(Q35811338)

10 August 2017

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title

Injury research in the genomic era. (English)

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10 August 2017

J Perren Cobb

1

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10 August 2017

Grant E O'Keefe

series ordinal

2

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10 August 2017

language of work or name

English

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publication date

1 June 2004

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10 August 2017

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10 August 2017

volume

363

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10 August 2017

issue

9426

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10 August 2017

page(s)

2076-2083

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The complications of trauma and their associated costs in a level I trauma center

10 August 2017

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The risk factors and time course of sepsis and organ dysfunction after burn trauma

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Postinjury multiple organ failure: a bimodal phenomenon

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Multiple organ dysfunction syndrome: exploring the paradigm of complex nonlinear systems

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7 January 2021

Functional genomics: it's all how you read it

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Inflammatory cytokines and cell response in surgery

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7 January 2021

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7 January 2021

The cardiovascular response of normal humans to the administration of endotoxin.

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Experimental human endotoxemia increases cardiac regularity: results from a prospective, randomized, crossover trial

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Comparison of the mortality and inflammatory response of two models of sepsis: lipopolysaccharide vs. cecal ligation and puncture

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7 January 2021

Early detection of increased tumour necrosis factor alpha (TNFalpha) and soluble TNF receptor protein plasma levels after trauma reveals associations with the clinical course

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7 January 2021

Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells

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7 January 2021

Inflammatory cytokines in major surgery: a functional perspective

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Differential effects of IL-6 on systemic and central production of TNF: a study with IL-6-deficient mice

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7 January 2021

IL-6 is an antiinflammatory cytokine required for controlling local or systemic acute inflammatory responses

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7 January 2021

Development of chronic inflammatory arthropathy resembling rheumatoid arthritis in interleukin 1 receptor antagonist-deficient mice

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7 January 2021

Sir Isaac Newton, sepsis, SIRS, and CARS

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7 January 2021

The pathophysiology and treatment of sepsis

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7 January 2021

Normal responses to injury prevent systemic inflammation and can be immunosuppressive

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7 January 2021

The Catecholamine Response to Multisystem Trauma

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7 January 2021

Increased plasma free cyclic-AMP levels following major trauma and their relevance to the immune response

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7 January 2021

Epinephrine inhibits tumor necrosis factor-alpha and potentiates interleukin 10 production during human endotoxemia

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7 January 2021

Painful stimulation suppresses joint inflammation by inducing shedding of L-selectin from neutrophils.

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7 January 2021

L-selectin expression affects T-cell circulation following isoproterenol infusion in humans

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7 January 2021

Regulation of L-selectin and CD18 on bovine neutrophils by glucocorticoids: effects of cortisol and dexamethasone

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7 January 2021

The alveolar space is the site of intense inflammatory and profibrotic reactions in the early phase of acute respiratory distress syndrome

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7 January 2021

Anti-inflammatory therapies to treat sepsis and septic shock: a reassessment

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7 January 2021

Sepsis research: we must change course

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7 January 2021

Safeguarding patients in clinical trials with high mortality rates

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7 January 2021

Evaluating surrogate endpoints

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7 January 2021

Efficacy and safety of recombinant human activated protein C for severe sepsis

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7 January 2021

The community of the self

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7 January 2021

Integrated genomic and proteomic analyses of a systematically perturbed metabolic network

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7 January 2021

Inferring genetic networks and identifying compound mode of action via expression profiling

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7 January 2021

Hierarchical organization of modularity in metabolic networks

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7 January 2021

The neuroendocrine response to stress is a dynamic process.

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7 January 2021

The inflammatory reflex

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7 January 2021

Interleukin-6 gene polymorphism and insulin sensitivity.

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7 January 2021

Association of TNF2, a TNF-alpha promoter polymorphism, with septic shock susceptibility and mortality: a multicenter study

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7 January 2021

TLR4 mutations are associated with endotoxin hyporesponsiveness in humans

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7 January 2021

Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation

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7 January 2021

Relation of a TNF gene polymorphism to severe sepsis in trauma patients

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7 January 2021

Angiotensin converting enzyme insertion/deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome.

