(Q35790974)

10 August 2017

Clinical and pathophysiological consequences of alterations in the microbiome in cirrhosis (English)

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10 August 2017

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Jane Macnaughtan

1

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PubMed ID

26416191

10 August 2017

Rajiv Jalan

series ordinal

2

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PubMed ID

26416191

10 August 2017

language of work or name

English

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publication date

29 September 2015

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The American Journal of Gastroenterology

10 August 2017

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10 August 2017

110

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10 August 2017

10

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10 August 2017

1399-410; quiz 1411

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Gastric permeability to sucrose is increased in portal hypertensive gastropathy.

10 August 2017

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12 December 2020

Comparison of the gut microbe profiles and numbers between patients with liver cirrhosis and healthy individuals

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12 December 2020

Effects of the adjunctive probiotic VSL#3 on portal haemodynamics in patients with cirrhosis and large varices: a randomized trial.

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12 December 2020

TLR4 enhances TGF-beta signaling and hepatic fibrosis

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12 December 2020

Antibiotic prophylaxis for the prevention of bacterial infections in cirrhotic patients with gastrointestinal bleeding: a meta-analysis

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12 December 2020

NOD2 gene variants are a risk factor for culture-positive spontaneous bacterial peritonitis and monomicrobial bacterascites in cirrhosis.

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12 December 2020

Gut dysbiosis in acute-on-chronic liver failure and its predictive value for mortality

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12 December 2020

Modulation of the metabiome by rifaximin in patients with cirrhosis and minimal hepatic encephalopathy

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12 December 2020

Comparison of rifaximin and lactitol in the treatment of acute hepatic encephalopathy: results of a randomized, double-blind, double-dummy, controlled clinical trial

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12 December 2020

Ammonia and the neutrophil in the pathogenesis of hepatic encephalopathy in cirrhosis

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12 December 2020

Role of Kupffer cells in host defense and liver disease

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12 December 2020

Characterization of fecal microbial communities in patients with liver cirrhosis.

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12 December 2020

Mechanisms of action of probiotics: recent advances

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12 December 2020

Abnormal fecal microbiota community and functions in patients with hepatitis B liver cirrhosis as revealed by a metagenomic approach

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12 December 2020

Toll-like receptors in liver disease

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12 December 2020

Small bowel bacterial overgrowth in patients with alcoholic cirrhosis

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12 December 2020

[Effect of administration of Escherichia coli Nissle (Mutaflor) on intestinal colonisation, endo-toxemia, liver function and minimal hepatic encephalopathy in patients with liver cirrhosis]

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12 December 2020

Bacteriocolonic pathway for ethanol oxidation: characteristics and implications

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12 December 2020

Efficacy of lactulose in cirrhotic patients with subclinical hepatic encephalopathy

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12 December 2020

Large-scale survey of gut microbiota associated with MHE Via 16S rRNA-based pyrosequencing

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12 December 2020

Intestinal microflora in patients with liver cirrhosis

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12 December 2020

Translocation of Certain Indigenous Bacteria from the Gastrointestinal Tract to the Mesenteric Lymph Nodes and Other Organs in a Gnotobiotic Mouse Model

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12 December 2020

Altered profile of human gut microbiome is associated with cirrhosis and its complications

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12 December 2020

Evidence of neutrophil functional defect despite inflammation in stable cirrhosis.

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12 December 2020

Influence of portal pressure change on intestinal permeability in patients with portal hypertension

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12 December 2020

Secondary prophylaxis of hepatic encephalopathy in cirrhosis: an open-label, randomized controlled trial of lactulose, probiotics, and no therapy

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12 December 2020

Bifidobacterium longum with fructo-oligosaccharide (FOS) treatment in minimal hepatic encephalopathy: a randomized, double-blind, placebo-controlled study.

1 reference

12 December 2020

The intestinal flora and bacterial infection in cirrhosis

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12 December 2020

Oral, capsulized, frozen fecal microbiota transplantation for relapsing Clostridium difficile infection.

