(Q35827121)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

title

Bosentan decreases the plasma concentration of sildenafil when coprescribed in pulmonary hypertension (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

main subject

pulmonary hypertension

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

author name string

Gideon A Paul

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

J Simon R Gibbs

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Allifia Abbas

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Martin R Wilkins

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

language of work or name

English

0 references

publication date

1 July 2005

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

British Journal of Clinical Pharmacology

13 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

volume

60

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

page(s)

107-112

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

Clinical pharmacology of bosentan, a dual endothelin receptor antagonist

13 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884910

The effects of steady-state erythromycin and azithromycin on the pharmacokinetics of sildenafil in healthy volunteers.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884910

Comparative human pharmacokinetics and metabolism of single-dose oral and intravenous sildenafil

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884910

Pharmacokinetics of sildenafil after single oral doses in healthy male subjects: absolute bioavailability, food effects and dose proportionality

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884910

Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884910

In vitro biotransformation of sildenafil (Viagra): identification of human cytochromes and potential drug interactions

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884910

Inhibitory effects of amiodarone and its N-deethylated metabolite on human cytochrome P450 activities: prediction of in vivo drug interactions

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884910

Cyclic GMP phosphodiesterase-5: target of sildenafil

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884910

Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebo-controlled study

11 July 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02383.X

Phosphodiesterase type 5 as a target for the treatment of hypoxia-induced pulmonary hypertension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02383.X

Chronic sildenafil treatment inhibits monocrotaline-induced pulmonary hypertension in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02383.X

Clinical and haemodynamic effects of sildenafil in pulmonary hypertension: acute and mid-term effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02383.X

Simultaneous assay of sildenafil and desmethylsildenafil in human plasma using liquid chromatography-tandem mass spectrometry on silica column with aqueous-organic mobile phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02383.X

Diltiazem-mediated inhibition of sildenafil metabolism may promote nitrate-induced hypotension

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-2125.2005.02383.X

A study of clinical efficacy of sildenafil in patients with primary pulmonary hypertension.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1884910

Bosentan therapy for pulmonary arterial hypertension

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15963102

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Primary pulmonary hypertension

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15963102

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Pharmacokinetics and metabolism of sildenafil in mouse, rat, rabbit, dog and man

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/15963102

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1111/J.1365-2125.2005.02383.X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15963102%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

PubMed publication ID

15963102

1 reference