(Q35829128)

10 August 2017

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title

Application of drug delivery technologies in lead candidate selection and optimization (English)

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10 August 2017

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Mahesh V Chaubal

1

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10 August 2017

publication date

1 July 2004

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10 August 2017

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10 August 2017

volume

9

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10 August 2017

issue

14

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10 August 2017

page(s)

603-609

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The price of innovation: new estimates of drug development costs

10 August 2017

cites work

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7 January 2021

Lead optimization in 12 months? True confessions of a chemistry team

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7 January 2021

Combinatorial compound libraries for drug discovery: an ongoing challenge

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7 January 2021

Drug discovery by dynamic combinatorial libraries

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7 January 2021

Integration of virtual and high-throughput screening

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7 January 2021

Role of the development scientist in compound lead selection and optimization

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7 January 2021

Biopharmaceutics classification system: the scientific basis for biowaiver extensions

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7 January 2021

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

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7 January 2021

An integrated process for measuring the physicochemical properties of drug candidates in a preclinical discovery environment

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7 January 2021

Prediction of aqueous solubility of a diverse set of compounds using quantitative structure-property relationships

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7 January 2021

Prediction of aqueous solubility of organic compounds using a quantitative structure-property relationship.

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7 January 2021

Prediction of intestinal absorption: comparative assessment of GASTROPLUS and IDEA.

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7 January 2021

An automated approach to salt selection for new unique trazodone salts

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7 January 2021

Assessment of oral bioavailability enhancing approaches for SB-247083 using flow-through cell dissolution testing as one of the screens

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7 January 2021

An intravenous formulation decision tree for discovery compound formulation development

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7 January 2021

Solid Dispersions: Revival with Greater Possibilities and Applications in Oral Drug Delivery

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7 January 2021

Antimicrobial activity of β-lactam antibiotics against clinical pathogens after molecular inclusion in several cyclodextrins. A novel approach to bacterial resistance

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7 January 2021

Potential Use of Cyclodextrins to Enhance the Solubility of YM466 in Aqueous Solution

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7 January 2021

Safety assessment of selected cyclodextrins - effect on ciliary activity using a human cell suspension culture model exhibiting in vitro ciliogenesis

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7 January 2021

When can cyclodextrins be considered for solubilization purposes?

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7 January 2021

Pharmacological effects of formulation vehicles : implications for cancer chemotherapy

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7 January 2021

Effect of signal interference from dosing excipients on pharmacokinetic screening of drug candidates by liquid chromatography/mass spectrometry

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7 January 2021

Synthesis and Evaluation of PEG414, a Novel Formulating Agent that Avoids Analytical Problems Associated with Polydisperse Vehicles such as PEG400

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7 January 2021

Lipid drug delivery and rational formulation design for lipophilic drugs with low oral bioavailability, applied to cyclosporine

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7 January 2021

In vitro assessment of oral lipid based formulations

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7 January 2021

Stealth liposomes and long circulating nanoparticles: critical issues in pharmacokinetics, opsonization and protein-binding properties

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7 January 2021

Brain uptake of thiamine-coated nanoparticles

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7 January 2021

Nanosizing: a formulation approach for poorly-water-soluble compounds

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7 January 2021

Formulation and antitumor activity evaluation of nanocrystalline suspensions of poorly soluble anticancer drugs

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7 January 2021

Nanoparticle drug delivery system for intravenous delivery of topoisomerase inhibitors

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7 January 2021

An in-vitro assessment of a NanoCrystal beclomethasone dipropionate colloidal dispersion via ultrasonic nebulization

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7 January 2021

Ultra-long-duration local anesthesia produced by injection of lecithin-coated tetracaine microcrystals.

1 reference

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7 January 2021

A high-throughput combinatorial approach for the discovery of a cremophor EL-free paclitaxel formulation

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7 January 2021

10.1016/S1359-6446(04)03171-X

Identifiers

DOI

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10 August 2017

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