(Q35829510)

English

Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy

scientific article published in November 2000

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy (English)

1 reference

Europe PubMed Central

10 August 2017

author name string

D Cosgrove

1

1 reference

Europe PubMed Central

10 August 2017

K Rodgers

2

1 reference

Europe PubMed Central

10 August 2017

D Meehan

3

1 reference

Europe PubMed Central

10 August 2017

C Miller

4

1 reference

Europe PubMed Central

10 August 2017

K Bovard

5

1 reference

Europe PubMed Central

10 August 2017

A Gilroy

6

1 reference

Europe PubMed Central

10 August 2017

H Gardner

7

1 reference

Europe PubMed Central

10 August 2017

V Kotelianski

8

1 reference

Europe PubMed Central

10 August 2017

P Gotwals

9

1 reference

Europe PubMed Central

10 August 2017

A Amatucci

10

1 reference

Europe PubMed Central

10 August 2017

R Kalluri

11

1 reference

Europe PubMed Central

10 August 2017

language of work or name

0 references

publication date

1 November 2000

1 reference

Europe PubMed Central

10 August 2017

The American Journal of Pathology

1 reference

Europe PubMed Central

10 August 2017

157

1 reference

Europe PubMed Central

10 August 2017

5

1 reference

Europe PubMed Central

10 August 2017

1649-1659

1 reference

Europe PubMed Central

10 August 2017

Renal basement membrane components

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Role for transforming growth factor-beta1 in alport renal disease progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Insertional mutation of the collagen genes Col4a3 and Col4a4 in a mouse model of Alport syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Enhancement of cell adhesion and spreading by a cartilage-specific noncollagenous protein, cartilage matrix protein (CMP/Matrilin-1), via integrin alpha1beta1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Recombinant soluble human alpha 3 beta 1 integrin: purification, processing, regulation, and specific binding to laminin-5 and invasin in a mutually exclusive manner

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

The N-terminal globular domain of the laminin alpha1 chain binds to alpha1beta1 and alpha2beta1 integrins and to the heparan sulfate-containing domains of perlecan

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

Integrin alpha1beta1 mediates a unique collagen-dependent proliferation pathway in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Isoform switching of type IV collagen is developmentally arrested in X-linked Alport syndrome leading to increased susceptibility of renal basement membranes to endoproteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Alport's syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Alterations in the expression of the alpha 3 beta 1 integrin in certain membrane domains of the glomerular epithelial cells (podocytes) in diabetes mellitus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Molecular and functional defects in kidneys of mice lacking collagen alpha 3(IV): implications for Alport syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Merosin and laminin in myogenesis; specific requirement for merosin in myotube stability and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Alport syndrome--clinical phenotypes, incidence, and pathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Deletion of integrin alpha 1 by homologous recombination permits normal murine development but gives rise to a specific deficit in cell adhesion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Identification of mutations in the alpha 3(IV) and alpha 4(IV) collagen genes in autosomal recessive Alport syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Collagen IV alpha 3, alpha 4, and alpha 5 chains in rodent basal laminae: sequence, distribution, association with laminins, and developmental switches

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Mouse kalinin B1 (laminin beta 3 chain): cloning and tissue distribution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Role of the α1β1 integrin complex in collagen gel contraction in vitro by fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Characterization of recombinant soluble human transforming growth factor-β receptor Type II (rhTGF-βsRII)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Selective immunoreactivities of kidney basement membranes to monoclonal antibodies against laminin: localization of the end of the long arm and the short arms to discrete microdomains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Identification of mutations in the COL4A5 collagen gene in Alport syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Molecular heterogeneity of basal laminae: isoforms of laminin and collagen IV at the neuromuscular junction and elsewhere

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Ontogenesis of glomerular basement membrane: structural and functional properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Kalinin: an epithelium-specific basement membrane adhesion molecule that is a component of anchoring filaments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Transforming growth factor-beta in disease: the dark side of tissue repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

The dermal-epidermal junction of human skin contains a novel laminin variant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

27 July 2018

Gene therapy by transforming growth factor-beta receptor-IgG Fc chimera suppressed extracellular matrix accumulation in experimental glomerulonephritis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

24 September 2018

Glomerular extracellular matrix components and integrins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

24 September 2018

Ultrastructural and immunohistochemical findings in Alport's syndrome: a study of 108 patients from 97 Italian families with particular emphasis on COL4A5 gene mutation correlations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

24 September 2018

Regulation of podocyte structure during the development of nephrotic syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

24 September 2018

Mutations in the type IV collagen alpha 3 (COL4A3) gene in autosomal recessive Alport syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1885718

24 September 2018

Distribution of the alpha 1 and alpha 2 chains of collagen IV and of collagens V and VI in Alport syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

Autosomal recessive Alport syndrome: Immunohistochemical study of type IV collagen chain distribution

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

Glomerular basement membrane. Identification of a novel disulfide-cross-linked network of alpha3, alpha4, and alpha5 chains of type IV collagen and its implications for the pathogenesis of Alport syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

Collagen COL4A3 knockout: a mouse model for autosomal Alport syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

Analysis of the interaction between two TGF-beta-binding proteins and three TGF-beta isoforms using surface plasmon resonance

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

Soluble transforming growth factor-beta type II receptor inhibits negative remodeling, fibroblast transdifferentiation, and intimal lesion formation but not endothelial growth

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

Mesangial cells and their adhesive properties

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

The structural relationship between mesangial cells and basement membrane of the renal glomerulus

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

Mesangial cell-glomerular basement membrane connections counteract glomerular capillary and mesangium expansion

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

Transforming growth factor-beta (TGF-beta) stimulates the expression of beta1 integrins and adhesion by rat mesangial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

The laminin alpha2-chain short arm mediates cell adhesion through both the alpha1beta1 and alpha2beta1 integrins

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

Sustained expression of TGF-beta 1 underlies development of progressive kidney fibrosis

1 reference

https://api.crossref.org/works/10.1016%2FS0002-9440%2810%2964802-X

7 January 2021

Distribution of Integrin Subunits in Normal Human Kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/11073824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Administration of AGEs in vivo induces genes implicated in diabetic glomerulosclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11073824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of matrix glycation on expression of type IV collagen, MMP-2, MMP-9 and TIMP-1 by human mesangial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11073824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha 3 beta 1 integrin has a crucial role in kidney and lung organogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11073824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal expression of fibrotic matrix proteins and of transforming growth factor-beta (TGF-beta) isoforms in TGF-beta transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11073824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alpha1beta1 integrin-mediated collagen matrix remodeling by rat mesangial cells is differentially regulated by transforming growth factor-beta and platelet-derived growth factor-BB

1 reference

https://pubmed.ncbi.nlm.nih.gov/11073824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for separate networks of classical and novel basement membrane collagen. Characterization of alpha 3(IV)-alport antigen heterodimer

1 reference

https://pubmed.ncbi.nlm.nih.gov/11073824

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/S0002-9440(10)64802-X

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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