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12 December 2020

Altered monocyte responses to defined TLR ligands in patients with primary biliary cirrhosis

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12 December 2020

AST-120 (spherical carbon adsorbent) lowers ammonia levels and attenuates brain edema in bile duct-ligated rats

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12 December 2020

Gut microbiota regulates bile acid metabolism by reducing the levels of tauro-beta-muricholic acid, a naturally occurring FXR antagonist

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12 December 2020

Treatment of hepatic encephalopathy with metronidazole

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12 December 2020

Hepatic dimethylarginine-dimethylaminohydrolase1 is reduced in cirrhosis and is a target for therapy in portal hypertension.

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12 December 2020

Synbiotic modulation of gut flora: effect on minimal hepatic encephalopathy in patients with cirrhosis

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12 December 2020

The intestinal microbiota and microenvironment in liver

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12 December 2020

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease.

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12 December 2020

Probiotics for patients with compensated liver cirrhosis: a double-blind placebo-controlled study

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12 December 2020

Microbiota modification with probiotics induces hepatic bile acid synthesis via downregulation of the Fxr-Fgf15 axis in mice.

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12 December 2020

Randomised clinical trial: Lactobacillus GG modulates gut microbiome, metabolome and endotoxemia in patients with cirrhosis

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12 December 2020

Toll-like receptors and their role in gastrointestinal disease.

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12 December 2020

Lactulose improves psychometric testing in cirrhotic patients with subclinical encephalopathy

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12 December 2020

Comparison between neomycin and lactulose in 173 patients with hepatic encephalopathy: a randomized clinical study

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12 December 2020

Muricholic bile acids are potent regulators of bile acid synthesis via a positive feedback mechanism

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12 December 2020

Acute-on-Chronic Liver Failure Is a Distinct Syndrome That Develops in Patients With Acute Decompensation of Cirrhosis

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12 December 2020

Intestinal microbiota was assessed in cirrhotic patients with hepatitis B virus infection. Intestinal microbiota of HBV cirrhotic patients

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12 December 2020

Neomycin in the treatment of hepatic coma

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12 December 2020

Intravenous endotoxin suppresses the cytokine response of peripheral blood mononuclear cells of healthy humans.

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12 December 2020

Primary prophylaxis of spontaneous bacterial peritonitis delays hepatorenal syndrome and improves survival in cirrhosis

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12 December 2020

Endotoxemia contributes to the immune paralysis in patients with cirrhosis

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12 December 2020

Systemic inflammatory response exacerbates the neuropsychological effects of induced hyperammonemia in cirrhosis.

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12 December 2020

Jejunal microflora in patients with chronic alcohol abuse.

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12 December 2020

Obesity, metabolic syndrome, and microbiota: multiple interactions

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12 December 2020

Small intestinal motility disturbances and bacterial overgrowth in patients with liver cirrhosis and portal hypertension

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12 December 2020

Small intestine dysmotility and bacterial overgrowth in cirrhotic patients with spontaneous bacterial peritonitis

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12 December 2020

Proton pump inhibitor therapy does not increase the incidence of spontaneous bacterial peritonitis in cirrhosis: a multicenter prospective study

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12 December 2020

Salivary microbiota reflects changes in gut microbiota in cirrhosis with hepatic encephalopathy

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12 December 2020

A randomized double blind placebo controlled trial of probiotics in minimal hepatic encephalopathy

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12 December 2020

The effect of selective intestinal decontamination on the hyperdynamic circulatory state in cirrhosis. A randomized trial

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12 December 2020

Cirrhosis-associated immune dysfunction: distinctive features and clinical relevance

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12 December 2020

Nucleotide-binding oligomerization domain containing 2 (NOD2) variants are genetic risk factors for death and spontaneous bacterial peritonitis in liver cirrhosis

1 reference

12 December 2020

Antibiotic prophylaxis after endoscopic therapy prevents rebleeding in acute variceal hemorrhage: a randomized trial

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12 December 2020

Toll-like receptor-4 signaling and Kupffer cells play pivotal roles in the pathogenesis of non-alcoholic steatohepatitis

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12 December 2020

Acid-suppressive therapy is associated with spontaneous bacterial peritonitis in cirrhotic patients: a meta-analysis.

