(Q35770603)

10 August 2017

title

The telomerase essential N-terminal domain promotes DNA synthesis by stabilizing short RNA-DNA hybrids (English)

1 reference

10 August 2017

Benjamin M Akiyama

1

1 reference

10 August 2017

Joseph W Parks

series ordinal

2

1 reference

10 August 2017

Michael D Stone

series ordinal

3

1 reference

10 August 2017

language of work or name

English

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publication date

4 May 2015

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10 August 2017

published in

Nucleic Acids Research

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10 August 2017

volume

43

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10 August 2017

issue

11

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10 August 2017

page(s)

5537-5549

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Creative Commons Attribution 4.0 International

10 August 2017

copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4477650/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Human telomerase specialization for repeat synthesis by unique handling of primer-template duplex

27 July 2018

1 reference

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The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis

27 July 2018

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RNA/DNA hybrid binding affinity determines telomerase template-translocation efficiency

27 July 2018

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Human telomerase domain interactions capture DNA for TEN domain-dependent processive elongation

27 July 2018

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Direct involvement of the TEN domain at the active site of human telomerase

27 July 2018

1 reference

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Telomerase: an RNP enzyme synthesizes DNA.

27 July 2018

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A single-molecule assay for telomerase structure-function analysis

27 July 2018

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Human telomerase reverse transcriptase (hTERT) Q169 is essential for telomerase function in vitro and in vivo

27 July 2018

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How shelterin protects mammalian telomeres

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Mutation in TERT separates processivity from anchor-site function

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Dyskeratosis congenita: the diverse clinical presentation of mutations in the telomerase complex

27 July 2018

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High-resolution physical and functional mapping of the template adjacent DNA binding site in catalytically active telomerase

27 July 2018

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Characterization of physical and functional anchor site interactions in human telomerase

27 July 2018

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Analysis of single-molecule FRET trajectories using hidden Markov modeling

27 July 2018

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Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase

27 July 2018

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A physical and functional constituent of telomerase anchor site

27 July 2018

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Tetrahymena telomerase is active as a monomer

27 July 2018

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27 July 2018

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27 July 2018

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Extension of life-span by introduction of telomerase into normal human cells

27 July 2018

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The anchor site of telomerase from Euplotes aediculatus revealed by photo-cross-linking to single- and double-stranded DNA primers

27 July 2018

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Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

27 July 2018

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27 July 2018

Telomerase is processive

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477650

Roles of telomerase reverse transcriptase N-terminal domain in assembly and activity of Tetrahymena telomerase holoenzyme

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477650

Assembly of complex RNAs by splinted ligation

25 September 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477650

Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477650

Telomerase recognizes its template by using an adjacent RNA motif

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477650

Functional multimerization of human telomerase requires an RNA interaction domain in the N terminus of the catalytic subunit

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4477650

Tetrahymena telomerase catalyzes nucleolytic cleavage and nonprocessive elongation

25 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25940626

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1093/NAR/GKV406

1 reference

10 August 2017

1 reference

10 August 2017

1 reference