(Q35779715)

10 August 2017

Molecular mechanisms of leukemogenesis by AML1/EVI-1. (English)

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10 August 2017

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Kinuko Mitani

1

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PubMed ID

15156182

10 August 2017

language of work or name

English

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publication date

1 May 2004

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10 August 2017

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10 August 2017

23

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10 August 2017

4263-4269

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10 August 2017

24

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PubMed ID

15156182

describes a project that uses

10 August 2017

SKH1

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exact match

https://scigraph.springernature.com/pub.10.1038/sj.onc.1207777

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cites work

Leukaemia/Drosophila homology

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

Absence of fetal liver hematopoiesis in mice deficient in transcriptional coactivator core binding factor beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

Dimerization with PEBP2beta protects RUNX1/AML1 from ubiquitin-proteasome-mediated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

The t(3;21) fusion product, AML1/Evi-1 blocks AML1-induced transactivation by recruiting CtBP.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

Interaction and functional cooperation of the leukemia-associated factors AML1 and p300 in myeloid cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

The evi-1 oncoprotein inhibits c-Jun N-terminal kinase and prevents stress-induced cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

Growth inhibition of leukaemic cells carrying the t(3;21) by the AML1/EVI-1-specific antisense oligonucleotide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

PEBP2/PEA2 represents a family of transcription factors homologous to the products of the Drosophila runt gene and the human AML1 gene

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

Differential requirements for Runx proteins in CD4 repression and epigenetic silencing during T lymphocyte development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1207777

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1207777

1 reference

10 August 2017

1 reference

PubMed ID

15156182