(Q35784588)

English

PCB153 reduces telomerase activity and telomere length in immortalized human skin keratinocytes (HaCaT) but not in human foreskin keratinocytes (NFK)

scientific article published on 22 December 2011

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

PCB153 reduces telomerase activity and telomere length in immortalized human skin keratinocytes (HaCaT) but not in human foreskin keratinocytes (NFK) (English)

1 reference

Europe PubMed Central

10 August 2017

telomere length

0 references

1 reference

based on heuristic

inferred from title

author name string

P K Senthilkumar

1

1 reference

Europe PubMed Central

10 August 2017

L W Robertson

2

1 reference

Europe PubMed Central

10 August 2017

G Ludewig

3

1 reference

Europe PubMed Central

10 August 2017

publication date

22 December 2011

1 reference

Europe PubMed Central

10 August 2017

Toxicology and Applied Pharmacology

1 reference

Europe PubMed Central

10 August 2017

259

1 reference

Europe PubMed Central

10 August 2017

1

1 reference

Europe PubMed Central

10 August 2017

115-123

1 reference

Europe PubMed Central

10 August 2017

Airborne polychlorinated biphenyls (PCBs) reduce telomerase activity and shorten telomere length in immortal human skin keratinocytes (HaCat)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288560

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The role of telomeres in the ageing of human skin.

1 reference

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Telomerase deficiency impairs glucose metabolism and insulin secretion

1 reference

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Polychlorinated biphenyl induced ROS signaling delays the entry of quiescent human breast epithelial cells into the proliferative cycle.

1 reference

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Tumor cell redox state and mitochondria at the center of the non-canonical activity of telomerase reverse transcriptase.

1 reference

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Telomerase deficiency and cancer susceptibility syndromes

1 reference

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Shorter telomere length in peripheral blood lymphocytes of workers exposed to polycyclic aromatic hydrocarbons

1 reference

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Polychlorinated-biphenyl-induced oxidative stress and cytotoxicity can be mitigated by antioxidants after exposure.

1 reference

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Catalase ameliorates polychlorinated biphenyl-induced cytotoxicity in nonmalignant human breast epithelial cells

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Metabolic Activation of PCBs to Carcinogens in Vivo - A Review.

1 reference

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ORAL ADMINISTRATION OF PCBs INDUCES PROINFLAMMATORY AND PROMETASTATIC RESPONSES.

1 reference

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Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts.

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1 reference

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12 July 2018

Telomeres: prognostic markers for solid tumors

1 reference

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12 July 2018

Major cutbacks at chromosome ends

1 reference

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Mutations in the reverse transcriptase component of telomerase (TERT) in patients with bone marrow failure

1 reference

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Organochlorines and risk of prostate cancer

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12 July 2018

Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.

1 reference

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Global accounting of PCBs in the continental shelf sediments

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Complex roles for telomeres and telomerase in breast carcinogenesis

1 reference

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12 July 2018

SYBR Green real-time telomeric repeat amplification protocol for the rapid quantification of telomerase activity

1 reference

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12 July 2018

Oxidative stress shortens telomeres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3288560

12 July 2018

Telomere measurement by quantitative PCR

1 reference

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12 July 2018

Replicative aging, telomeres, and oxidative stress

1 reference

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Site-specific DNA damage at the GGG sequence by UVA involves acceleration of telomere shortening

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Production of DNA strand breaks in vitro and reactive oxygen species in vitro and in HL-60 cells by PCB metabolites.

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Sequence-specific DNA cleavage by Fe2+-mediated fenton reactions has possible biological implications

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Assessing the cancer risk from environmental PCBs

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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Cancer mortality in workers exposed to phenoxy herbicides, chlorophenols, and dioxins: an expanded and updated international cohort study

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Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP).

1 reference

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Telomerase activity in the regenerative basal layer of the epidermis inhuman skin and in immortal and carcinoma-derived skin keratinocytes

1 reference

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Telomerase activation in mouse mammary tumors: lack of detectable telomere shortening and evidence for regulation of telomerase RNA with cell proliferation

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1 reference

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1 reference

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Effect of PCB153 on BaP-induced genotoxicity in HepG2 cells via modulation of metabolic enzymes.

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NTP technical report on the toxicology and carcinogenesis studies of 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in female Harlan Sprague-Dawley rats (Gavage studies).

1 reference

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Increased telomerase activity in mouse skin premalignant progression.

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1 reference

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Oxidative DNA damage induced by activation of polychlorinated biphenyls (PCBs): implications for PCB-induced oxidative stress in breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/22210444

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Role of alpha-tocopherol on antioxidant status in liver, lung and kidney of PCB exposed male albino rats

1 reference

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inferred from PubMed ID database lookup

Telomerase modulates expression of growth-controlling genes and enhances cell proliferation

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https://pubmed.ncbi.nlm.nih.gov/22210444

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inferred from PubMed ID database lookup

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Autopsy of patients with yusho

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inferred from PubMed ID database lookup

Site-specific DNA damage at GGG sequence by oxidative stress may accelerate telomere shortening

1 reference

https://pubmed.ncbi.nlm.nih.gov/22210444

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.TAAP.2011.12.015

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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