(Q35867942)

English

The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector

scientific article published on 13 February 2012

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scholarly article

1 reference

Europe PubMed Central

10 August 2017

The RalB small GTPase mediates formation of invadopodia through a GTPase-activating protein-independent function of the RalBP1/RLIP76 effector (English)

1 reference

Europe PubMed Central

10 August 2017

1 reference

based on heuristic

inferred from title

author name string

Nicole F Neel

1

1 reference

Europe PubMed Central

10 August 2017

Kent L Rossman

2

1 reference

Europe PubMed Central

10 August 2017

Timothy D Martin

3

1 reference

Europe PubMed Central

10 August 2017

Tikvah K Hayes

4

1 reference

Europe PubMed Central

10 August 2017

Jen Jen Yeh

5

1 reference

Europe PubMed Central

10 August 2017

Channing J Der

6

1 reference

Europe PubMed Central

10 August 2017

language of work or name

0 references

publication date

13 February 2012

1 reference

Europe PubMed Central

10 August 2017

Molecular and Cellular Biology

1 reference

Europe PubMed Central

10 August 2017

32

1 reference

Europe PubMed Central

10 August 2017

8

1 reference

Europe PubMed Central

10 August 2017

1374-1386

1 reference

Europe PubMed Central

10 August 2017

PIK3CA mutations frequently coexist with RAS and BRAF mutations in patients with advanced cancers

1 reference

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11 July 2018

Degrading devices: invadosomes in proteolytic cell invasion

1 reference

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The RalGEF-Ral Effector Signaling Network: The Road Less Traveled for Anti-Ras Drug Discovery

1 reference

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11 July 2018

Phosphoinositide 3-kinase signaling pathway mediated by p110α regulates invadopodia formation

1 reference

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Ras history: The saga continues

1 reference

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11 July 2018

Invadosome regulation by adhesion signaling.

1 reference

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The guanine nucleotide exchange factor Arhgef5 plays crucial roles in Src-induced podosome formation

1 reference

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Nucleating actin for invasion

1 reference

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RalB and the exocyst mediate the cellular starvation response by direct activation of autophagosome assembly

1 reference

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Ras effector switching promotes divergent cell fates in C. elegans vulval patterning

1 reference

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Activation and involvement of Ral GTPases in colorectal cancer

1 reference

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Aberrant overexpression of the Rgl2 Ral small GTPase-specific guanine nucleotide exchange factor promotes pancreatic cancer growth through Ral-dependent and Ral-independent mechanisms

1 reference

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11 July 2018

The RalB-RLIP76 Complex Reveals a Novel Mode of Ral-Effector Interaction

1 reference

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Sec5 and Exo84 foster oncogenic ras-mediated tumorigenesis

1 reference

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11 July 2018

Aurora-A phosphorylates, activates, and relocalizes the small GTPase RalA

1 reference

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11 July 2018

Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1

1 reference

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The role of the exocyst in matrix metalloproteinase secretion and actin dynamics during tumor cell invadopodia formation

1 reference

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11 July 2018

K-Ras promotes angiogenesis mediated by immortalized human pancreatic epithelial cells through mitogen-activated protein kinase signaling pathways

1 reference

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A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene

1 reference

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Synthetic lethal interaction between oncogenic KRAS dependency and STK33 suppression in human cancer cells

1 reference

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11 July 2018

A gene expression signature associated with "K-Ras addiction" reveals regulators of EMT and tumor cell survival

1 reference

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11 July 2018

ADP-ribosylation factor 6 regulates tumorigenic and invasive properties in vivo

1 reference

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11 July 2018

Invadopodia: specialized tumor cell structures for the focal degradation of the extracellular matrix

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318593

11 July 2018

RLIP76: A novel glutathione-conjugate and multi-drug transporter

1 reference

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11 July 2018

TGF-beta induces formation of F-actin cores and matrix degradation in human breast cancer cells via distinct signaling pathways

1 reference

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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

1 reference

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11 July 2018

Distinct roles of RalA and RalB in the progression of cytokinesis are supported by distinct RalGEFs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318593

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Mapping proteolytic cancer cell-extracellular matrix interfaces

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318593

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Ras oncogenes: split personalities

1 reference

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The interaction of IQGAP1 with the exocyst complex is required for tumor cell invasion downstream of Cdc42 and RhoA.

