(Q35794287)

English

Relative replication fitness of efavirenz-resistant mutants of HIV-1: correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V.

scientific article published on 21 June 2006

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Relative replication fitness of efavirenz-resistant mutants of HIV-1: correlation with frequency during clinical therapy and evidence of compensation for the reduced fitness of K103N + L100I by the nucleoside resistance mutation L74V. (English)

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

1 reference

based on heuristic

inferred from title

author name string

Christine E Koval

1

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Carrie Dykes

2

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Jiong Wang

3

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

Lisa M Demeter

4

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

language of work or name

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publication date

21 June 2006

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Europe PubMed Central

PubMed publication ID

10 August 2017

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

353

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

184-192

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

The HIV-1 reverse transcriptase mutants G190S and G190A, which confer resistance to non-nucleoside reverse transcriptase inhibitors, demonstrate reductions in RNase H activity and DNA synthesis from tRNA(Lys, 3) that correlate with reductions in rep

1 reference

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Relative replicative fitness of human immunodeficiency virus type 1 mutants resistant to enfuvirtide (T-20).

1 reference

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The Y181C substitution in 3'-azido-3'-deoxythymidine-resistant human immunodeficiency virus, type 1, reverse transcriptase suppresses the ATP-mediated repair of the 3'-azido-3'-deoxythymidine 5'-monophosphate-terminated primer

1 reference

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Amino acid substitutions at position 190 of human immunodeficiency virus type 1 reverse transcriptase increase susceptibility to delavirdine and impair virus replication

1 reference

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The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance

1 reference

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Genotypic correlates of phenotypic resistance to efavirenz in virus isolates from patients failing nonnucleoside reverse transcriptase inhibitor therapy

1 reference

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Mutants of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase resistant to nonnucleoside reverse transcriptase inhibitors demonstrate altered rates of RNase H cleavage that correlate with HIV-1 replication fitness in cell culture

1 reference

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Human immunodeficiency virus type 1 mutations selected in patients failing efavirenz combination therapy

1 reference

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A novel phenotypic drug susceptibility assay for human immunodeficiency virus type 1

1 reference

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27 July 2018

The P236L delavirdine-resistant human immunodeficiency virus type 1 mutant is replication defective and demonstrates alterations in both RNA 5'-end- and DNA 3'-end-directed RNase H activities

1 reference

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27 July 2018

A mutation at position 190 of human immunodeficiency virus type 1 reverse transcriptase interacts with mutations at positions 74 and 75 via the template primer

1 reference

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Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme.

1 reference

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27 July 2018

1 reference

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27 July 2018

Standardized peripheral blood mononuclear cell culture assay for determination of drug susceptibilities of clinical human immunodeficiency virus type 1 isolates.

1 reference

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27 July 2018

HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy

1 reference

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27 July 2018

Susceptibilities of human immunodeficiency virus type 1 enzyme and viral variants expressing multiple resistance-engendering amino acid substitutions to reserve transcriptase inhibitors

1 reference

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27 July 2018

Interactions between drug resistance mutations in human immunodeficiency virus type 1 reverse transcriptase

1 reference

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Nevirapine resistance mutations of human immunodeficiency virus type 1 selected during therapy

1 reference

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Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors

1 reference

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Quantitation of relative fitness and great adaptability of clonal populations of RNA viruses

1 reference

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27 July 2018

3'-Azido-3'-deoxythymidine resistance suppressed by a mutation conferring human immunodeficiency virus type 1 resistance to nonnucleoside reverse transcriptase inhibitors

1 reference

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27 July 2018

HIV-1 reverse transcriptase mutants resistant to nonnucleoside reverse transcriptase inhibitors do not adversely affect DNA synthesis: pre-steady-state and steady-state kinetic studies.

1 reference

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25 September 2018

Modeling and estimation of replication fitness of human immunodeficiency virus type 1 in vitro experiments by using a growth competition assay

1 reference

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25 September 2018

Genetic correlates of efavirenz hypersusceptibility

1 reference

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Treatment for adult HIV infection: 2004 recommendations of the International AIDS Society-USA Panel.

1 reference

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HIV-1 reverse transcriptase and protease resistance mutations selected during 16-72 weeks of therapy in isolates from antiretroviral therapy-experienced patients receiving abacavir/efavirenz/amprenavir in the CNA2007 study

1 reference

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Phenotypic hypersusceptibility to non-nucleoside reverse transcriptase inhibitors in treatment-experienced HIV-infected patients: impact on virological response to efavirenz-based therapy

1 reference

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25 September 2018

Estimating relative fitness in viral competition experiments.

1 reference

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25 September 2018

Identifiers

10.1016/J.VIROL.2006.05.021

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

10 August 2017

ResearchGate publication ID

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