(Q35808047)

English

Alum Adjuvant Enhances Protection against Respiratory Syncytial Virus but Exacerbates Pulmonary Inflammation by Modulating Multiple Innate and Adaptive Immune Cells

scientific article published on 15 October 2015

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

Alum Adjuvant Enhances Protection against Respiratory Syncytial Virus but Exacerbates Pulmonary Inflammation by Modulating Multiple Innate and Adaptive Immune Cells (English)

1 reference

Europe PubMed Central

10 August 2017

author name string

Ki-Hye Kim

1

1 reference

Europe PubMed Central

10 August 2017

Young-Tae Lee

2

1 reference

Europe PubMed Central

10 August 2017

Hye Suk Hwang

3

1 reference

Europe PubMed Central

10 August 2017

Young-Man Kwon

4

1 reference

Europe PubMed Central

10 August 2017

Yu-Jin Jung

5

1 reference

Europe PubMed Central

10 August 2017

Youri Lee

6

1 reference

Europe PubMed Central

10 August 2017

Jong Seok Lee

7

1 reference

Europe PubMed Central

10 August 2017

Yu-Na Lee

8

1 reference

Europe PubMed Central

10 August 2017

Soojin Park

9

1 reference

Europe PubMed Central

10 August 2017

Sang-Moo Kang

10

1 reference

Europe PubMed Central

10 August 2017

language of work or name

0 references

publication date

15 October 2015

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

10

1 reference

Europe PubMed Central

10 August 2017

10

1 reference

Europe PubMed Central

10 August 2017

e0139916

1 reference

Europe PubMed Central

10 August 2017

copyright license

Creative Commons Attribution 4.0 International

15 October 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

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1 reference

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Maternal antibodies by passive immunization with formalin inactivated respiratory syncytial virus confer protection without vaccine-enhanced disease

1 reference

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1 reference

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Mechanisms of action of adjuvants

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The role of dendritic cells in innate and adaptive immunity to respiratory syncytial virus, and implications for vaccine development.

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An adjuvanted respiratory syncytial virus fusion protein induces protection in aged BALB/c mice

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Immunogenicity and protective capacity of a virosomal respiratory syncytial virus vaccine adjuvanted with monophosphoryl lipid A in mice

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Differential pathogenesis of respiratory syncytial virus clinical isolates in BALB/c mice

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Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis

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Plasmacytoid dendritic cells enhance mortality during lethal influenza infections by eliminating virus-specific CD8 T cells

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Newcastle disease virus-like particles containing respiratory syncytial virus G protein induced protection in BALB/c mice, with no evidence of immunopathology

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Pulmonary eosinophilia is attenuated by early responding CD8(+) memory T cells in a murine model of RSV vaccine-enhanced disease

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Respiratory syncytial virus-induced activation and migration of respiratory dendritic cells and subsequent antigen presentation in the lung-draining lymph node

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Comparison of histochemical methods for murine eosinophil detection in an RSV vaccine-enhanced inflammation model.

1 reference

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Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease

1 reference

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Pulmonary eosinophilia requires interleukin-5, eotaxin-1, and CD4+ T cells in mice immunized with respiratory syncytial virus G glycoprotein

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The balance between plasmacytoid DC versus conventional DC determines pulmonary immunity to virus infections

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Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling

1 reference

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Respiratory syncytial virus infection in elderly and high-risk adults

1 reference

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Mobilization of plasmacytoid and myeloid dendritic cells to mucosal sites in children with respiratory syncytial virus and other viral respiratory infections

1 reference

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Promotion of B cell immune responses via an alum-induced myeloid cell population

1 reference

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IL-13 is sufficient for respiratory syncytial virus G glycoprotein-induced eosinophilia after respiratory syncytial virus challenge

1 reference

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Gamma interferon-dependent protection of the mouse upper respiratory tract following parenteral immunization with a respiratory syncytial virus G protein fragment

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A role for immune complexes in enhanced respiratory syncytial virus disease

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A push-pull approach to maximize vaccine efficacy: abrogating suppression with an IL-13 inhibitor while augmenting help with granulocyte/macrophage colony-stimulating factor and CD40L

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Adjuvants of immunity: harnessing innate immunity to promote adaptive immunity

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Virus-specific CTL responses induced by an H-2K(d)-restricted, motif-negative 15-mer peptide from the fusion protein of respiratory syncytial virus

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Expression of mouse interleukin-4 by a recombinant ectromelia virus suppresses cytolytic lymphocyte responses and overcomes genetic resistance to mousepox.

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The attachment (G) glycoprotein of respiratory syncytial virus contains a single immunodominant epitope that elicits both Th1 and Th2 CD4+ T cell responses.

1 reference

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T-cell priming by type-1 and type-2 polarized dendritic cells: the concept of a third signal

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Priming with live respiratory syncytial virus (RSV) prevents the enhanced pulmonary inflammatory response seen after RSV challenge in BALB/c mice immunized with formalin-inactivated RSV.

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Inflammatory cytokines enhance the in vivo clonal expansion and differentiation of antigen-activated CD4+ T cells.

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Priming immunization determines T helper cytokine mRNA expression patterns in lungs of mice challenged with respiratory syncytial virus

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Enhanced pulmonary histopathology induced by respiratory syncytial virus (RSV) challenge of formalin-inactivated RSV-immunized BALB/c mice is abrogated by depletion of interleukin-4 (IL-4) and IL-10.

1 reference

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1 reference

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Role of T lymphocyte subsets in the pathogenesis of primary infection and rechallenge with respiratory syncytial virus in mice

1 reference

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1 reference

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IL-13 is required for eosinophil entry into the lung during respiratory syncytial virus vaccine-enhanced disease.

1 reference

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Respiratory syncytial virus differentially activates murine myeloid and plasmacytoid dendritic cells

1 reference

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Respiratory syncytial virus replication is prolonged by a concomitant allergic response

1 reference

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Protective and disease-enhancing immune responses induced by recombinant modified vaccinia Ankara (MVA) expressing respiratory syncytial virus proteins.

1 reference

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1 reference

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Pulmonary T cells induced by respiratory syncytial virus are functional and can make an important contribution to long-lived protective immunity

1 reference

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Vaccine-enhanced respiratory syncytial virus disease in cotton rats following immunization with Lot 100 or a newly prepared reference vaccine

1 reference

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Th2 polarization by Der p 1--pulsed monocyte-derived dendritic cells is due to the allergic status of the donors

1 reference

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Mucosal delivery of a respiratory syncytial virus CTL peptide with enterotoxin-based adjuvants elicits protective, immunopathogenic, and immunoregulatory antiviral CD8+ T cell responses

1 reference

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Murine cytotoxic T cells specific to respiratory syncytial virus recognize different antigenic subtypes of the virus.

1 reference

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Aluminium hydroxide adjuvant initiates strong antigen-specific Th2 responses in the absence of IL-4- or IL-13-mediated signaling

1 reference

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IL-4 diminishes perforin-mediated and increases Fas ligand-mediated cytotoxicity In vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/26468884

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: alum adjuvant stimulates inflammatory dendritic cells through activation of the NALP3 inflammasome

1 reference

https://pubmed.ncbi.nlm.nih.gov/26468884

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD4 and CD8 expression by dendritic cell subtypes in mouse thymus and spleen

1 reference

https://pubmed.ncbi.nlm.nih.gov/26468884

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reciprocal control of T helper cell and dendritic cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/26468884

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-6 Production by Pulmonary Dendritic Cells Impedes Th1 Immune Responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/26468884

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0139916

1 reference

Europe PubMed Central

10 August 2017

2015PLoSO..1039916K

0 references

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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