(Q35857513)

English

The human cytomegalovirus virion possesses an activated casein kinase II that allows for the rapid phosphorylation of the inhibitor of NF-kappaB, IkappaBalpha

scientific article published on 7 March 2007

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

The human cytomegalovirus virion possesses an activated casein kinase II that allows for the rapid phosphorylation of the inhibitor of NF-kappaB, IkappaBalpha (English)

1 reference

Europe PubMed Central

10 August 2017

0 references

phosphorylation

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

author name string

Maciej T Nogalski

1

1 reference

Europe PubMed Central

10 August 2017

Jagat P Podduturi

2

1 reference

Europe PubMed Central

10 August 2017

Ian B DeMeritt

3

1 reference

Europe PubMed Central

10 August 2017

Liesl E Milford

4

1 reference

Europe PubMed Central

10 August 2017

Andrew D Yurochko

5

1 reference

Europe PubMed Central

10 August 2017

language of work or name

0 references

publication date

7 March 2007

1 reference

Europe PubMed Central

10 August 2017

Journal of Virology

1 reference

Europe PubMed Central

10 August 2017

81

1 reference

Europe PubMed Central

10 August 2017

5305-5314

1 reference

Europe PubMed Central

10 August 2017

10

1 reference

Europe PubMed Central

10 August 2017

Regulation of the transcription and replication cycle of human cytomegalovirus is insensitive to genetic elimination of the cognate NF-kappaB binding sites in the enhancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

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NF-kappaB and IKK as therapeutic targets in cancer

1 reference

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Does cytomegalovirus play a causative role in the development of various inflammatory diseases and cancer?

1 reference

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Development and exploitation of CK2 inhibitors

1 reference

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Role of nuclear factor-kappaB in the immune system and bone

1 reference

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NF-kappaB: linking inflammation and immunity to cancer development and progression

1 reference

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The NF-kappaB signaling pathway in human genetic diseases

1 reference

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Integrin alphavbeta3 is a coreceptor for human cytomegalovirus

1 reference

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Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation

1 reference

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The phosphorylation status of the serine-rich region of the human cytomegalovirus 86-kilodalton major immediate-early protein IE2/IEP86 affects temporal viral gene expression

1 reference

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Role of the proximal enhancer of the major immediate-early promoter in human cytomegalovirus replication

1 reference

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Cellular integrins function as entry receptors for human cytomegalovirus via a highly conserved disintegrin-like domain

1 reference

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Identification of proteins in human cytomegalovirus (HCMV) particles: the HCMV proteome

1 reference

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27 July 2018

Signaling to NF-kappaB

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Activation of the NF-kappaB pathway in human cytomegalovirus-infected cells is necessary for efficient transactivation of the major immediate-early promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

NF-kappaB- and c-Jun-dependent regulation of human cytomegalovirus immediate-early gene enhancer/promoter in response to lipopolysaccharide and bacterial CpG-oligodeoxynucleotides in macrophage cell line RAW 264.7.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Neutrality of the canonical NF-kappaB-dependent pathway for human and murine cytomegalovirus transcription and replication in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Epidermal growth factor receptor is a cellular receptor for human cytomegalovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

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Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

The human cytomegalovirus major immediate-early enhancer determines the efficiency of immediate-early gene transcription and viral replication in permissive cells at low multiplicity of infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

An essential role of the enhancer for murine cytomegalovirus in vivo growth and pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Protein kinase CK2 promotes aberrant activation of nuclear factor-kappaB, transformed phenotype, and survival of breast cancer cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Protein kinase CK2: structure, regulation and role in cellular decisions of life and death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Phosphorylation by the protein kinase CK2 promotes calpain-mediated degradation of IkappaBalpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Structural features underlying selective inhibition of protein kinase CK2 by ATP site-directed tetrabromo-2-benzotriazole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

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Do pathogens accelerate atherosclerosis?

