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English
Utilizing the GCN4 leader region to investigate the role of the sequence determinants in nonsense-mediated mRNA decay.
scientific article published in June 1996
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
450218
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8654378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
title
Utilizing the GCN4 leader region to investigate the role of the sequence determinants in nonsense-mediated mRNA decay
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
450218
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8654378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
author name string
M J Ruiz-Echevarria
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
450218
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8654378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
S W Peltz
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
450218
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8654378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
language of work or name
English
0 references
publication date
1 June 1996
1 reference
stated in
Europe PubMed Central
PMC publication ID
450218
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8654378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
published in
The EMBO Journal
1 reference
stated in
Europe PubMed Central
PMC publication ID
450218
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8654378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
volume
15
1 reference
stated in
Europe PubMed Central
PMC publication ID
450218
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8654378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
issue
11
1 reference
stated in
Europe PubMed Central
PMC publication ID
450218
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8654378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
page(s)
2810-2819
1 reference
stated in
Europe PubMed Central
PMC publication ID
450218
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8654378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
cites work
Evidence to implicate translation by ribosomes in the mechanism by which nonsense codons reduce the nuclear level of human triosephosphate isomerase mRNA.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Selective destabilization of short-lived mRNAs with the granulocyte-macrophage colony-stimulating factor AU-rich 3' noncoding region is mediated by a cotranslational mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Stabilization and ribosome association of unspliced pre-mRNAs in a yeast upf1- mutant
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Determination of mRNA fate by different RNA polymerase II promoters
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Premature translational termination triggers mRNA decapping
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Nonsense-mediated mRNA decay in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Identification and characterization of a sequence motif involved in nonsense-mediated mRNA decay
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Characterization of cis-acting sequences and decay intermediates involved in nonsense-mediated mRNA turnover
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Initiation of translation can occur only in a restricted region of the CYC1 mRNA of Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Translational control of GCN4: an in vivo barometer of initiation-factor activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
5' untranslated sequences are required for the translational control of a yeast regulatory gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Evidence for translational regulation of the activator of general amino acid control in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
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11 July 2018
Transformation of intact yeast cells treated with alkali cations
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
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11 July 2018
Polarity and the Degradation of mRNA
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Regulation of the yeast HO gene
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Multiple upstream AUG codons mediate translational control of GCN4.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Eucaryotic RNA polymerase conditional mutant that rapidly ceases mRNA synthesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
The first and fourth upstream open reading frames in GCN4 mRNA have similar initiation efficiencies but respond differently in translational control to change in length and sequence
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Mechanisms of gene regulation in the general control of amino acid biosynthesis in Saccharomyces cerevisiae.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
High efficiency transformation of intact yeast cells using single stranded nucleic acids as a carrier
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Sequences that surround the stop codons of upstream open reading frames in GCN4 mRNA determine their distinct functions in translational control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Translation and a 42-nucleotide segment within the coding region of the mRNA encoded by the MAT alpha 1 gene are involved in promoting rapid mRNA decay in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Suppression of ribosomal reinitiation at upstream open reading frames in amino acid-starved cells forms the basis for GCN4 translational control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Regulation of mRNA turnover in eukaryotic cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
The product of the yeast UPF1 gene is required for rapid turnover of mRNAs containing a premature translational termination codon
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Phosphorylation of initiation factor 2 alpha by protein kinase GCN2 mediates gene-specific translational control of GCN4 in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
An Intron in the Genes for U3 Small Bucleolar RNAs of the Yeast Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Gene products that promote mRNA turnover in Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
Evidence for instability of mRNAs containing AUUUA motifs mediated through translation-dependent assembly of a > 20S degradation complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
cis- and trans-acting suppressors of a translation initiation defect at the cyc1 locus of Saccharomyces cerevisiae
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
11 July 2018
The relationship between eukaryotic translation and mRNA stability. A short upstream open reading frame strongly inhibits translational initiation and greatly accelerates mRNA degradation in the yeast Saccharomyces cerevisiae.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=450218
retrieved
24 September 2018
mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8654378
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identification and characterization of genes that are required for the accelerated degradation of mRNAs containing a premature translational termination codon
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/8654378
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1002/J.1460-2075.1996.TB00641.X
1 reference
stated in
Europe PubMed Central
PMC publication ID
450218
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8654378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
PMC publication ID
450218
1 reference
stated in
Europe PubMed Central
PMC publication ID
450218
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8654378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
PubMed publication ID
8654378
1 reference
stated in
Europe PubMed Central
PMC publication ID
450218
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8654378%20AND%20SRC:MED&resulttype=core&format=json
retrieved
16 October 2019
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