(Q35751162)

English

Wilms' tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repression

scientific article published on 4 September 2010

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scholarly article

1 reference

Europe PubMed Central

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13 February 2020

Wilms' tumor 1 silencing decreases the viability and chemoresistance of glioblastoma cells in vitro: a potential role for IGF-1R de-repression (English)

1 reference

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13 February 2020

1 reference

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inferred from title

Helen L. Fillmore

7

1 reference

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13 February 2020

author name string

Mike Y Chen

1

1 reference

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13 February 2020

Aaron J Clark

2

1 reference

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13 February 2020

Dana C Chan

3

1 reference

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13 February 2020

Joy L Ware

4

1 reference

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13 February 2020

Shawn E Holt

5

1 reference

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13 February 2020

Archana Chidambaram

6

1 reference

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13 February 2020

William C Broaddus

8

1 reference

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13 February 2020

publication date

4 September 2010

1 reference

Europe PubMed Central

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13 February 2020

Journal of Neuro-Oncology

1 reference

Europe PubMed Central

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13 February 2020

103

1 reference

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13 February 2020

87-102

1 reference

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13 February 2020

1

1 reference

Europe PubMed Central

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13 February 2020

https://scigraph.springernature.com/pub.10.1007/s11060-010-0374-7

0 references

Wilms tumor 1 expression in malignant gliomas and correlation of +KTS isoforms with p53 status

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

The relationship between six-month progression-free survival and 12-month overall survival end points for phase II trials in patients with glioblastoma multiforme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Autophagy delays apoptotic death in breast cancer cells following DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

hnRNP-U directly interacts with WT1 and modulates WT1 transcriptional activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

WT1 influences apoptosis through transcriptional regulation of Bcl-2 family members

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Autophagic cell death of malignant glioma cells induced by a conditionally replicating adenovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Antiapoptotic function of 17AA(+)WT1 (Wilms' tumor gene) isoforms on the intrinsic apoptosis pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

The antiapoptotic gene A1/BFL1 is a WT1 target gene that mediates granulocytic differentiation and resistance to chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

WT1 induces apoptosis through transcriptional regulation of the proapoptotic Bcl-2 family member Bak.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

HER2/neu increases the expression of Wilms' Tumor 1 (WT1) protein to stimulate S-phase proliferation and inhibit apoptosis in breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

INO80 and gamma-H2AX interaction links ATP-dependent chromatin remodeling to DNA damage repair.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Overexpression of the Wilms' tumor gene W T1 in primary astrocytic tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Ataxia-telangiectasia mutated gene controls insulin-like growth factor I receptor gene expression in a deoxyribonucleic acid damage response pathway via mechanisms involving zinc-finger transcription factors Sp1 and WT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Transcriptional activation of c-myc proto-oncogene by WT1 protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Pivotal role of the cell death factor BNIP3 in ceramide-induced autophagic cell death in malignant glioma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Paraptosis: mediation by MAP kinases and inhibition by AIP-1/Alix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Role of autophagy in temozolomide-induced cytotoxicity for malignant glioma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

WT1-p53 interactions in insulin-like growth factor-I receptor gene regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Downregulation of Wilms' tumor 1 protein inhibits breast cancer proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Cyclin E is a target of WT1 transcriptional repression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Descriptive epidemiology of primary brain and CNS tumors: results from the Central Brain Tumor Registry of the United States, 1990-1994

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Wilms' tumor suppressor gene (WT1) is expressed in primary breast tumors despite tumor-specific promoter methylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Transcriptional regulation of insulin-like growth factor-I receptor gene expression in prostate cancer cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

An alternative, nonapoptotic form of programmed cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

The Wilms' tumor gene product WT1 mediates the down-regulation of the rat epidermal growth factor receptor by nerve growth factor in PC12 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Internal translation initiation generates novel WT1 protein isoforms with distinct biological properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Expression of the Wilms' tumor gene WT1 in solid tumors and its involvement in tumor cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Brain tumor survival: results from the National Cancer Data Base

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Type-1 insulin-like growth factor receptor reexpression in the malignant phenotype of SV40-T-immortalized human prostate epithelial cells enhances apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

The WT1 protein is a negative regulator of the normal bcl-2 allele in t(14;18) lymphomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Reexpression of the type 1 insulin-like growth factor receptor inhibits the malignant phenotype of simian virus 40 T antigen immortalized human prostate epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

A novel repressor, par-4, modulates transcription and growth suppression functions of the Wilms' tumor suppressor WT1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Regulation of insulin-like growth factor I receptor gene expression by the Wilms' tumor suppressor WT1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

RNA binding by the Wilms tumor suppressor zinc finger proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

A WT1 antisense oligonucleotide inhibits proliferation and induces apoptosis in myeloid leukaemia cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

WT-1 is required for early kidney development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Influence of location and extent of surgical resection on survival of patients with glioblastoma multiforme: results of three consecutive Radiation Therapy Oncology Group (RTOG) clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Expression of the wt1 Wilms' tumor gene by normal and malignant human melanocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

