(Q35829420)

English

NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease

scientific article published in September 2000

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

NOS-2 mediates the protective anti-inflammatory and antifibrotic effects of the Th1-inducing adjuvant, IL-12, in a Th2 model of granulomatous disease (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

author name string

M Hesse

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

A W Cheever

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

D Jankovic

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

T A Wynn

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

1 September 2000

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

The American Journal of Pathology

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

157

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

945-955

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

T helper 1 cells and interferon gamma regulate allergic airway inflammation and mucus production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Cooperation between Th1 and Th2 cells in a murine model of eosinophilic airway inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

An IL-13 inhibitor blocks the development of hepatic fibrosis during a T-helper type 2-dominated inflammatory response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

The role of nitric oxide in the pathogenesis of multiple sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

The role of nitric oxide in sepsis--an overview

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Other functions, other genes: alternative activation of antigen-presenting cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Nitric oxide as a bifunctional regulator of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

The initiation and function of Th2 responses during infection with Schistosoma mansoni.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Collagen deposition in a non-fibrotic lung granuloma model after nitric oxide inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Immune suppression by recombinant interleukin (rIL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

A dichotomous role for nitric oxide during acute Toxoplasma gondii infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Of microbes, macrophages and nitric oxide.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Nitric oxide and macrophage function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

The role of interleukin 12 and nitric oxide in the development of spontaneous autoimmune disease in MRL/MP-lpr/lpr mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Suppression of arthritis by an inhibitor of nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Altered immune responses in mice lacking inducible nitric oxide synthase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

The role of nitric oxide in the pathogenesis of spontaneous murine autoimmune disease: increased nitric oxide production and nitric oxide synthase expression in MRL-lpr/lpr mice, and reduction of spontaneous glomerulonephritis and arthritis by orall

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Cytokine regulation of granuloma formation in schistosomiasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Induction of nitrite/nitrate synthesis in murine macrophages by BCG infection, lymphokines, or interferon-gamma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Antiproliferative effect of IFN-gamma in immune regulation. III. Differential selection of TH1 and TH2 murine helper T lymphocyte clones using recombinant IL-2 and recombinant IFN-gamma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

11 July 2018

Studies with double cytokine-deficient mice reveal that highly polarized Th1- and Th2-type cytokine and antibody responses contribute equally to vaccine-induced immunity to Schistosoma mansoni

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

24 September 2018

Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: competitive regulation by CD4+ T cells correlates with Th1/Th2 phenotype.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

24 September 2018

Contractile depression and expression of proinflammatory cytokines and iNOS in viral myocarditis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

24 September 2018

Nitric oxide and the Th2 response combine to prevent severe hepatic damage during Schistosoma mansoni infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885696

15 November 2018

The inflammatory nature of allergic disease

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964607-X

7 January 2021

An IL-12-based vaccination method for preventing fibrosis induced by schistosome infection

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964607-X

7 January 2021

Inducible nitric oxide synthase plays a critical role in resolving intestinal inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964607-X

7 January 2021

IL-13 is a key regulatory cytokine for Th2 cell-mediated pulmonary granuloma formation and IgE responses induced by Schistosoma mansoni eggs

1 reference

https://pubmed.ncbi.nlm.nih.gov/10980133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of cytokine mRNA expression during primary granuloma formation induced by eggs of Schistosoma mansoni

1 reference

https://pubmed.ncbi.nlm.nih.gov/10980133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-alpha and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/10980133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anti-IL-4 treatment of Schistosoma mansoni-infected mice inhibits development of T cells and non-B, non-T cells expressing Th2 cytokines while decreasing egg-induced hepatic fibrosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10980133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High levels of TH2 cytokine gene expression in systemic lupus erythematosus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10980133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IL-4 protects against TNF-alpha-mediated cachexia and death during acute schistosomiasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/10980133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Th2 cells are required for the Schistosoma mansoni egg-induced granulomatous response.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10980133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of airway inflammation by CpG oligodeoxynucleotides in a murine model of asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/10980133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antisense knockdown of inducible nitric oxide synthase inhibits induction of experimental autoimmune encephalomyelitis in SJL/J mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10980133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of the cytokine phenotype in an experimental lung granuloma model by inhibiting nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/10980133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-gamma, IL-12, and TNF-alpha are required to maintain reduced liver pathology in mice vaccinated with Schistosoma mansoni eggs and IL-12

1 reference

https://pubmed.ncbi.nlm.nih.gov/10980133

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/S0002-9440(10)64607-X

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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