(Q35794379)

10 August 2017

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title

Hepatocyte growth factor in kidney fibrosis: therapeutic potential and mechanisms of action (English)

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10 August 2017

Youhua Liu

1

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10 August 2017

publication date

1 July 2004

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American Journal of Physiology - Renal Physiology

10 August 2017

published in

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10 August 2017

volume

287

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10 August 2017

issue

1

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10 August 2017

page(s)

F7-16

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The five amino acid-deleted isoform of hepatocyte growth factor promotes carcinogenesis in transgenic mice.

10 August 2017

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Counteractive effects of HGF on PDGF-induced mesangial cell proliferation in a rat model of glomerulonephritis

21 January 2018

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TGF-beta in kidney fibrosis: a target for gene therapy

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Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease

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TGF-beta signaling in renal disease

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Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy

21 January 2018

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Invasive growth: from development to metastasis

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Regression of advanced diabetic nephropathy by hepatocyte growth factor gene therapy in rats

21 January 2018

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Hepatocyte growth factor antagonizes the profibrotic action of TGF-beta1 in mesangial cells by stabilizing Smad transcriptional corepressor TGIF

21 January 2018

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Transforming growth factor-beta1 potentiates renal tubular epithelial cell death by a mechanism independent of Smad signaling

21 January 2018

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Thrombospondin-1 is a major activator of TGF-beta in fibrotic renal disease in the rat in vivo.

21 January 2018

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The role of growth factors on renal tubular cells submitted to hypoxia and deprived of glucose.

21 January 2018

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Hepatocyte growth factor ameliorates progression of interstitial fibrosis in rats with established renal injury

21 January 2018

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Molecular basis of renal fibrosis

21 January 2018

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Transforming growth factor-beta regulates tubular epithelial-myofibroblast transdifferentiation in vitro

21 January 2018

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Prevention of acute ischemic renal failure by targeted delivery of growth factors to the proximal tubule in transgenic mice: the efficacy of parathyroid hormone-related protein and hepatocyte growth factor

21 January 2018

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Hepatocyte growth factor, but not insulin-like growth factor I, protects podocytes against cyclosporin A-induced apoptosis

21 January 2018

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Hepatocyte growth factor gene therapy retards the progression of chronic obstructive nephropathy

21 January 2018

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Hepatocyte growth factor overexpression in the islet of transgenic mice increases beta cell proliferation, enhances islet mass, and induces mild hypoglycemia.

21 January 2018

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Beneficial Effects of Estrogens on Indices of Renal Damage in Uninephrectomized SHRsp Rats

21 January 2018

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Evidence that fibroblasts derive from epithelium during tissue fibrosis

21 January 2018

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Epithelial-mesenchymal transition and its implications for fibrosis

21 January 2018

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Hepatocyte growth factor prevents acute renal failure and accelerates renal regeneration in mice

21 January 2018

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Adiponectin is not altered with exercise training despite enhanced insulin action

21 January 2018

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Hepatocyte growth factor regulates proteoglycan synthesis in interstitial fibroblasts

21 January 2018

1 reference

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A mechanism of repression of TGFbeta/ Smad signaling by oncogenic Ras

21 January 2018

1 reference

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Keratinocyte expression of transgenic hepatocyte growth factor affects melanocyte development, leading to dermal melanocytosis.

21 January 2018

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Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes

21 January 2018

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Role for integrin-linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis

21 January 2018

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Therapeutic role of TGF-beta-neutralizing antibody in mouse cyclosporin A nephropathy: morphologic improvement associated with functional preservation

21 January 2018

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Epithelial to mesenchymal transition in renal fibrogenesis: pathologic significance, molecular mechanism, and therapeutic intervention

21 January 2018

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Hepatocyte growth factor and the kidney

21 January 2018

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Modulation of hepatocyte growth factor gene expression by estrogen in mouse ovary

21 January 2018

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Hepatocyte growth factor protects renal epithelial cells from apoptotic cell death

21 January 2018

1 reference

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Epidermal growth factor signaling via Ras controls the Smad transcriptional co-repressor TGIF.

21 January 2018

1 reference

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Divergent effects of low versus high dose anti-TGF-beta antibody in puromycin aminonucleoside nephropathy in rats

21 January 2018

1 reference

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A vitamin D analog ameliorates glomerular injury on rat glomerulonephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

How cells read TGF-beta signals

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Hepatocyte growth factor prevents renal fibrosis and dysfunction in a mouse model of chronic renal disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Suppressions of chronic glomerular injuries and TGF-β1production by HGF in attenuation of murine diabetic nephropathy

21 January 2018

1 reference

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Hepatocyte growth factor prevents endothelial cell death through inhibition of bax translocation from cytosol to mitochondrial membrane

21 January 2018

1 reference

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Transgene-derived hepatocyte growth factor attenuates reactive renal fibrosis in aristolochic acid nephrotoxicity

21 January 2018

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How to make tubes: signaling by the Met receptor tyrosine kinase

21 January 2018

1 reference

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Targeted disruption of TGF-β1/Smad3 signaling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Apoptosis in podocytes induced by TGF-beta and Smad7

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

TGF-beta signal transduction and mesangial cell fibrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Effect of 1,25 (OH)2 vitamin D3 on glomerulosclerosis in subtotally nephrectomized rats

21 January 2018

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Mechanisms of TGF-beta signaling from cell membrane to the nucleus

21 January 2018

1 reference

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Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

In vivo gene transfer of hepatocyte growth factor to skeletal muscle prevents changes in rat kidneys after 5/6 nephrectomy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Regulation of cell proliferation by Smad proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Hepatocyte growth factor in renal failure: promise and reality

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Hepatocyte growth factor gene therapy and angiotensin II blockade synergistically attenuate renal interstitial fibrosis in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Hepatocyte growth factor suppresses renal interstitial myofibroblast activation and intercepts Smad signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Dissection of key events in tubular epithelial to myofibroblast transition and its implications in renal interstitial fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Potential role of hepatocyte growth factor in the maintenance of renal structure: anti-apoptotic action of HGF on epithelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

TGF-beta isoforms in renal fibrogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Urokinase receptor deficiency accelerates renal fibrosis in obstructive nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Sp1 and Sp3 transcription factors synergistically regulate HGF receptor gene expression in kidney

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Suppression of HGF receptor gene expression by oxidative stress is mediated through the interplay between Sp1 and Egr-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

Overview: combating diabetic nephropathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPRENAL.00451.2003

10.1152/AJPRENAL.00451.2003

21 January 2018

Identifiers

DOI

1 reference

10 August 2017

1 reference