(Q35756498)

10 August 2017

title

Depression of maximum rate of depolarization of guinea-pig ventricular action potentials by metabolites of encainide (English)

1 reference

10 August 2017

Hemsworth PD

1

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10 August 2017

Campbell TJ

series ordinal

2

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10 August 2017

language of work or name

English

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publication date

1 June 1989

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British Journal of Pharmacology

10 August 2017

published in

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10 August 2017

volume

97

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10 August 2017

issue

2

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10 August 2017

page(s)

619-625

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Kinetics of onset of rate-dependent effects of Class I antiarrhythmic drugs are important in determining their effects on refractoriness in guinea-pig ventricle, and provide a theoretical basis for their subclassification

10 August 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

Importance of physico-chemical properties in determining the kinetics of the effects of Class I antiarrhythmic drugs on maximum rate of depolarization in guinea-pig ventricle

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

Encainide and its metabolites. Comparative effects in man on ventricular arrhythmia and electrocardiographic intervals

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

Cellular electrophysiological effects of D- and DL-sotalol in guinea-pig sinoatrial node, atrium and ventricle and human atrium: differential tissue sensitivity.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

Quantitative structure/activity relations based on use-dependent block and repriming kinetics in myocardium

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

Antiarrhythmic properties of MJ 9067 in acute animal models

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

The relation of Vmax to INa, GNa, and h infinity in a model of the cardiac Purkinje fiber

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

A Specific Effect of Lidocaine and Tocainide on Ventricular Conduction of Mid-Range Extrasystoles

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

Time-independent effects on cardiac action potential upstroke velocity (resting block) and lipid solubility of beta adrenergic blockers

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

Action potential prolongation and induction of abnormal automaticity by low quinidine concentrations in canine Purkinje fibers. Relationship to potassium and cycle length.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

Selective depression of conduction of premature action potentials in canine Purkinje fibres by class Ib antiarrhythmic drugs: comparison with Ia and Ic drugs.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

Antiarrhythmic drug classification: new science and practical applications

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

Fast frequency-dependent block of action potential upstroke in rabbit atrium by small local anesthetics

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

Resting and rate-dependent depression of maximum rate of depolarisation (Vmax) in guinea pig ventricular action potentials by mexiletine, disopyramide, and encainide.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1854529

Total suppression of ventricular arrhythmias by encainide. Pharmacokinetic and electrocardiographic characteristics

25 September 2018

1 reference

12 December 2020

Encainide: a new and potent antiarrhythmic agent

1 reference

12 December 2020

Malignant ventricular tachyarrhythmias associated with the use of encainide

1 reference

12 December 2020

Effects of encainide and metabolites (MJ14030 and MJ9444) on canine cardiac Purkinje and ventricular fibers

1 reference

12 December 2020

Metabolite cumulation during long-term oral encainide administration

1 reference

12 December 2020

Treatment of frequent ventricular arrhythmia with encainide: assessment using serial ambulatory electrocardiograms, intracardiac electrophysiologic studies, treadmill exercise tests, and radionuclide cineangiographic studies

1 reference

12 December 2020

Effect of encainide and its two major metabolites on cardiac conduction

1 reference

12 December 2020

Comparative study of encainide and disopyramide in chronic ventricular arrhythmias: a double-blind placebo-controlled crossover study

1 reference

12 December 2020

Aggravation of ventricular arrhythmia. A drug-induced complication

1 reference

12 December 2020

Dose-response range of encainide for benign and potentially lethal ventricular arrhythmias

1 reference

12 December 2020

Qualitative and quantitative comparison of the cardiac effects of encainide and its three major metabolites in the dog

1 reference

12 December 2020

Antiarrhythmic activity, electrocardiographic effects and pharmacokinetics of the encainide metabolites O-desmethyl encainide and 3-methoxy-O-desmethyl encainide in man

1 reference

12 December 2020

Electrophysiologic effects of encainide (MJ 9067) on canine Purkinje fibres

1 reference

12 December 2020

10.1111/J.1476-5381.1989.TB11994.X

Identifiers

DOI

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10 August 2017

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10 August 2017

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