(Q35769584)

English

Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia.

scientific article published on 29 January 2015

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Evidence That in Uncontrolled Diabetes, Hyperglucagonemia Is Required for Ketosis but Not for Increased Hepatic Glucose Production or Hyperglycemia. (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Thomas H Meek

1

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Mauricio D Dorfman

2

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Miles E Matsen

3

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Jonathan D Fischer

4

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Alexis Cubelo

5

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Monica R Kumar

6

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Gerald J Taborsky

7

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Gregory J Morton

8

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

language of work or name

0 references

publication date

29 January 2015

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

64

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

7

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

2376-2387

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Quantification of the glycemic response to microdoses of subcutaneous glucagon at varying insulin levels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Role of glucagon-like peptide-1 analogue versus amylin as an adjuvant therapy in type 1 diabetes in a closed loop setting with ePID algorithm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Leptin reverses diabetes by suppression of the hypothalamic-pituitary-adrenal axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Ketone bodies as signaling metabolites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Glucagon-induced acetylation of Foxa2 regulates hepatic lipid metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Metabolic manifestations of insulin deficiency do not occur without glucagon action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Potential role of non-insulin adjunct therapy in Type 1 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Glucagonocentric restructuring of diabetes: a pathophysiologic and therapeutic makeover

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Review of the therapeutic uses of liraglutide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Liraglutide for the treatment of type 2 diabetes: a clinical update

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

GLP-1 and energy balance: an integrated model of short-term and long-term control

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Four weeks of treatment with liraglutide reduces insulin dose without loss of glycemic control in type 1 diabetic patients with and without residual beta-cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Glucagon receptor knockout prevents insulin-deficient type 1 diabetes in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Leptin activates a novel CNS mechanism for insulin-independent normalization of severe diabetic hyperglycemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Glucagon-like peptide analogues for type 2 diabetes mellitus: systematic review and meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

The metabolic actions of glucagon revisited

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Liraglutide: the therapeutic promise from animal models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Leptin therapy improves insulin-deficient type 1 diabetes by CNS-dependent mechanisms in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Leptin deficiency causes insulin resistance induced by uncontrolled diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Making insulin-deficient type 1 diabetic rodents thrive without insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Foxa2 regulates lipid metabolism and ketogenesis in the liver during fasting and in diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Lower blood glucose, hyperglucagonemia, and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Nuclear magnetic resonance studies of hepatic glucose metabolism in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Evidence that elevated plasma corticosterone levels are the cause of reduced hypothalamic corticotrophin-releasing hormone gene expression in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Central administration of GLP-1-(7-36) amide inhibits food and water intake in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Role of glucagon in maintenance of euglycemia in fed and fasted rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Glucagon activates mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in vivo by decreasing the extent of succinylation of the enzyme

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Regulation of the expression of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene. Its role in the control of ketogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Importance of hypoglycemia-induced glucose production during isolated glucagon deficiency

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

12 July 2018

Liraglutide as additional treatment for type 1 diabetes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

25 September 2018

Marked and rapid decreases of circulating leptin in streptozotocin diabetic rats: reversal by insulin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477352

25 September 2018

Glucagon: Role in the Hyperglycemia of Diabetes Mellitus

1 reference

https://pubmed.ncbi.nlm.nih.gov/25633417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low plasma leptin levels contribute to diabetic hyperphagia in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25633417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon

1 reference

https://pubmed.ncbi.nlm.nih.gov/25633417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fibroblast growth factor 21 (FGF21) and glucagon-like peptide 1 contribute to diabetes resistance in glucagon receptor-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/25633417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunoneutralization of endogenous glucagon with monoclonal glucagon antibody normalizes hyperglycaemia in moderately streptozotocin-diabetic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/25633417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential time course of glucagon's effect on glycogenolysis and gluconeogenesis in the conscious dog

1 reference

https://pubmed.ncbi.nlm.nih.gov/25633417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperglucagonemia and its suppression. Importance in the metabolic control of diabetes

1 reference

https://pubmed.ncbi.nlm.nih.gov/25633417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Studies of the development of diabetic ketosis in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/25633417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hyperglucagonemia in diabetic ketoacidosis. Its prevalence and significance

1 reference

https://pubmed.ncbi.nlm.nih.gov/25633417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a Major Role for Glucagon in Regulation of Plasma Glucose in Conscious, Nondiabetic, and Alloxan-Induced Diabetic Rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/25633417

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2337/DB14-1562

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

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