(Q35753502)

English

Specific K-ras2 mutations in human sporadic colorectal adenomas are associated with DNA near-diploid aneuploidy and inhibition of proliferation

scientific article published on October 1998

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Specific K-ras2 mutations in human sporadic colorectal adenomas are associated with DNA near-diploid aneuploidy and inhibition of proliferation (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

author name string

W Giaretti

1

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

A Rapallo

2

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

E Geido

3

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

A Sciutto

4

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

F Merlo

5

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

M Risio

6

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

F P Rossini

7

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

language of work or name

0 references

publication date

1 October 1998

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

The American Journal of Pathology

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

153

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

4

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

1201-1209

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Ras links growth factor signaling to the cell cycle machinery via regulation of cyclin D1 and the Cdk inhibitor p27KIP1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Lessons from hereditary colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Going mobile: microtubule motors and chromosome segregation

1 reference

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2 October 2017

Intratumor heterogeneity of K-ras2 mutations in colorectal adenocarcinomas: association with degree of DNA aneuploidy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Abnormal centrosome amplification in the absence of p53.

1 reference

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2 October 2017

Consensus review of the clinical utility of DNA flow cytometry in colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Cell cycle control and cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Comparative genomic hybridization: an overview

1 reference

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2 October 2017

Small GTP-binding proteins and the regulation of the actin cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives.

1 reference

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2 October 2017

p21ras: An oncoprotein functioning in growth factor-induced signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Direction of p21ras-generated signals towards cell growth or apoptosis is determined by protein kinase C and Bcl-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Mutations activating human c-Ha-ras1 protooncogene (HRAS1) induced by chemical carcinogens and depurination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

DNA repair, oncogenes and carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Progressive dysplasia and aneuploidy are hallmarks of mouse skin papillomas: relevance to malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Carcinogen-specific mutation and amplification of Ha-ras during mouse skin carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Genetic alterations during colorectal-tumor development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Endogenous carcinogenesis: molecular oncology into the twenty-first century--presidential address.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Mutations in the KRAS2 oncogene during progressive stages of human colon carcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

ras oncogenes in human cancer: a review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

ras GTPase activating protein: signal transmitter and signal terminator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

A genetic model for colorectal tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Carcinogen-induced mutations in the mouse c-Ha-ras gene provide evidence of multiple pathways for tumor progression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Frequency and spectrum of mutations at codons 12 and 13 of the c-K-ras gene in human tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Regulators and Effectors of ras Proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

2 October 2017

Increasing complexity of Ras signal transduction: involvement of Rho family proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

12 July 2018

Transfection of human mutated K-ras in mouse NIH-3T3 cells is associated with increased cloning efficiency and DNA aneuploidization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

12 July 2018

Increased expression of cyclin D1 is an early event in multistage colorectal carcinogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

12 July 2018

Further evidence that one of the earliest alterations in colorectal carcinogenesis involves APC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

12 July 2018

Induction of apoptosis in NIH3T3 cells after serum deprivation by overexpression of rho-p21, a GTPase protein of the ras superfamily.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

12 July 2018

Diploid predominance in hereditary nonpolyposis colorectal carcinoma evaluated by flow cytometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

12 July 2018

High expression of ras p21 correlates with increased rate of abnormal mitosis in NIH3T3 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

12 July 2018

Atypical mitoses in colorectal adenomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

12 July 2018

Neoplastic progression in ulcerative colitis: histology, DNA content, and loss of a p53 allele.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

12 July 2018

Aneuploidy mechanisms in human colorectal preneoplastic lesions and Barrett's esophagus. Is there a role for K-ras and p53 mutations?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

25 September 2018

Comparative genomic hybridization reveals a specific pattern of chromosomal gains and losses during the genesis of colorectal tumors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

25 September 2018

Deletions at chromosome 1p by fluorescence in situ hybridization are an early event in human colorectal tumorigenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

25 September 2018

Inhibition of ras-induced proliferation and cellular transformation by p16INK4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1853049

25 September 2018

Prevalence of ras gene mutations in human colorectal cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965664-7

7 January 2021

Activation of the K-ras oncogene in colorectal neoplasms is associated with decreased apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965664-7

7 January 2021

K-ras-2 G-C and G-T transversions correlate with DNA aneuploidy in colorectal adenomas

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965664-7

7 January 2021

DNA flow cytometry of endoscopically examined colorectal adenomas and adenocarcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965664-7

7 January 2021

Tumor progression by DNA flow cytometry in human colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965664-7

7 January 2021

Frequent and characteristic K-ras activation and absence of p53 protein accumulation in aberrant crypt foci of the colon

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965664-7

7 January 2021

Aberrant crypt foci and K-ras mutations: earliest recognized players or innocent bystanders in colon carcinogenesis?

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965664-7

7 January 2021

Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965664-7

7 January 2021

A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965664-7

7 January 2021

Genetic instability in colorectal cancers

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965664-7

7 January 2021

Correlation between 1p deletions and aneusomy in human colorectal adenomas

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965664-7

7 January 2021

Clonal karyotypic abnormalities in colorectal adenomas: Clues to the early genetic events in the adenoma‐carcinoma sequence

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965664-7

7 January 2021

Fractal modeling of pulmonary blood flow heterogeneity

1 reference

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7 January 2021

Barrett's esophagus: cell cycle abnormalities in advancing stages of neoplastic progression

1 reference

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7 January 2021

A p53-dependent mouse spindle checkpoint

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2965664-7

7 January 2021

Prevalence of G-to-T transversions among K-ras oncogene mutations in human colorectal tumors in Yugoslavia

1 reference

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7 January 2021

Nonsteroidal anti-inflammatory drug use and sporadic colorectal adenomas

1 reference

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7 January 2021

p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9777951

12 December 2020

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inferred from PubMed ID database lookup

Deletion of 1p36 as a primary chromosomal aberration in intestinal tumorigenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/9777951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A model of DNA aneuploidization and evolution in colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9777951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scanning microphotometry image analysis of Ha-ras-transformed human breast epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/9777951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of apoptosis during development of colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9777951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

K-ras gene mutations in early colorectal cancer ... flat elevated vs polyp-forming cancer....

1 reference

https://pubmed.ncbi.nlm.nih.gov/9777951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flow cytometric detection of aneuploidy in colorectal adenomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/9777951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Progression to cancer in Barrett's esophagus is associated with genomic instability

1 reference

https://pubmed.ncbi.nlm.nih.gov/9777951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Model for the genetic evolution of human solid tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/9777951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Emergence of adenomatous aberrant crypt foci (ACF) from hyperplastic ACF with concomitant increase in cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/9777951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/S0002-9440(10)65664-7

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

release_7sysyznu2zhnlbcnnl5z24p7sm

1 reference

https://api.fatcat.wiki/v0/release/7sysyznu2zhnlbcnnl5z24p7sm

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

ResearchGate publication ID

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