(Q35855534)

English

Interferon-gamma sensitizes resistant Ewing's sarcoma cells to tumor necrosis factor apoptosis-inducing ligand-induced apoptosis by up-regulation of caspase-8 without altering chemosensitivity

scientific article published in June 2007

In more languages

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Interferon-gamma sensitizes resistant Ewing's sarcoma cells to tumor necrosis factor apoptosis-inducing ligand-induced apoptosis by up-regulation of caspase-8 without altering chemosensitivity (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

apoptotic process

1 reference

based on heuristic

inferred from title

author name string

Andrej Lissat

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Thomas Vraetz

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Maria Tsokos

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Ruth Klein

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Matthias Braun

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Nino Koutelia

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Paul Fisch

7

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Maria E Romero

8

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Lauren Long

9

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Peter Noellke

10

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Crystal L Mackall

11

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Charlotte M Niemeyer

12

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Udo Kontny

13

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

1 June 2007

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

The American Journal of Pathology

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

170

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1917-1930

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Ewing's sarcoma family of tumors: current management

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Interferon gamma enhances the effectiveness of tumor necrosis factor-related apoptosis-inducing ligand receptor agonists in a xenograft model of Ewing's sarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

TRAIL and its receptors as targets for cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Type I interferon and TNFalpha cooperate with type II interferon for TRAIL induction and triggering of apoptosis in SK-N-MC EWING tumor cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Chemotherapy-induced apoptosis of S-type neuroblastoma cells requires caspase-9 and is augmented by CD95/Fas stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Interferon-γ: an overview of signals, mechanisms and functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Immunomagnetic purging of Ewing's sarcoma from blood and bone marrow: quantitation by real-time polymerase chain reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Caspase-dependent chemotherapy-induced death of glioma cells requires mitochondrial cytochrome c release

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Resistance to TRAIL-induced apoptosis in primitive neuroectodermal brain tumor cells correlates with a loss of caspase-8 expression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Apoptotic responsiveness of the Ewing's sarcoma family of tumours to tumour necrosis factor-related apoptosis-inducing ligand (TRAIL).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

XAGE-1, a new gene that is frequently expressed in Ewing's sarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

FADD is required for DR4- and DR5-mediated apoptosis: lack of trail-induced apoptosis in FADD-deficient mouse embryonic fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Relation of TNF-related apoptosis-inducing ligand (TRAIL) receptor and FLICE-inhibitory protein expression to TRAIL-induced apoptosis of melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Characterization of two receptors for TRAIL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Identification and molecular cloning of two novel receptors for the cytotoxic ligand TRAIL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Control of TRAIL-induced apoptosis by a family of signaling and decoy receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

An antagonist decoy receptor and a death domain-containing receptor for TRAIL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Interferon-gamma modulates a p53-independent apoptotic pathway and apoptosis-related gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

The receptor for the cytotoxic ligand TRAIL

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Inhibition of EWS-FLI-1 fusion protein with antisense oligodeoxynucleotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Identification and characterization of a new member of the TNF family that induces apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

EWS-erg and EWS-Fli1 fusion transcripts in Ewing's sarcoma and primitive neuroectodermal tumors with variant translocations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Long-term treatment of osteopetrosis with recombinant human interferon gamma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Lethal effect of the anti-Fas antibody in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Ewing's sarcoma. Characterization in established cultures and evidence of its histogenesis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Phase I study of i.v. administered recombinant gamma interferon in cancer patients

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Experimental evidence for a neural origin of Ewing's sarcoma of bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Biology of pediatric peripheral neuroectodermal tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

11 July 2018

Tumor necrosis factor-related apoptosis-inducing ligand cooperates with anticancer drugs to overcome chemoresistance in antiapoptotic Bcl-2 family members expressing jurkat cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

24 September 2018

Loss of caspase-8 protein expression correlates with unfavorable survival outcome in childhood medulloblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

24 September 2018

Induction of caspase 8 by interferon gamma renders some neuroblastoma (NB) cells sensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) but reveals that a lack of membrane TR1/TR2 also contributes to TRAIL resistance in NB.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

24 September 2018

Addition of ifosfamide and etoposide to standard chemotherapy for Ewing's sarcoma and primitive neuroectodermal tumor of bone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

24 September 2018

Deregulation of caspase 8 and 10 expression in pediatric tumors and cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

24 September 2018

IFNgamma sensitizes for apoptosis by upregulating caspase-8 expression through the Stat1 pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

24 September 2018

Sensitization for death receptor- or drug-induced apoptosis by re-expression of caspase-8 through demethylation or gene transfer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

24 September 2018

Sensitivity of Ewing's sarcoma to TRAIL-induced apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

24 September 2018

Ewing's sarcoma family tumors are sensitive to tumor necrosis factor-related apoptosis-inducing ligand and express death receptor 4 and death receptor 5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

24 September 2018

Distinct caspase cascades are initiated in receptor-mediated and chemical-induced apoptosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1899433

24 September 2018

Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular regulation of TRAIL-induced apoptosis in human melanoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon gamma induces upregulation and activation of caspases 1, 3, and 8 to produce apoptosis in human erythroid progenitor cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Busulfan, melphalan, and thiotepa with or without total marrow irradiation with hematopoietic stem cell rescue for poor-risk Ewing-Sarcoma-Family tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis induced in normal human hepatocytes by tumor necrosis factor-related apoptosis-inducing ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of caspase-8 expression in highly malignant human neuroblastoma cells correlates with resistance to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-gamma treatment elevates caspase-8 expression and sensitizes human breast tumor cells to a death receptor-induced mitochondria-operated apoptotic program

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absent or reduced expression of the caspase 8 gene occurs frequently in neuroblastoma, but not commonly in Ewing sarcoma or rhabdomyosarcoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytotoxicity of Tumor necrosis factor related apoptosis-inducing ligand towards Ewing's sarcoma cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-gamma modulates TRAIL-mediated apoptosis in human colon carcinoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

EICESS 92 (European Intergroup Cooperative Ewing's Sarcoma Study)-- preliminary results

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TRAIL inhibits tumor growth but is nontoxic to human hepatocytes in chimeric mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/17525260

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.2353/AJPATH.2007.060993

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

0 references

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