(Q35854005)

English

Identification of homogeneous genetic architecture of multiple genetically correlated traits by block clustering of genome-wide associations

scientific article published in June 2011

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21611967%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Identification of homogeneous genetic architecture of multiple genetically correlated traits by block clustering of genome-wide associations (English)

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21611967%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

genome-wide association study

0 references

Ching Lung Cheung

2

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2 February 2020

Serkalem Demissie

4

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2 February 2020

L. Adrienne Cupples

5

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2 February 2020

Douglas P. Kiel

6

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2 February 2020

7

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2 February 2020

author name string

Mayetri Gupta

1

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2 February 2020

Yi-Hsiang Hsu

3

1 reference

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2 February 2020

publication date

1 June 2011

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2 February 2020

Journal of Bone and Mineral Research

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21611967%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

26

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2 February 2020

6

1 reference

Europe PubMed Central

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2 February 2020

1261-1271

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21611967%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

Synergism between Wnt3a and heparin enhances osteogenesis via a phosphoinositide 3-kinase/Akt/RUNX2 pathway

1 reference

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11 July 2018

Cbl-phosphatidylinositol 3 kinase interaction differentially regulates macrophage colony-stimulating factor-mediated osteoclast survival and cytoskeletal reorganization

1 reference

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11 July 2018

Genome-wide pleiotropy of osteoporosis-related phenotypes: the Framingham Study

1 reference

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11 July 2018

Association of JAG1 with bone mineral density and osteoporotic fractures: a genome-wide association study and follow-up replication studies.

1 reference

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11 July 2018

Systems analysis of bone

1 reference

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11 July 2018

Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Phosphatidylinositol 3 kinase/Akt signal relay cooperates with smad in bone morphogenetic protein-2-induced colony stimulating factor-1 (CSF-1) expression and osteoclast differentiation

1 reference

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11 July 2018

Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies

1 reference

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11 July 2018

Integrated associations of genotypes with multiple blood biomarkers linked to coronary heart disease risk

1 reference

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11 July 2018

Genome-wide association and replication studies identified TRHR as an important gene for lean body mass

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Genome-wide association and follow-up replication studies identified ADAMTS18 and TGFBR3 as bone mass candidate genes in different ethnic groups

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Fibroblast growth factor receptor 2 promotes osteogenic differentiation in mesenchymal cells via ERK1/2 and protein kinase C signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Bivariate genome-wide linkage analysis of femoral bone traits and leg lean mass: Framingham study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Identification of PLCL1 gene for hip bone size variation in females in a genome-wide association study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Prediction of incident hip fracture risk by femur geometry variables measured by hip structural analysis in the study of osteoporotic fractures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Contribution of gender-specific genetic factors to osteoporosis risk.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

A genome wide linkage scan of metacarpal size and geometry in the Framingham Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Bayesian biclustering of gene expression data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Pathway-based approaches for analysis of genomewide association studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Genome-wide association with bone mass and geometry in the Framingham Heart Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Femoral neck BMD is a strong predictor of hip fracture susceptibility in elderly men and women because it detects cortical bone instability: the Rotterdam Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

The human disease network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Increasing the power to detect causal associations by combining genotypic and expression data in segregating populations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Computational approaches to phenotyping: high-throughput phenomics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Proximal hip geometry is linked to several chromosomal regions: genome-wide linkage results from the Framingham Osteoporosis Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Biclustering algorithms for biological data analysis: a survey

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

An estimate of the worldwide prevalence and disability associated with osteoporotic fractures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Principal components analysis corrects for stratification in genome-wide association studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

The expression profile of PKC isoforms during MC3T3-E1 differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Molecular pathways mediating mechanical signaling in bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Interactome-transcriptome analysis reveals the high centrality of genes differentially expressed in lung cancer tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Downregulation of Wnt signaling by increased expression of Dickkopf-1 and -2 is a prerequisite for late-stage osteoblast differentiation of KS483 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Defining the phenotype in human genetic studies: forward genetics and reverse phenotyping

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Sclerostin binds to LRP5/6 and antagonizes canonical Wnt signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Tight clustering: a resampling-based approach for identifying stable and tight patterns in data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Haploview: analysis and visualization of LD and haplotype maps

