020

published in

1 reference

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20 January 2020

volume

109

1 reference

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20 January 2020

issue

5

1 reference

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20 January 2020

page(s)

E210-7

1 reference

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describes a project that uses

20 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3277178/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Structure of a eukaryotic CLC transporter defines an intermediate state in the transport cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Ion channels versus ion pumps: the principal difference, in principle

27 July 2018

1 reference

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Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

The ClC-0 chloride channel is a 'broken' Cl-/H+ antiporter

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Protons and how they are transported by proton pumps.

27 July 2018

1 reference

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Molecular physiology and pathophysiology of lysosomal membrane transporters

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

The structural basis of calcium transport by the calcium pump

27 July 2018

1 reference

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Proton transfers in the bacteriorhodopsin photocycle

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Chloride/proton antiporter activity of mammalian CLC proteins ClC-4 and ClC-5.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

ERS1 encodes a functional homologue of the human lysosomal cystine transporter

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Leptosphaeria rhodopsin: bacteriorhodopsin-like proton pump from a eukaryote

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Unique structure and function of chloride transporting CLC proteins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Properties of single voltage-gated proton channels in human eosinophils estimated by noise analysis and by direct measurement

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

New aspects of the pathogenesis of cystinosis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Dynamic equilibrium between coupled and uncoupled modes of a neuronal glutamate transporter

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Coupled and uncoupled proton movement by amino acid transport system N.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

MPDU1 mutations underlie a novel human congenital disorder of glycosylation, designated type If

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

A mutation in the human MPDU1 gene causes congenital disorder of glycosylation type If (CDG-If)

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Homologues of archaeal rhodopsins in plants, animals and fungi: structural and functional predications for a putative fungal chaperone protein

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

The targeting of cystinosin to the lysosomal membrane requires a tyrosine-based signal and a novel sorting motif

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Retinylidene proteins: structures and functions from archaea to humans.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

GAT1 (GABA:Na+:Cl-) cotransport function. Kinetic studies in giant Xenopus oocyte membrane patches

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

CTNS mutations in an American-based population of cystinosis patients

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

The voltage dependence of a cloned mammalian renal type II Na+/Pi cotransporter (NaPi-2).

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

SMART, a simple modular architecture research tool: identification of signaling domains

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Proton conduction in gramicidin A and in its dioxolane-linked dimer in different lipid bilayers

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Deuterium isotope effects on permeation and gating of proton channels in rat alveolar epithelium

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Expression cloning of a novel suppressor of the Lec15 and Lec35 glycosylation mutations of Chinese hamster ovary cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

An excitatory amino-acid transporter with properties of a ligand-gated chloride channel

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Cystine transport is defective in isolated leukocyte lysosomes from patients with cystinosis

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Ionic Blockage of Sodium Channels in Nerve

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Electrogenic properties of the sodium-alanine cotransporter in pancreatic acinar cells: II. Comparison with transport models.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Voltage dependence of Na translocation by the Na/K pump.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Characterization of the lysosomal cystine transport system in mouse L-929 fibroblasts

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

ClC chloride channels viewed through a transporter lens

27 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

Review. Peering into an ATPase ion pump with single-channel recordings.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

The ion pathway through the opened Na(+),K(+)-ATPase pump

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

Determinants of anion-proton coupling in mammalian endosomal CLC proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

Xanthorhodopsin: a proton pump with a light-harvesting carotenoid antenna.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

Novel protein domains and repeats in Drosophila melanogaster: insights into structure, function, and evolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

Severity of phenotype in cystinosis varies with mutations in the CTNS gene: predicted effect on the model of cystinosin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

GAT1 (GABA:Na+:Cl-) cotransport function. Database reconstruction with an alternating access model

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

Unlocking the molecular secrets of sodium-coupled transporters.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

Neurological disease mutations compromise a C-terminal ion pathway in the Na(+)/K(+)-ATPase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

Torque generation and elastic power transmission in the rotary F(O)F(1)-ATPase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

The role of protons in fast and slow gating of the Torpedo chloride channel ClC-0.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

The proton-driven rotor of ATP synthase: ohmic conductance (10 fS), and absence of voltage gating

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

Determination of proton flux and conductance at pH 6.8 through single FO sectors from Escherichia coli

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

Kinetics of a human glutamate transporter.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Steady states, charge movements, and rates for a cloned GABA transporter expressed in Xenopus oocytes.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

ATP-dependent lysosomal cystine efflux is defective in cystinosis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Electrogenic properties of the cloned Na+/glucose cotransporter: I. Voltage-clamp studies

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277178

Ion permeation through the Na+,K+-ATPase

25 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1115581109

21 January 2018

Identifiers

DOI

10.1073/PNAS.1115581109

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232659%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232659%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22232659%20AND%20SRC:MED&resulttype=core&format=json