(Q35842159)

10 August 2017

1 reference

title

Assessing the function of genetic variants in candidate gene association studies (English)

1 reference

10 August 2017

Timothy R Rebbeck

1

1 reference

10 August 2017

Margaret Spitz

series ordinal

2

1 reference

10 August 2017

Xifeng Wu

series ordinal

3

1 reference

10 August 2017

publication date

1 August 2004

1 reference

10 August 2017

published in

Nature Reviews Genetics

1 reference

10 August 2017

volume

5

1 reference

10 August 2017

issue

8

1 reference

10 August 2017

page(s)

589-597

1 reference

Characterization of single-nucleotide polymorphisms in coding regions of human genes

10 August 2017

cites work

1 reference

SNP and haplotype variation in the human genome

21 January 2018

1 reference

DNA variability of human genes.

21 January 2018

1 reference

Single nucleotide polymorphisms and the future of genetic epidemiology

21 January 2018

1 reference

A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms

21 January 2018

1 reference

Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease

21 January 2018

1 reference

Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease

21 January 2018

1 reference

Defects in pre-mRNA processing as causes of and predisposition to diseases

21 January 2018

1 reference

Functional implications of genetic variation in non-coding DNA for disease susceptibility and gene regulation

21 January 2018

1 reference

Substrates of human hepatic cytochrome P450 3A4.

21 January 2018

1 reference

Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4.

21 January 2018

1 reference

Association of CYP3A4 genotype with treatment-related leukemia

21 January 2018

1 reference

CYP gene polymorphisms and early menarche

21 January 2018

1 reference

Genetic factors related to racial variation in plasma levels of insulin-like growth factor-1: implications for premenopausal breast cancer risk

21 January 2018

1 reference

RESPONSE: re: modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4

21 January 2018

1 reference

The CYP3A4*1B polymorphism has no functional significance and is not associated with risk of breast or ovarian cancer

21 January 2018

1 reference

Genotype???phenotype associations for common CYP3A4 and CYP3A5 variants in the basal and induced metabolism of midazolam in European- and African-American men and women

21 January 2018

1 reference

Increased transcriptional activity of the CYP3A4*1B promoter variant

21 January 2018

1 reference

Transcriptional regulation of cytochrome P4503A4 gene expression: effects of inherited mutations in the 5'-flanking region

21 January 2018

1 reference

Gene tagging in rice: a high throughput system for functional genomics

21 January 2018

1 reference

Gene trap: a way to identify novel genes and unravel their biological function

21 January 2018

1 reference

ENU mutagenesis for pharma

21 January 2018

1 reference

Protein chips: from concept to practice.

21 January 2018

1 reference

EICO (Expression-based Imprint Candidate Organizer): finding disease-related imprinted genes

21 January 2018

1 reference

In vivo characterization of regulatory polymorphisms by allele-specific quantification of RNA polymerase loading

21 January 2018

1 reference

Interrogating a high-density SNP map for signatures of natural selection

21 January 2018

1 reference

A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis

21 January 2018

1 reference

Detecting marker-disease association by testing for Hardy-Weinberg disequilibrium at a marker locus

21 January 2018

1 reference

Trimming, weighting, and grouping SNPs in human case-control association studies

21 January 2018

1 reference

SNPs, protein structure, and disease.

21 January 2018

1 reference

Predicting the functional consequences of non-synonymous single nucleotide polymorphisms: structure-based assessment of amino acid variation

21 January 2018

1 reference

Characterization of disease-associated single amino acid polymorphisms in terms of sequence and structure properties.

21 January 2018

1 reference

Evaluation of structural and evolutionary contributions to deleterious mutation prediction.

21 January 2018

1 reference

Prediction of deleterious functional effects of amino acid mutations using a library of structure-based function descriptors

21 January 2018

1 reference

Understanding human disease mutations through the use of interspecific genetic variation

21 January 2018

1 reference

A phylogenetic approach to assessing the significance of missense mutations in disease genes

21 January 2018

1 reference

A comparative study of machine-learning methods to predict the effects of single nucleotide polymorphisms on protein function.

21 January 2018

1 reference

Predicting deleterious amino acid substitutions

21 January 2018

1 reference

Accounting for human polymorphisms predicted to affect protein function

21 January 2018

1 reference

SIFT: Predicting amino acid changes that affect protein function

21 January 2018

1 reference

Human non-synonymous SNPs: server and survey

21 January 2018

1 reference

Understanding missense mutations in the BRCA1 gene: an evolutionary approach

21 January 2018

1 reference

Information theory-based analysis of CYP2C19, CYP2D6 and CYP3A5 splicing mutations.

21 January 2018

1 reference

Genomic variants in exons and introns: identifying the splicing spoilers

21 January 2018

1 reference

Towards a structural basis of human non-synonymous single nucleotide polymorphisms

21 January 2018

1 reference

Prediction of deleterious human alleles

21 January 2018

1 reference

Lessons from the CYP3A4 promoter

21 January 2018

1 reference

Ethnic differences in the frequency of prostate cancer susceptibility alleles at SRD5A2 and CYP3A4

21 January 2018

1 reference

Three-dimensional structural location and molecular functional effects of missense SNPs in the T cell receptor V? domain

21 January 2018

1 reference

An evolutionary perspective on single-nucleotide polymorphism screening in molecular cancer epidemiology

21 January 2018

1 reference

Gene structure of CYP3A4, an adult-specific form of cytochrome P450 in human livers, and its transcriptional control.

31 March 2020

1 reference

Common allelic variants of cytochrome P4503A4 and their prevalence in different populations

31 March 2020

1 reference

Interindividual differences in hepatic expression of CYP3A4: relationship to genetic polymorphism in the 5'-upstream regulatory region

31 March 2020

1 reference

Re: Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRG1403

1 reference

10 August 2017

1 reference