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7 January 2021

Plasminogen-activator-inhibitor-1 4G/5G promoter polymorphism and prognosis of severely injured patients

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7 January 2021

Interferon-gamma gene polymorphisms and the development of sepsis in patients with trauma

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7 January 2021

Genetic and environmental influences on premature death in adult adoptees

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7 January 2021

Genomic polymorphisms in sepsis

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7 January 2021

Variation in the tumor necrosis factor-alpha gene promoter region may be associated with death from meningococcal disease

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7 January 2021

Septic shock and respiratory failure in community-acquired pneumonia have different TNF polymorphism associations

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7 January 2021

A polymorphism that affects OCT-1 binding to the TNF promoter region is associated with severe malaria

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7 January 2021

A comprehensive review of genetic association studies

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7 January 2021

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

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7 January 2021

Cooperative influence of genetic polymorphisms on interleukin 6 transcriptional regulation

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7 January 2021

The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis

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7 January 2021

Interleukin 10 secretion in relation to human IL-10 locus haplotypes

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7 January 2021

Biomedical discovery with DNA arrays

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7 January 2021

Microarrays--the 21st century divining rod?

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7 January 2021

Transcriptional regulatory networks in Saccharomyces cerevisiae

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7 January 2021

Transcription. Of chips and ChIPs

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7 January 2021

Dissecting the regulatory circuitry of a eukaryotic genome

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7 January 2021

Global analysis of the genetic network controlling a bacterial cell cycle

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7 January 2021

A gene expression map for Caenorhabditis elegans.

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7 January 2021

Human genome studies expected to revolutionize cancer classification

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7 January 2021

Medicine. DNA arrays reveal cancer in its many forms

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7 January 2021

Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

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7 January 2021

Gene-expression profiles predict survival of patients with lung adenocarcinoma

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7 January 2021

Gene-Expression Profiles in Hereditary Breast Cancer

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7 January 2021

Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays

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7 January 2021

Molecular portraits of human breast tumours

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7 January 2021

Gene expression profiling predicts clinical outcome of breast cancer

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7 January 2021

A gene-expression signature as a predictor of survival in breast cancer

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7 January 2021

Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning

1 reference

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7 January 2021

Gene chips inch toward the clinic

1 reference

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7 January 2021

The polycomb group protein EZH2 is involved in progression of prostate cancer

1 reference

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7 January 2021

Proteomics. Searching for recipes for protein chips

1 reference

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7 January 2021

Global analysis of protein activities using proteome chips

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7 January 2021

Cutting-edge technology. II. Proteomics: core technologies and applications in physiology

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7 January 2021

Spot the differences: proteomics in cancer research

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7 January 2021

A genomic and proteomic analysis of activation of the human neutrophil by lipopolysaccharide and its mediation by p38 mitogen-activated protein kinase.

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2916460-X

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7 January 2021

Lethality and centrality in protein networks

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7 January 2021

Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction

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7 January 2021

Uncoupling of biological oscillators: a complementary hypothesis concerning the pathogenesis of multiple organ dysfunction syndrome

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7 January 2021

Death and disability from injury: a global challenge

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2916460-X

7 January 2021

Implications of the Human Genome Project for medical science.

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https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2916460-X

7 January 2021

Cytokines, chaos, and complexity.

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https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2916460-X

7 January 2021

Physicians apply genome research to treating critical illness and injury

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7 January 2021

Complexity, chaos, and incomprehensibility: parsing the biology of critical illness.

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7 January 2021

Injury in the era of genomics

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7 January 2021

Functional genomics of critical illness and injury

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https://api.crossref.org/works/10.1016%2FS0140-6736%2804%2916460-X

7 January 2021

Functional genomic hypothesis generation and experimentation by a robot scientist

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7 January 2021

Medicine. The NIH Roadmap

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7 January 2021

10.1016/S0140-6736(04)16460-X

Identifiers

DOI

1 reference

10 August 2017

1 reference