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Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis.
scientific article published in November 1995
Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis
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scholarly article
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Europe PubMed Central
PMC publication ID
189589
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7474089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
title
Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis
(English)
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Europe PubMed Central
PMC publication ID
189589
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7474089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
main subject
virion
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based on heuristic
inferred from title
Herpes simplex virus type 1
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author name string
L I Strelow
series ordinal
1
1 reference
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Europe PubMed Central
PMC publication ID
189589
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7474089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
D A Leib
series ordinal
2
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Europe PubMed Central
PMC publication ID
189589
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7474089%20AND%20SRC:MED&resulttype=core&format=json
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language of work or name
English
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publication date
1 November 1995
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189589
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retrieved
19 October 2019
November 1995
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published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMC publication ID
189589
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7474089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
volume
69
1 reference
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Europe PubMed Central
PMC publication ID
189589
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7474089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
issue
11
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Europe PubMed Central
PMC publication ID
189589
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7474089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
page(s)
6779-6786
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Europe PubMed Central
PMC publication ID
189589
reference URL
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19 October 2019
cites work
Infection of sympathetic and sensory neurones with herpes simplex virus does not elicit a shut-off of cellular protein synthesis: implications for viral latency and herpes vectors
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PubMed Central
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11 July 2018
In vivo characterization of site-directed mutations in the promoter of the herpes simplex virus type 1 latency-associated transcripts
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11 July 2018
Effect of herpes simplex virus type-1 UL41 gene on the stability of mRNA from the cellular genes: beta-actin, fibronectin, glucose transporter-1, and docking protein, and on virus intraperitoneal pathogenicity to newborn mice
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PubMed Central
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11 July 2018
The pseudorabies virus host-shutoff homolog gene: nucleotide sequence and comparison with alphaherpesvirus protein counterparts
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11 July 2018
ICP34.5 mutants of herpes simplex virus type 1 strain 17syn+ are attenuated for neurovirulence in mice and for replication in confluent primary mouse embryo cell cultures
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11 July 2018
Isolation of a herpes simplex virus type 1 mutant with a deletion in the virion host shutoff gene and identification of multiple forms of the vhs (UL41) polypeptide.
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PubMed Central
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11 July 2018
Herpes simplex virus VP16 forms a complex with the virion host shutoff protein vhs
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
The herpes simplex virus regulatory protein ICP27 contributes to the decrease in cellular mRNA levels during infection
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Comparative neurovirulence of herpes simplex virus type 1 strains after peripheral or intracerebral inoculation of BALB/c mice
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Early Virion-associated Suppression of Cellular Protein Synthesis by Herpes Simplex Virus is Accompanied by Inactivation of mRNA
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Regulation of herpesvirus macromolecular synthesis. I. Cascade regulation of the synthesis of three groups of viral proteins
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PubMed Central
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11 July 2018
Macromolecular synthesis in cells infected with herpes simplex virus
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Degradation of cellular mRNAs induced by a virion-associated factor during herpes simplex virus infection of Vero cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Activities of herpes simplex virus type 1 (HSV-1) ICP4 genes specifying nonsense peptides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Effects of herpes simplex virus on mRNA stability
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
A mutant of herpes simplex virus type 1 exhibits increased stability of immediate-early (alpha) mRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
An ICP6::lacZ insertional mutagen is used to demonstrate that the UL52 gene of herpes simplex virus type 1 is required for virus growth and DNA synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Herpes simplex virus virion host shutoff function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
The herpes simplex virus virion host shutoff function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Construction and characterization of a herpes simplex virus type 1 mutant unable to transinduce immediate-early gene expression
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Control of mRNA stability by the virion host shutoff function of herpes simplex virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Herpes simplex virus type 1 ICP27 deletion mutants exhibit altered patterns of transcription and are DNA deficient
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Mapping of herpes simplex virus-1 neurovirulence to gamma 134.5, a gene nonessential for growth in culture
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
Quantitative polymerase chain reaction analysis of herpes simplex virus DNA in ganglia of mice infected with replication-incompetent mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
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11 July 2018
The repressing and enhancing functions of the herpes simplex virus regulatory protein ICP27 map to C-terminal regions and are required to modulate viral gene expression very early in infection
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Comparative DNA sequence analysis of the host shutoff genes of different strains of herpes simplex virus: type 2 strain HG52 encodes a truncated UL41 product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
A herpes simplex virus type 1 mutant containing a nontransinducing Vmw65 protein establishes latent infection in vivo in the absence of viral replication and reactivates efficiently from explanted trigeminal ganglia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Transfer of UL41, the gene controlling virion-associated host cell shutoff, between different strains of herpes simplex virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Investigation of herpes simplex virus type 1 (HSV-1) gene expression and DNA synthesis during the establishment of latent infection by an HSV-1 mutant, in1814, that does not replicate in mouse trigeminal ganglia
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Herpes simplex virus type 1 deletion variants 1714 and 1716 pinpoint neurovirulence-related sequences in Glasgow strain 17+ between immediate early gene 1 and the 'a' sequence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
The promoter of the latency-associated transcripts of herpes simplex virus type 1 contains a functional cAMP-response element: role of the latency-associated transcripts and cAMP in reactivation of viral latency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
In vitro mRNA degradation system to study the virion host shutoff function of herpes simplex virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Molecular basis of latency in pathogenic human viruses
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Detection of latent herpes simplex virus DNA and RNA in human geniculate ganglia by the polymerase chain reaction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Herpes simplex virus type 1 latency-associated transcription unit promotes anatomical site-dependent establishment and reactivation from latency
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Identification and characterization of the virion-induced host shutoff product of herpes simplex virus gene UL41
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Deletion of the VP16 open reading frame of herpes simplex virus type 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Herpes simplex virus thymidine kinase expression in infection of the trigeminal ganglion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Alterations in the protein synthetic apparatus of cells infected with herpes simplex virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Requirement of protein synthesis for the degradation of host mRNA in Friend erythroleukemia cells infected wtih herpes simplex virus type 1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Degradation of cellular mRNA during infection by herpes simplex virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requires functional viral polypeptides
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
11 July 2018
Latent infection with the MS strain of herpes simplex virus type 2 in the mouse following intracerebral inoculation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
24 September 2018
Early and delayed shut-off of host protein synthesis in cells infected with herpes simplex virus
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
24 September 2018
Low levels of herpes simplex virus thymidine- thymidylate kinase are not limiting for sensitivity to certain antiviral drugs or for latency in a mouse model
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=189589
retrieved
24 September 2018
Identifiers
DOI
10.1128/JVI.69.11.6779-6786.1995
0 references
PMC publication ID
189589
1 reference
stated in
Europe PubMed Central
PMC publication ID
189589
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7474089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
PubMed publication ID
7474089
1 reference
stated in
Europe PubMed Central
PMC publication ID
189589
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:7474089%20AND%20SRC:MED&resulttype=core&format=json
retrieved
19 October 2019
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