1 reference

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27 July 2018

Global modulation of cellular transcription by human cytomegalovirus is initiated by viral glycoprotein B.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Allogeneic transplantation induces expression of cytomegalovirus immediate-early genes in vivo: a model for reactivation from latency

1 reference

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27 July 2018

The human cytomegalovirus major immediate-early distal enhancer region is required for efficient viral replication and immediate-early gene expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Identification by in vivo genomic footprinting of a transcriptional switch containing NF-kappaB and Sp1 that regulates the IkappaBalpha promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

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Nuclear IkappaBbeta maintains persistent NF-kappaB activation in HIV-1-infected myeloid cells

1 reference

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27 July 2018

Engagement of the cellular receptor for glycoprotein B of human cytomegalovirus activates the interferon-responsive pathway

1 reference

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27 July 2018

IkappaB-mediated inhibition of virus-induced beta interferon transcription

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Polo-like kinase 1 as a target for human cytomegalovirus pp65 lower matrix protein

1 reference

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Steady-state plasma membrane expression of human cytomegalovirus gB is determined by the phosphorylation state of Ser900

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

The human cytomegalovirus UL55 (gB) and UL75 (gH) glycoprotein ligands initiate the rapid activation of Sp1 and NF-kappaB during infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Induction of the transcription factor Sp1 during human cytomegalovirus infection mediates upregulation of the p65 and p105/p50 NF-kappaB promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Human cytomegalovirus cell tropism and pathogenesis

1 reference

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The role of infection in restenosis and atherosclerosis: focus on cytomegalovirus

1 reference

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27 July 2018

Constitutive phosphorylation of IkappaBalpha by casein kinase II occurs preferentially at serine 293: requirement for degradation of free IkappaBalpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Phosphorylation of IkappaBalpha in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Casein kinase II phosphorylates I kappa B alpha at S-283, S-289, S-293, and T-291 and is required for its degradation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Increased levels of sequence-specific DNA-binding proteins in human cytomegalovirus-infected cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Protein kinases. 4. Protein kinase CK2: an enzyme with multiple substrates and a puzzling regulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Constitutive phosphorylation of I kappa B alpha by casein kinase II.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Human cytomegalovirus upregulates NF-kappa B activity by transactivating the NF-kappa B p105/p50 and p65 promoters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Promoter-regulatory region of the major immediate early gene of human cytomegalovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

Organization and expression of the immediate early genes of human cytomegalovirus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

27 July 2018

NF-kappa B activation of the cytomegalovirus enhancer is mediated by a viral transactivator and by T cell stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

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Human cytomegalovirus ie1 transactivates the alpha promoter-enhancer via an 18-base-pair repeat element.

1 reference

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Association of ICP0 but not ICP27 with purified virions of herpes simplex virus type 1

1 reference

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Prolonged activation of NF-kappaB by human cytomegalovirus promotes efficient viral replication and late gene expression

1 reference

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Proteins of purified Epstein-Barr virus

1 reference

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Expanded nuclear roles for IkappaBs

1 reference

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Human cytomegalovirus stimulates cellular IKK2 activity and requires the enzyme for productive replication.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

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Proteasome inhibitors: a novel tool to suppress human cytomegalovirus replication and virus-induced immune modulation.

1 reference

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Human cytomegalovirus elicits a coordinated cellular antiviral response via envelope glycoprotein B.

1 reference

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CK2 Is a C-Terminal IκB Kinase Responsible for NF-κB Activation during the UV Response

1 reference

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24 September 2018

One-thousand-and-one substrates of protein kinase CK2?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

24 September 2018

NF-kappaB--a potential therapeutic target for inhibition of human cytomegalovirus (re)activation?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1900216

24 September 2018

Human cytomegalovirus infection and expression in human malignant glioma.

1 reference

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24 September 2018

Stimulation of the human cytomegalovirus IE enhancer/promoter in HL-60 cells by TNFalpha is mediated via induction of NF-kappaB.

1 reference

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24 September 2018

Disruption of NF-kappa B signaling and chemokine gene activation by retroviral mediated expression of IKK gamma/NEMO mutants

1 reference

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24 September 2018

Selectivity of 4,5,6,7-tetrabromobenzotriazole, an ATP site-directed inhibitor of protein kinase CK2 ('casein kinase-2').

1 reference

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24 September 2018

Immunohistochemical detection of an immediate early antigen of human cytomegalovirus in normal tissues

1 reference

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24 September 2018

NF- B activation can mediate inhibition of human cytomegalovirus replication

1 reference

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14 November 2018

Human cytomegalovirus binding to human monocytes induces immunoregulatory gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High rate of concurrent genital infections with human cytomegalovirus and human papillomaviruses in cervical cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Widespread presence of histologically occult cytomegalovirus

1 reference

https://pubmed.ncbi.nlm.nih.gov/17344282

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.02382-06

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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