(Q35767284)

10 August 2017

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title

Beta-cell failure in the pathogenesis of type 2 diabetes mellitus (English)

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10 August 2017

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Jeanne H Steppel

1

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10 August 2017

Edward S Horton

series ordinal

2

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10 August 2017

publication date

1 June 2004

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10 August 2017

published in

Current diabetes report

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10 August 2017

volume

4

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10 August 2017

issue

3

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10 August 2017

page(s)

169-175

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The Significance of Basal Insulin Levels in the Evaluation of the Insulin Response to Glucose in Diabetic and Nondiabetic Subjects*

10 August 2017

cites work

1 reference

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Pancreatic Duodenal Homeobox (PDX-1) in health and disease

21 January 2018

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Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study

21 January 2018

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12 December 2020

Impaired postprandial glucose utilization in non-insulin-dependent diabetes mellitus

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12 December 2020

Long term exposure to fatty acids and ketones inhibits B-cell functions in human pancreatic islets of Langerhans

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12 December 2020

U.K. prospective diabetes study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. U.K. Prospective Diabetes Study Group

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12 December 2020

Lack of control by glucose of ultradian insulin secretory oscillations in impaired glucose tolerance and in non-insulin-dependent diabetes mellitus

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12 December 2020

Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle

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12 December 2020

The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes

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12 December 2020

Lilly lecture 1989. Toward physiological understanding of glucose tolerance. Minimal-model approach

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12 December 2020

Beta-cell dysfunction induced by chronic hyperglycemia. Current ideas on mechanism of impaired glucose-induced insulin secretion

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12 December 2020

Activation of the hexosamine pathway leads to deterioration of pancreatic beta-cell function through the induction of oxidative stress

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12 December 2020

Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial

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12 December 2020

Quantification of the relationship between insulin sensitivity and beta-cell function in human subjects. Evidence for a hyperbolic function.

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12 December 2020

Prevention of type 2 (non-insulin-dependent) diabetes mellitus by diet and physical exercise. The 6-year Malmö feasibility study

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12 December 2020

The natural history of insulin secretory dysfunction and insulin resistance in the pathogenesis of type 2 diabetes mellitus

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12 December 2020

Extensive islet amyloid formation is induced by development of Type II diabetes mellitus and contributes to its progression: pathogenesis of diabetes in a mouse model

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12 December 2020

Loss of early phase of insulin release in humans impairs glucose tolerance and blunts thermic effect of glucose

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12 December 2020

Preservation of pancreatic beta-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk hispanic women

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12 December 2020

History of gestational diabetes leads to distinct metabolic alterations in nondiabetic African-American women with a parental history of type 2 diabetes

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12 December 2020

Reduced beta-cell compensation to the insulin resistance associated with obesity in members of caucasian familial type 2 diabetic kindreds.

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12 December 2020

Lipotoxicity of beta-cells in obesity and in other causes of fatty acid spillover

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12 December 2020

Plasma insulin concentrations in nondiabetic and early diabetic subjects. Determinations by a new sensitive immuno-assay technic

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12 December 2020

Apoptotic signal transduction pathways in diabetes

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12 December 2020

Pancreatic beta-cell loss and preservation in type 2 diabetes

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12 December 2020

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

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12 December 2020

Pancreatic beta-cell dysfunction as the primary genetic lesion in NIDDM. Evidence from studies in normal glucose-tolerant individuals with a first-degree NIDDM relative.

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12 December 2020

Beta-cell function is a major contributor to oral glucose tolerance in high-risk relatives of four ethnic groups in the U.S.

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12 December 2020

Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus

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12 December 2020

Insulin secretion in diabetes mellitus

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12 December 2020

Escape of hepatic glucose production during hyperglycemic clamp

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12 December 2020

Role of reduced suppression of glucose production and diminished early insulin release in impaired glucose tolerance.

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12 December 2020

Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

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12 December 2020

Effects of a 48-h fat infusion on insulin secretion and glucose utilization

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12 December 2020

Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats

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12 December 2020

Effect of loss of first-phase insulin secretion on hepatic glucose production and tissue glucose disposal in humans

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12 December 2020

Endoplasmic reticulum stress-mediated apoptosis in pancreatic beta-cells

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12 December 2020

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

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12 December 2020

Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets

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12 December 2020

Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group.

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12 December 2020

Physiological importance of deficiency in early prandial insulin secretion in non-insulin-dependent diabetes

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12 December 2020

Physiologic evaluation of factors controlling glucose tolerance in man: measurement of insulin sensitivity and beta-cell glucose sensitivity from the response to intravenous glucose

1 reference

12 December 2020

10.1007/S11892-004-0019-3

Identifiers

DOI

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10 August 2017

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