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12 December 2020

Long-term administration of rifaximin improves the prognosis of patients with decompensated alcoholic cirrhosis

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12 December 2020

Double-blind, double-dummy comparison between treatment with rifaximin and lactulose in patients with medium to severe degree hepatic encephalopathy.

1 reference

12 December 2020

Intestinal permeability in patients with chronic liver diseases: Its relationship with the aetiology and the entity of liver damage.

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12 December 2020

Modulation of the fecal bile acid profile by gut microbiota in cirrhosis

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12 December 2020

Endotoxemia produces coma and brain swelling in bile duct ligated rats

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12 December 2020

Clinical efficacy of lactulose in cirrhotic patients with and without subclinical hepatic encephalopathy

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12 December 2020

Tumour necrosis factor-alpha expression by activated monocytes and altered T-cell homeostasis in ascitic alcoholic cirrhosis: amelioration with norfloxacin

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12 December 2020

Alterations of the human gut microbiome in liver cirrhosis

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12 December 2020

Norfloxacin vs ceftriaxone in the prophylaxis of infections in patients with advanced cirrhosis and hemorrhage.

1 reference

12 December 2020

Norfloxacin prevents spontaneous bacterial peritonitis recurrence in cirrhosis: results of a double-blind, placebo-controlled trial

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12 December 2020

The liver-brain axis in liver failure: neuroinflammation and encephalopathy

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12 December 2020

Long-term effects of Enterococcus faecium SF68 versus lactulose in the treatment of patients with cirrhosis and grade 1-2 hepatic encephalopathy.

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12 December 2020

Acute binge drinking increases serum endotoxin and bacterial DNA levels in healthy individuals

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12 December 2020

Toll-like receptor (TLR) 2 promoter and intron 2 polymorphisms are associated with increased risk for spontaneous bacterial peritonitis in liver cirrhosis

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12 December 2020

Nitrate reduction to nitrite, nitric oxide and ammonia by gut bacteria under physiological conditions

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12 December 2020

Serum and ascitic fluid bacterial DNA: a new independent prognostic factor in noninfected patients with cirrhosis

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12 December 2020

Rifaximin treatment in hepatic encephalopathy

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12 December 2020

A randomized, double-blind, controlled trial comparing rifaximin plus lactulose with lactulose alone in treatment of overt hepatic encephalopathy.

1 reference

12 December 2020

Infection, coagulation, and variceal bleeding in cirrhosis

1 reference

12 December 2020

Neomycin-sorbitol and lactulose in the treatment of acute portal-systemic encephalopathy. A controlled, double-blind clinical trial

1 reference

12 December 2020

Increased lipopolysaccharide binding protein in cirrhotic patients with marked immune and hemodynamic derangement.

1 reference

12 December 2020

Patients with acute on chronic liver failure display "sepsis-like" immune paralysis

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12 December 2020

Oral propranolol decreases intestinal permeability in patients with cirrhosis: another protective mechanism against bleeding?

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12 December 2020

Colonic mucosal microbiome differs from stool microbiome in cirrhosis and hepatic encephalopathy and is linked to cognition and inflammation

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12 December 2020

Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats

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12 December 2020

Obeticholic acid, a farnesoid X receptor agonist, improves portal hypertension by two distinct pathways in cirrhotic rats

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12 December 2020

Norfloxacin prevents bacterial infection in cirrhotics with gastrointestinal hemorrhage

1 reference

12 December 2020

A randomized controlled trial comparing lactulose, probiotics, and L-ornithine L-aspartate in treatment of minimal hepatic encephalopathy.

