(Q35762439)

10 August 2017

title

Novel ChIP-based strategies to uncover transcription factor target genes in the immune system (English)

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10 August 2017

Amy S Weinmann

1

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10 August 2017

publication date

1 May 2004

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Nature Reviews Immunology

10 August 2017

published in

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10 August 2017

volume

4

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10 August 2017

issue

5

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10 August 2017

page(s)

381-386

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Molecular mechanisms regulating Th1 immune responses

10 August 2017

cites work

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Lymphocyte development from hematopoietic stem cells.

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Genome-wide location and function of DNA binding proteins

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Genomic binding sites of the yeast cell-cycle transcription factors SBF and MBF

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E2F integrates cell cycle progression with DNA repair, replication, and G(2)/M checkpoints

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Isolating human transcription factor targets by coupling chromatin immunoprecipitation and CpG island microarray analysis

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Use of chromatin immunoprecipitation to clone novel E2F target promoters

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Distribution of NF-kappaB-binding sites across human chromosome 22

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GATA-1 binding sites mapped in the beta-globin locus by using mammalian chIp-chip analysis

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Chromatin structure and gene regulation in the immune system

31 March 2020

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A novel transcription factor, T-bet, directs Th1 lineage commitment

31 March 2020

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Distinct effects of T-bet in TH1 lineage commitment and IFN-gamma production in CD4 and CD8 T cells

31 March 2020

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T-bet is rapidly induced by interferon-gamma in lymphoid and myeloid cells

31 March 2020

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T-bet is required for optimal production of IFN-gamma and antigen-specific T cell activation by dendritic cells

31 March 2020

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CpG directly induces T-bet expression and inhibits IgG1 and IgE switching in B cells

31 March 2020

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Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin

31 March 2020

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Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction

31 March 2020

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T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

31 March 2020

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GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet

31 March 2020

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T-bet regulates IgG class switching and pathogenic autoantibody production

31 March 2020

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Antigen-driven effector CD8 T cell function regulated by T-bet

31 March 2020

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T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes.

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Genetic analysis of NF- B/Rel transcription factors defines functional specificities

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A Chromatin Immunoprecipitation Screen Reveals Protein Kinase Cβ as a Direct RUNX1 Target Gene

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T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells

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CpG islands as genomic footprints of promoters that are associated with replication origins.

31 March 2020

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Promoter prediction in the human genome.

31 March 2020

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Large-scale human promoter mapping using CpG islands.

31 March 2020

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The identification of E2F1-specific target genes

31 March 2020

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E2F6 negatively regulates BRCA1 in human cancer cells without methylation of histone H3 on lysine 9.

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Control of pancreas and liver gene expression by HNF transcription factors

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Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer.

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Analysis of Myc bound loci identified by CpG island arrays shows that Max is essential for Myc-dependent repression

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A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells

31 March 2020

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Unbiased mapping of transcription factor binding sites along human chromosomes 21 and 22 points to widespread regulation of noncoding RNAs

31 March 2020

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Identification of novel binding elements and gene targets for the homeodomain protein BARX2

31 March 2020

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Identification of target genes for EWS/ATF-1 chimeric transcription factor.

31 March 2020

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In vivo cloning and characterization of a new growth suppressor protein TOE1 as a direct target gene of Egr1.

31 March 2020

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Identification of E2A target genes in B lymphocyte development by using a gene tagging-based chromatin immunoprecipitation system

31 March 2020

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Identification of a binding region for human origin recognition complex proteins 1 and 2 that coincides with an origin of DNA replication

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/NRI1353

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Dimensions Publication ID

10 August 2017

1009739674

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