RNA editing in the Wilms' tumor susceptibility gene, WT1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

WT1 suppresses synthesis of the epidermal growth factor receptor and induces apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Regulation of the proto-oncogenes bcl-2 and c-myc by the Wilms' tumor suppressor gene WT1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

WT1 induces expression of insulin-like growth factor 2 in Wilms' tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

The role of a low pH intracellular compartment in the processing, storage, and secretion of ACTH and endorphin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

The candidate Wilms' tumour gene is involved in genitourinary development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Alternative splicing and genomic structure of the Wilms tumor gene WT1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Expression of the Wilms' tumor gene (WT1) in human leukemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Evaluation of BCNU and/or radiotherapy in the treatment of anaplastic gliomas. A cooperative clinical trial

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

12 July 2018

Expression of the Wilms' tumor gene product WT1 in glioblastomas and medulloblastomas.

1 reference

https://api.crossref.org/works/10.1007%2FS11060-010-0374-7

21 January 2018

The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo.

1 reference

https://api.crossref.org/works/10.1007%2FS11060-010-0374-7

21 January 2018

Wilms' tumour gene 1 (WT1) in human neoplasia.

1 reference

https://api.crossref.org/works/10.1007%2FS11060-010-0374-7

21 January 2018

Physical interaction between Wilms tumor 1 and p73 proteins modulates their functions.

1 reference

https://api.crossref.org/works/10.1007%2FS11060-010-0374-7

21 January 2018

Overexpression of the Wilms' tumor gene WT1 in pancreatic ductal adenocarcinoma.

1 reference

https://api.crossref.org/works/10.1007%2FS11060-010-0374-7

21 January 2018

WT1 modulates apoptosis by transcriptionally upregulating the bcl-2 proto-oncogene

1 reference

https://api.crossref.org/works/10.1007%2FS11060-010-0374-7

21 January 2018

Living T9 glioma cells expressing membrane macrophage colony-stimulating factor produce immediate tumor destruction by polymorphonuclear leukocytes and macrophages via a "paraptosis"-induced pathway that promotes systemic immunity against intracrani

1 reference

https://api.crossref.org/works/10.1007%2FS11060-010-0374-7

21 January 2018

Human U251MG glioma cells expressing the membrane form of macrophage colony-stimulating factor (mM-CSF) are killed by human monocytes in vitro and are rejected within immunodeficient mice via paraptosis that is associated with increased expression o

1 reference

https://api.crossref.org/works/10.1007%2FS11060-010-0374-7

21 January 2018

Oncogenic Ras triggers cell suicide through the activation of a caspase-independent cell death program in human cancer cells.

1 reference

https://api.crossref.org/works/10.1007%2FS11060-010-0374-7

21 January 2018

Enhanced radiosensitivity of malignant glioma cells after adenoviral p53 transduction

1 reference

https://api.crossref.org/works/10.1007%2FS11060-010-0374-7

21 January 2018

Frequent co-alterations of TP53, p16/CDKN2A, p14ARF, PTEN tumor suppressor genes in human glioma cell lines.

1 reference

https://api.crossref.org/works/10.1007%2FS11060-010-0374-7

21 January 2018

A functional interaction with CBP contributes to transcriptional activation by the Wilms tumor suppressor WT1.

1 reference

https://api.crossref.org/works/10.1007%2FS11060-010-0374-7

21 January 2018

Radiation-induced autophagy is associated with LC3 and its inhibition sensitizes malignant glioma cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

25 September 2018

Induction of autophagic cell death in malignant glioma cells by arsenic trioxide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

25 September 2018

Inhibition of tumorigenesis and induction of apoptosis in human tumor cells by the stable expression of a myristylated COOH terminus of the insulin-like growth factor I receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

25 September 2018

Expression of the insulin-like growth factor I receptor C terminus as a myristylated protein leads to induction of apoptosis in tumor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3277601

25 September 2018

Phase II clinical trial of Wilms tumor 1 peptide vaccination for patients with recurrent glioblastoma multiforme

1 reference

https://pubmed.ncbi.nlm.nih.gov/20820871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of insulin-like growth factor I receptor promoter activity by wild-type and mutant versions of the WT1 tumor suppressor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20820871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transcriptional regulation by the Wilms' tumour suppressor protein WT1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20820871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20820871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergism of taxol and gallium nitrate in human breast carcinoma cells: schedule dependency

1 reference

https://pubmed.ncbi.nlm.nih.gov/20820871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Induction of p21 by the Wilms' tumor suppressor gene WT1

1 reference

https://pubmed.ncbi.nlm.nih.gov/20820871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosine kinase inhibitor emodin suppresses growth of HER-2/neu-overexpressing breast cancer cells in athymic mice and sensitizes these cells to the inhibitory effect of paclitaxel

1 reference

https://pubmed.ncbi.nlm.nih.gov/20820871

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11060-010-0374-7

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20820871%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20820871%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20820871%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

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