1 reference

12 December 2020

Gut flora and hepatic encephalopathy in patients with cirrhosis

1 reference

12 December 2020

Lactitol versus lactulose in the treatment of acute portal systemic encephalopathy (PSE)

1 reference

12 December 2020

Probiotics prevent hepatic encephalopathy in patients with cirrhosis: a randomized controlled trial

1 reference

12 December 2020

Intestinal decontamination inhibits TLR4 dependent fibronectin-mediated cross-talk between stellate cells and endothelial cells in liver fibrosis in mice

1 reference

12 December 2020

Prevention of acute kidney injury in a rodent model of cirrhosis following selective gut decontamination is associated with reduced renal TLR4 expression

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12 December 2020

Neutrophil dysfunction in alcoholic hepatitis superimposed on cirrhosis is reversible and predicts the outcome.

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12 December 2020

Mortality associated with proton pump inhibitors in cirrhotic patients with spontaneous bacterial peritonitis

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12 December 2020

Splanchnic endotoxin levels in cirrhotic rats induced by carbon tetrachloride.

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12 December 2020

Systems biology analysis of omeprazole therapy in cirrhosis demonstrates significant shifts in gut microbiota composition and function

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12 December 2020

[Bacterial DNA in patients with cirrhosis and sterile ascites. Its role as a marker of bacterial translocation and prognostic tool]

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12 December 2020

A novel mechanism for gut barrier dysfunction by dietary fat: epithelial disruption by hydrophobic bile acids

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12 December 2020

Mesenteric Th1 polarization and monocyte TNF-alpha production: first steps to systemic inflammation in rats with cirrhosis

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12 December 2020

The molecules: mechanisms of arterial vasodilatation observed in the splanchnic and systemic circulation in portal hypertension

1 reference

12 December 2020

Lactitol versus lactulose in the treatment of chronic hepatic encephalopathy. A double-blind, randomised, cross-over study

1 reference

12 December 2020

Rifaximin improves systemic hemodynamics and renal function in patients with alcohol-related cirrhosis and ascites

1 reference

12 December 2020

Cirrhotic rats with bacterial translocation have higher incidence and severity of hepatopulmonary syndrome

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12 December 2020

beta-Blockers protect against spontaneous bacterial peritonitis in cirrhotic patients: a meta-analysis.

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12 December 2020

Intestinal permeability in cirrhotic patients with and without spontaneous bacterial peritonitis: is the ring closed?

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12 December 2020

Cirrhosis, bile acids and gut microbiota: unraveling a complex relationship.

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12 December 2020

Role of Toll-like receptors 2, 4, and 9 in mediating neutrophil dysfunction in alcoholic hepatitis

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12 December 2020

Abnormalities of neutrophil phagocytosis, intracellular killing and metabolic activity in alcoholic cirrhosis and hepatitis

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12 December 2020

Linkage of gut microbiome with cognition in hepatic encephalopathy

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12 December 2020

Beta-blockers cause paracentesis-induced circulatory dysfunction in patients with cirrhosis and refractory ascites: A cross-over study

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12 December 2020

Changes in gut bacterial populations and their translocation into liver and ascites in alcoholic liver cirrhotics

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12 December 2020

Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice.

1 reference

12 December 2020

Lactulose in the treatment of chronic portal-systemic encephalopathy. A double-blind clinical trial.

1 reference

12 December 2020

Increasing frequency of gram-positive cocci and gram-negative multidrug-resistant bacteria in spontaneous bacterial peritonitis

1 reference

12 December 2020

Norfloxacin treatment for clinically significant portal hypertension: results of a randomised double-blind placebo-controlled crossover trial.

1 reference

12 December 2020

Identifiers

DOI

10.1038/AJG.2015.313

1 reference

10 August 2017

1 reference

PubMed ID

26416191