(Q35805989)

10 August 2017

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title

Leukaemia -- a developmental perspective (English)

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10 August 2017

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Shai Izraeli

1

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10 August 2017

language of work or name

English

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publication date

1 July 2004

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British Journal of Haematology

10 August 2017

published in

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10 August 2017

volume

126

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10 August 2017

issue

1

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10 August 2017

page(s)

3-10

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An scl gene product lacking the transactivation domain induces bony abnormalities and cooperates with LMO1 to generate T-cell malignancies in transgenic mice

10 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

E2A deficiency leads to abnormalities in alphabeta T-cell development and to rapid development of T-cell lymphomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Chromosome 21 abnormalities with AML1 amplification in acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

The Runx genes as dominant oncogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Transcriptional regulation of erythropoiesis: an affair involving multiple partners

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

GATA-factor dependence of the multitype zinc-finger protein FOG-1 for its essential role in megakaryopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Disordered T-cell development and T-cell malignancies in SCL LMO1 double-transgenic mice: parallels with E2A-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

The AML1-ETO chimaeric transcription factor in acute myeloid leukaemia: biology and clinical significance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

RUNX1 and GATA-1 coexpression and cooperation in megakaryocytic differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Early thymocyte development is regulated by modulation of E2A protein activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Gene expression signatures define novel oncogenic pathways in T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Fetal origins of the TEL-AML1 fusion gene in identical twins with leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Lmo2 and Scl/Tal1 convert non-axial mesoderm into haemangioblasts which differentiate into endothelial cells in the absence of Gata1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

The detection and significance of chromosomal abnormalities in childhood acute lymphoblastic leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Pattern of malignant disorders in individuals with Down's syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

IL-7Ralpha and E47: independent pathways required for development of multipotent lymphoid progenitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Runx1 is essential for hematopoietic commitment at the hemangioblast stage of development in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

SCL assembles a multifactorial complex that determines glycophorin A expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

AML1, AML2, and AML3, the human members of the runt domain gene-family: cDNA structure, expression, and chromosomal localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

The LMO2 T-cell oncogene is activated via chromosomal translocations or retroviral insertion during gene therapy but has no mandatory role in normal T-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

X-linked thrombocytopenia caused by a novel mutation of GATA-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Haematopoietic stem cells retain long-term repopulating activity and multipotency in the absence of stem-cell leukaemia SCL/tal-1 gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Chromosome translocations and covert leukemic clones are generated during normal fetal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Familial dyserythropoietic anaemia and thrombocytopenia due to an inherited mutation in GATA1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Analysis of TEL proteins in human leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

The role of TEL fusion genes in pediatric leukemias

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Absence of blood formation in mice lacking the T-cell leukaemia oncoprotein tal-1/SCL

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

A lineage-selective knockout establishes the critical role of transcription factor GATA-1 in megakaryocyte growth and platelet development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Core-binding factors in haematopoiesis and leukaemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Association of CBFA2 mutation with decreased platelet PKC-θ and impaired receptor-mediated activation of GPIIb-IIIa and pleckstrin phosphorylation: proteins regulated by CBFA2 play a role in GPIIb-IIIa activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Regulation of pT alpha gene expression by a dosage of E2A, HEB, and SCL

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

The LIM-domain binding protein Ldb1 and its partner LMO2 act as negative regulators of erythroid differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

The LIM-only protein Lmo2 is a bridging molecule assembling an erythroid, DNA-binding complex which includes the TAL1, E47, GATA-1 and Ldb1/NLI proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Disruption of the Cbfa2 gene causes necrosis and hemorrhaging in the central nervous system and blocks definitive hematopoiesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

The CBFbeta subunit is essential for CBFalpha2 (AML1) function in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Acquired mutations in GATA1 in the megakaryoblastic leukemia of Down syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Identification of a TAL1 Target Gene Reveals a Positive Role for the LIM Domain-Binding Protein Ldb1 in Erythroid Gene Expression and Differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

The T cell leukemia LIM protein Lmo2 is necessary for adult mouse hematopoiesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

High incidence of T-cell tumors in E2A-null mice and E2A/Id1 double-knockout mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Targeted deletion of a high-affinity GATA-binding site in the GATA-1 promoter leads to selective loss of the eosinophil lineage in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

X-linked thrombocytopenia with thalassemia from a mutation in the amino finger of GATA-1 affecting DNA binding rather than FOG-1 interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

Amplification of AML1 in acute lymphoblastic leukemia is associated with a poor outcome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2141.2004.04986.X

10.1111/J.1365-2141.2004.04986.X

21 January 2018

Identifiers

DOI

1 reference

10 August 2017

1 reference