(Q35785306)

English

Enzymatic activities of human cytomegalovirus maturational protease assemblin and its precursor (pPR, pUL80a) are comparable: [corrected] maximal activity of pPR requires self-interaction through its scaffolding domain

scientific article published on 7 February 2007

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scholarly article

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Europe PubMed Central

PubMed publication ID

10 August 2017

Enzymatic activities of human cytomegalovirus maturational protease assemblin and its precursor (pPR, pUL80a) are comparable: [corrected] maximal activity of pPR requires self-interaction through its scaffolding domain (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Cytomegalovirus

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author name string

Edward J Brignole

1

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Wade Gibson

2

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

language of work or name

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publication date

7 February 2007

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Journal of Virology

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Europe PubMed Central

PubMed publication ID

10 August 2017

81

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Europe PubMed Central

PubMed publication ID

10 August 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

4091-4103

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

The amino-conserved domain of human cytomegalovirus UL80a proteins is required for key interactions during early stages of capsid formation and virus production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866128

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One functional switch mediates reversible and irreversible inactivation of a herpesvirus protease.

1 reference

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27 July 2018

Cleavage of human cytomegalovirus protease pUL80a at internal and cryptic sites is not essential but enhances infectivity

1 reference

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27 July 2018

Chemical rescue of I-site cleavage in living cells and in vitro discriminates between the cytomegalovirus protease, assemblin, and its precursor, pUL80a

1 reference

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Maribavir (ViroPharma).

1 reference

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Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments.

1 reference

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The crystal structure of the Epstein-Barr virus protease shows rearrangement of the processed C terminus

1 reference

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27 July 2018

Cytomegalovirus assemblin (pUL80a): cleavage at internal site not essential for virus growth; proteinase absent from virions

1 reference

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Conformational change coupling the dimerization and activation of KSHV protease

1 reference

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Recent strategies in the development of new human cytomegalovirus inhibitors.

1 reference

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The herpesvirus proteases as targets for antiviral chemotherapy

1 reference

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Isolation of herpes simplex virus procapsids from cells infected with a protease-deficient mutant virus.

1 reference

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Second site mutations in the N-terminus of the major capsid protein (VP5) overcome a block at the maturation cleavage site of the capsid scaffold proteins of herpes simplex virus type 1.

1 reference

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Auto-inactivation by cleavage within the dimer interface of Kaposi's sarcoma-associated herpesvirus protease

1 reference

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Capsid structure of simian cytomegalovirus from cryoelectron microscopy: evidence for tegument attachment sites

1 reference

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Cytomegalovirus assembly protein precursor and proteinase precursor contain two nuclear localization signals that mediate their own nuclear translocation and that of the major capsid protein.

1 reference

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27 July 2018

Capsids are formed in a mutant virus blocked at the maturation site of the UL26 and UL26.5 open reading frames of herpes simplex virus type 1 but are not formed in a null mutant of UL38 (VP19C).

1 reference

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Assemblin, an essential herpesvirus proteinase

1 reference

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Human cytomegalovirus cell tropism and pathogenesis

1 reference

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Initial characterization of autoprocessing and active-center mutants of CMV proteinase

1 reference

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27 July 2018

Human cytomegalovirus capsid assembly protein precursor (pUL80.5) interacts with itself and with the major capsid protein (pUL86) through two different domains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866128

27 July 2018

Three-dimensional structure of human cytomegalovirus protease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1866128

27 July 2018

A new serine-protease fold revealed by the crystal structure of human cytomegalovirus protease

1 reference

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27 July 2018

Structure of the human cytomegalovirus protease catalytic domain reveals a novel serine protease fold and catalytic triad.

1 reference

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Cytomegalovirus assemblin: the amino and carboxyl domains of the proteinase form active enzyme when separately cloned and coexpressed in eukaryotic cells

1 reference

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27 July 2018

Separate functional domains of the herpes simplex virus type 1 protease: evidence for cleavage inside capsids

1 reference

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Stimulation of the herpes simplex virus type I protease by antichaeotrophic salts

1 reference

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Characterization of the protease and other products of amino-terminus-proximal cleavage of the herpes simplex virus 1 UL26 protein.

1 reference

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Expression and analysis of the human cytomegalovirus UL80-encoded protease: identification of autoproteolytic sites

1 reference

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In vitro activity of the herpes simplex virus type 1 protease with peptide substrates

1 reference

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Herpesvirus proteinase: site-directed mutagenesis used to study maturational, release, and inactivation cleavage sites of precursor and to identify a possible catalytic site serine and histidine.

1 reference

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Proteolytic activity of human cytomegalovirus UL80 protease cleavage site mutants

1 reference

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The protease of herpes simplex virus type 1 is essential for functional capsid formation and viral growth

1 reference

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Assembly of herpes simplex virus type 1 capsids using a panel of recombinant baculoviruses

1 reference

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Identification of the serine residue at the active site of the herpes simplex virus type 1 protease.

1 reference

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Human cytomegalovirus maturational proteinase: expression in Escherichia coli, purification, and enzymatic characterization by using peptide substrate mimics of natural cleavage sites

1 reference

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Assembly of herpes simplex virus (HSV) intermediate capsids in insect cells infected with recombinant baculoviruses expressing HSV capsid proteins

1 reference

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The size and symmetry of B capsids of herpes simplex virus type 1 are determined by the gene products of the UL26 open reading frame

1 reference

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In vitro proteolytic activity and active-site identification of the human cytomegalovirus protease.

1 reference

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Cytomegalovirus protein substrates are not cleaved by the herpes simplex virus type 1 proteinase

1 reference

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The effect of internal autocleavage on kinetic properties of the human cytomegalovirus protease catalytic domain

1 reference

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Human cytomegalovirus proteinase: candidate glutamic acid identified as third member of putative active-site triad

1 reference

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Release of the catalytic domain N(o) from the herpes simplex virus type 1 protease is required for viral growth

1 reference

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Identification and Characterization of a Herpes Simplex Virus Gene Product Required for Encapsidation of Virus DNA

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On the size of the active site in proteases. I. Papain

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1 reference

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1 reference

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1 reference

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Communication between the active sites and dimer interface of a herpesvirus protease revealed by a transition-state inhibitor

1 reference

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Characterization of the monomer-dimer equilibrium of human cytomegalovirus protease by kinetic methods

1 reference

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Current and potential therapies for the treatment of herpes-virus infections

1 reference

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New inhibitors of human cytomegalovirus (HCMV) on the horizon

1 reference

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Recombinant full-length human cytomegalovirus protease has lower activity than recombinant processed protease domain in purified enzyme and cell-based assays

1 reference

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Molecular mechanism for dimerization to regulate the catalytic activity of human cytomegalovirus protease

1 reference

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Novel vectors for co-expression of two proteins in E. coli

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Cytomegalovirus basic phosphoprotein (pUL32) binds to capsids in vitro through its amino one-third

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Herpesvirus proteases: targets for novel antiviral drugs

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Unique fold and active site in cytomegalovirus protease

1 reference

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Active human cytomegalovirus protease is a dimer.

1 reference

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Activity of two-chain recombinant human cytomegalovirus protease.

1 reference

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Design of fluorogenic peptide substrates for human cytomegalovirus protease based on structure-activity relationship studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and kinetic characterization of human cytomegalovirus assemblin

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dimerization of the human cytomegalovirus protease: kinetic and biochemical characterization of the catalytic homodimer

1 reference

https://pubmed.ncbi.nlm.nih.gov/17287260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.02821-06

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

ResearchGate publication ID

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