(Q35850232)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

title

Cytoskeletal defects in Bmpr2-associated pulmonary arterial hypertension (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

main subject

cytoskeleton

0 references

arterial hypertension

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

author name string

Jennifer A Johnson

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Anna R Hemnes

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Manfred Schuster

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Linda J Robinson

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Santhi Gladson

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Hans Loibner

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Susan Bai

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Tom R Blackwell

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Yuji Tada

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Julie W Harral

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Megha Talati

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Kirk B Lane

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

Karen A Fagan

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

James West

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

publication date

16 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

American Journal of Physiology - Lung Cellular and Molecular Physiology

18 January 2020

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

volume

302

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

issue

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

page(s)

L474-84

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

18 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3311512/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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1 reference

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Rho-kinase inhibition alleviates pulmonary hypertension in transgenic mice expressing a dominant-negative type II bone morphogenetic protein receptor gene.

11 July 2018

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Defects in hepatic Notch signaling result in disruption of the communicating intrahepatic bile duct network in mice

11 July 2018

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Cdc42 interaction with N-WASP and Toca-1 regulates membrane tubulation, vesicle formation and vesicle motility: implications for endocytosis

11 July 2018

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The angiotensin-converting enzyme 2/angiogenesis-(1-7)/Mas axis confers cardiopulmonary protection against lung fibrosis and pulmonary hypertension

11 July 2018

1 reference

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Genomewide RNA expression profiling in lung identifies distinct signatures in idiopathic pulmonary arterial hypertension and secondary pulmonary hypertension

11 July 2018

1 reference

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Modulation of Rho guanine exchange factor Lfc activity by protein kinase A-mediated phosphorylation

11 July 2018

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11 July 2018

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Evidence for angiotensin-converting enzyme 2 as a therapeutic target for the prevention of pulmonary hypertension.

11 July 2018

1 reference

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Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways.

11 July 2018

1 reference

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The noncanonical WNT pathway is operative in idiopathic pulmonary arterial hypertension

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

BMP2 induction of actin cytoskeleton reorganization and cell migration requires PI3-kinase and Cdc42 activity.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

Gene expression in BMPR2 mutation carriers with and without evidence of pulmonary arterial hypertension suggests pathways relevant to disease penetrance

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

Mice expressing BMPR2R899X transgene in smooth muscle develop pulmonary vascular lesions

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

Structural implications of mitochondrial dynamics

11 July 2018

1 reference

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KEGG Atlas mapping for global analysis of metabolic pathways

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

Regulation of endothelial junctional permeability

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

Peripheral blood B lymphocytes derived from patients with idiopathic pulmonary arterial hypertension express a different RNA pattern compared with healthy controls: a cross sectional study

11 July 2018

1 reference

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Proteomics of transformed lymphocytes from a family with familial pulmonary arterial hypertension

11 July 2018

1 reference

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11 July 2018

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Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis.

11 July 2018

1 reference

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Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

Direct signaling by the BMP type II receptor via the cytoskeletal regulator LIMK1

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

Quantitative mRNA expression profiling of ACE 2, a novel homologue of angiotensin converting enzyme

11 July 2018

1 reference

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Rac regulates endothelial morphogenesis and capillary assembly

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

Rac regulates vascular endothelial growth factor stimulated motility

11 July 2018

1 reference

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Gene expression patterns in the lungs of patients with primary pulmonary hypertension: a gene microarray analysis

11 July 2018

1 reference

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Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

11 July 2018

1 reference

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11 July 2018

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Elevated matrix metalloprotease and angiostatin levels in integrin alpha 1 knockout mice cause reduced tumor vascularization

11 July 2018

1 reference

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11 July 2018

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11 July 2018

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11 July 2018

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Bone morphogenetic protein receptor II regulates pulmonary artery endothelial cell barrier function

11 July 2018

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24 September 2018

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Cdc42- and Rac1-mediated endothelial lumen formation requires Pak2, Pak4 and Par3, and PKC-dependent signaling.

24 September 2018

1 reference

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Molecular effects of loss of BMPR2 signaling in smooth muscle in a transgenic mouse model of PAH.

24 September 2018

1 reference

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Tenascin-C is induced by mutated BMP type II receptors in familial forms of pulmonary arterial hypertension.

24 September 2018

1 reference

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Bone morphogenetic protein receptor type II C-terminus interacts with c-Src: implication for a role in pulmonary arterial hypertension

24 September 2018

1 reference

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Angiotensin-converting enzyme 2 protects from severe acute lung failure.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

Use of the tetracycline-controlled transcriptional silencer (tTS) to eliminate transgene leak in inducible overexpression transgenic mice.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

Heterozygous germline mutations in BMPR2, encoding a TGF-beta receptor, cause familial primary pulmonary hypertension

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

Ubiquitous expression of marker transgenes in mice and rats.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3311512

Hypertension caused by transgenic overexpression of Rac1

24 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22180660

12 December 2020

inferred from PubMed ID database lookup

Primary pulmonary hypertension a case report including electronmicroscopic study

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22180660

12 December 2020

inferred from PubMed ID database lookup

The Cdc42 and Rac1 GTPases are required for capillary lumen formation in three-dimensional extracellular matrices

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22180660

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1152/AJPLUNG.00202.2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22180660%20AND%20SRC:MED&resulttype=core&format=json

18 January 2020

1 reference