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

From syndrome families to functional genomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

The modular era of functional genomics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Spectral biclustering of microarray data: coclustering genes and conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Can metacarpal cortical area predict the occurrence of hip fracture in women and men over 3 decades of follow-up? Results from the Framingham Osteoporosis Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Evidence of major gene control of cortical bone loss in humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Biclustering of expression data

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Risk factors for longitudinal bone loss in elderly men and women: the Framingham Osteoporosis Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Meta-analysis of how well measures of bone mineral density predict occurrence of osteoporotic fractures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Continuing bone growth throughout life: A general phenomenon

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Some health benefits of physical activity. The Framingham Study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3312758

11 July 2018

Association of 5' estrogen receptor alpha gene polymorphisms with bone mineral density, vertebral bone area and fracture risk

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Classification of osteoporosis based on bone mineral densities

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Genome screen for quantitative trait loci contributing to normal variation in bone mineral density: the Framingham Study

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Elderly cohort study subjects unable to return for follow-up have lower bone mass than those who can return

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

In vivo short-term precision of hip structure analysis variables in comparison with bone mineral density using paired dual-energy X-ray absorptiometry scans from multi-center clinical trials.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Evidence for a Mendelian gene in a segregation analysis of generalized radiographic osteoarthritis: the Framingham Study.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Accurate assessment of precision errors: how to measure the reproducibility of bone densitometry techniques

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analytical methods.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Multiple phenotype modeling in gene-mapping studies of quantitative traits: power advantages

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Computed radiographic absorptiometry and morphometry in the assessment of postmenopausal bone loss.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Prioritization of candidate disease genes for metabolic syndrome by computational analysis of its defining phenotypes

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Diuretics and bone loss in rats with aldosteronism

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Loss of bone minerals and strength in rats with aldosteronism

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Colocalization of glucocorticoid and mineralocorticoid receptors in human bone

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

The association of Parkinson's disease with bone mineral density and fracture in older women.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Association of Parkinson’s disease with accelerated bone loss, fractures and mortality in older men: the Osteoporotic Fractures in Men (MrOS) study

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Neurotransmitter action in osteoblasts: expression of a functional system for serotonin receptor activation and reuptake

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Using genome-wide pathway analysis to unravel the etiology of complex diseases.

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Endophenotypes as quantitative risk factors for psychiatric disease: rationale and study design.

1 reference

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24 September 2018

Genome scan for quantity of hand osteoarthritis: The Framingham study

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

Relevance of the genes for bone mass variation to susceptibility to osteoporotic fractures and its implications to gene search for complex human diseases

1 reference

https://api.crossref.org/works/10.1002%2FJBMR.333

21 January 2018

The use of multiple sites for the diagnosis of osteoporosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21611967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Femur strength index predicts hip fracture independent of bone density and hip axis length

1 reference

https://pubmed.ncbi.nlm.nih.gov/21611967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A text-mining analysis of the human phenome

1 reference

https://pubmed.ncbi.nlm.nih.gov/21611967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mineralocorticoid receptor activation promotes vascular cell calcification

1 reference

https://pubmed.ncbi.nlm.nih.gov/21611967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age, gender, and body mass effects on quantitative trait loci for bone mineral density: the Framingham Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/21611967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cortical bone loss and measurements of the second metacarpal bone. I. Comparisons between adult Guamanian Chamorros and American Caucasians

1 reference

https://pubmed.ncbi.nlm.nih.gov/21611967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationships between metacarpal morphometry, forearm and vertebral bone density and fractures in post-menopausal women

1 reference

https://pubmed.ncbi.nlm.nih.gov/21611967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How to use ultrasound for risk assessment: a need for defining strategies

1 reference

https://pubmed.ncbi.nlm.nih.gov/21611967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Risk of Wrist Fracture in Women Is Heritable and Is Influenced by Genes That Are Largely Independent of Those Influencing BMD

1 reference

https://pubmed.ncbi.nlm.nih.gov/21611967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phenome connections

1 reference

https://pubmed.ncbi.nlm.nih.gov/21611967

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1002/JBMR.333

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21611967%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21611967%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21611967%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

ResearchGate publication ID

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