1 reference

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Assembly and biological role of podosomes and invadopodia

1 reference

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Ral GTPases and cancer: linchpin support of the tumorigenic platform

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Release of autoinhibition of ASEF by APC leads to CDC42 activation and tumor suppression

1 reference

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K-Ras promotes growth transformation and invasion of immortalized human pancreatic cells by Raf and phosphatidylinositol 3-kinase signaling

1 reference

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11 July 2018

Divergent roles for RalA and RalB in malignant growth of human pancreatic carcinoma cells.

1 reference

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11 July 2018

RalB GTPase-mediated activation of the IkappaB family kinase TBK1 couples innate immune signaling to tumor cell survival

1 reference

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Molecular mechanisms of metastasis

1 reference

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11 July 2018

Use of retrovirus expression of interfering RNA to determine the contribution of activated K-Ras and ras effector expression to human tumor cell growth.

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Activation of RalA is critical for Ras-induced tumorigenesis of human cells.

1 reference

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Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin

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Identification of membrane-anchoring domains of RLIP76 using deletion mutant analyses

1 reference

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Renewing the conspiracy theory debate: does Raf function alone to mediate Ras oncogenesis?

1 reference

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Foot and mouth: podosomes, invadopodia and circular dorsal ruffles

1 reference

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ADP-ribosylation factor 6 regulates tumor cell invasion through the activation of the MEK/ERK signaling pathway

1 reference

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Dissecting the metastatic cascade

1 reference

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Requirement for Arf6 in breast cancer invasive activities

1 reference

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Oncogenic Ras and its role in tumor cell invasion and metastasis

1 reference

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Involvement of Cdc42 and Rac small G proteins in invadopodia formation of RPMI7951 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318593

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Ral GTPases regulate exocyst assembly through dual subunit interactions

1 reference

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Transport of glutathione conjugates and chemotherapeutic drugs by RLIP76 (RALBP1): a novel link between G-protein and tyrosine kinase signaling and drug resistance

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RLIP, an effector of the Ral GTPases, is a platform for Cdk1 to phosphorylate epsin during the switch off of endocytosis in mitosis

1 reference

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HSF-1 interacts with Ral-binding protein 1 in a stress-responsive, multiprotein complex with HSP90 in vivo

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Regulation of endocytosis of activin type II receptors by a novel PDZ protein through Ral/Ral-binding protein 1-dependent pathway

1 reference

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Ral-GTPase influences the regulation of the readily releasable pool of synaptic vesicles.

1 reference

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Novel function of human RLIP76: ATP-dependent transport of glutathione conjugates and doxorubicin

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RLIP76, an effector of the GTPase Ral, interacts with the AP2 complex: involvement of the Ral pathway in receptor endocytosis

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Identification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of Ral

1 reference

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An Eps homology (EH) domain protein that binds to the Ral-GTPase target, RalBP1

1 reference

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11 July 2018

The post-translational modifications of Ral and Rac1 are important for the action of Ral-binding protein 1, a putative effector protein of Ral.

1 reference

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11 July 2018

A putative effector of Ral has homology to Rho/Rac GTPase activating proteins

1 reference

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Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity

1 reference

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Identification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPases

1 reference

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Pancreatic Cancer

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Real-time in vitro measurement of intrinsic and Ras GAP-mediated GTP hydrolysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22331470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The exocyst is a Ral effector complex

1 reference

https://pubmed.ncbi.nlm.nih.gov/22331470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/MCB.06291-11

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

1 reference

Europe PubMed Central

10 August 2017

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