(Q35838756)

English

Notch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: implications for cellular Aβ metabolism

scientific article published on 19 October 2011

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

Notch signaling proteins HES-1 and Hey-1 bind to insulin degrading enzyme (IDE) proximal promoter and repress its transcription and activity: implications for cellular Aβ metabolism (English)

1 reference

Europe PubMed Central

10 August 2017

author name string

María C Leal

1

1 reference

Europe PubMed Central

10 August 2017

Ezequiel I Surace

2

1 reference

Europe PubMed Central

10 August 2017

María P Holgado

3

1 reference

Europe PubMed Central

10 August 2017

Carina C Ferrari

4

1 reference

Europe PubMed Central

10 August 2017

Rodolfo Tarelli

5

1 reference

Europe PubMed Central

10 August 2017

Fernando Pitossi

6

1 reference

Europe PubMed Central

10 August 2017

Thomas Wisniewski

7

1 reference

Europe PubMed Central

10 August 2017

Eduardo M Castaño

8

1 reference

Europe PubMed Central

10 August 2017

Laura Morelli

9

1 reference

Europe PubMed Central

10 August 2017

language of work or name

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publication date

19 October 2011

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Europe PubMed Central

10 August 2017

Biochimica et Biophysica Acta

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Europe PubMed Central

10 August 2017

1823

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Europe PubMed Central

10 August 2017

2

1 reference

Europe PubMed Central

10 August 2017

227-235

1 reference

Europe PubMed Central

10 August 2017

describes a project that uses

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3307219/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

The noradrenaline precursor L-DOPS reduces pathology in a mouse model of Alzheimer's disease

1 reference

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Glucocorticoids facilitate astrocytic amyloid-β peptide deposition by increasing the expression of APP and BACE1 and decreasing the expression of amyloid-β-degrading proteases

1 reference

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Expression and functional profiling of neprilysin, insulin-degrading enzyme, and endothelin-converting enzyme in prospectively studied elderly and Alzheimer's brain

1 reference

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11 July 2018

Presenilin 1 mutants impair the self-renewal and differentiation of adult murine subventricular zone-neuronal progenitors via cell-autonomous mechanisms involving notch signaling

1 reference

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11 July 2018

Cell-type dependent modulation of Notch signaling by the amyloid precursor protein

1 reference

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17β-Estradiol regulates insulin-degrading enzyme expression via an ERβ/PI3-K pathway in hippocampus: relevance to Alzheimer's prevention

1 reference

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A PPARdelta agonist reduces amyloid burden and brain inflammation in a transgenic mouse model of Alzheimer's disease

1 reference

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Neurogenesis and Alzheimer's disease: at the crossroads

1 reference

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Involvement of Notch1 signaling in neurogenesis in the subventricular zone of normal and ischemic rat brain in vivo

1 reference

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Notch signaling: the core pathway and its posttranslational regulation

1 reference

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11 July 2018

PPARgamma transcriptionally regulates the expression of insulin-degrading enzyme in primary neurons

1 reference

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11 July 2018

Detergent resistant membrane-associated IDE in brain tissue and cultured cells: Relevance to Abeta and insulin degradation

1 reference

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11 July 2018

Differential cerebral deposition of IDE and NEP in sporadic and familial Alzheimer's disease

1 reference

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11 July 2018

Abeta-degrading enzymes in Alzheimer's disease.

1 reference

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11 July 2018

Transcriptional regulation of neurogenesis: potential mechanisms in cerebral ischemia

1 reference

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Cell-autonomous notch signaling regulates endothelial cell branching and proliferation during vascular tubulogenesis.

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Twenty years of the Alzheimer's disease amyloid hypothesis: a genetic perspective

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Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients

1 reference

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11 July 2018

Reduced hippocampal insulin-degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-epsilon4 allele

1 reference

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11 July 2018

Jagged-1 mediated activation of notch signaling induces complete maturation of human keratinocytes through NF-kappaB and PPARgamma

1 reference

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11 July 2018

Insulin-degrading enzyme rapidly removes the beta-amyloid precursor protein intracellular domain (AICD)

1 reference

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11 July 2018

HERP, a new primary target of Notch regulated by ligand binding

1 reference

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11 July 2018

Immunohistochemical localization of neprilysin in the human cerebral cortex: inverse association with vulnerability to amyloid beta-protein (Abeta) deposition

1 reference

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Impact of active dendrites and structural plasticity on the memory capacity of neural tissue

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Notch signaling: cell fate control and signal integration in development

1 reference

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Additive effects of PS1 and APP mutations on secretion of the 42-residue amyloid beta-protein.

1 reference

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Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.

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Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

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Gene dosage of the amyloid beta precursor protein in Alzheimer's disease

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Transient activation of Notch signaling in the injured adult brain.

1 reference

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Gene expression profiling in the adult Down syndrome brain.

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Age-dependent decline of neprilysin in Alzheimer's disease and normal brain: inverse correlation with A beta levels.

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Regulation of steady-state beta-amyloid levels in the brain by neprilysin and endothelin-converting enzyme but not angiotensin-converting enzyme.

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Insulin degrading enzyme activity selectively decreases in the hippocampal formation of cases at high risk to develop Alzheimer's disease.

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Activation of the Notch pathway in Down syndrome: cross-talk of Notch and APP.

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Insulin-degrading enzyme in the Alzheimer's disease brain: prominent localization in neurons and senile plaques.

1 reference

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Notch is expressed in adult brain, is coexpressed with presenilin-1, and is altered in Alzheimer disease.

1 reference

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12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/22036964

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1016/J.BBAMCR.2011.09.014

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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