(Q35868173)

10 August 2017

Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces β-secretase (BACE1) levels and Aβ generation (English)

1 reference

10 August 2017

Yun Ding

1

1 reference

10 August 2017

Mi Hee Ko

2

1 reference

10 August 2017

Mariana Pehar

3

1 reference

10 August 2017

Frank Kotch

4

1 reference

10 August 2017

Noel R Peters

5

1 reference

10 August 2017

Yun Luo

6

1 reference

10 August 2017

Shahriar M Salamat

7

1 reference

10 August 2017

Luigi Puglielli

8

1 reference

10 August 2017

language of work or name

English

0 references

publication date

20 January 2012

1 reference

Journal of Biological Chemistry

10 August 2017

1 reference

10 August 2017

287

1 reference

10 August 2017

11

1 reference

10 August 2017

8424-8433

1 reference

Glial and neuronal control of brain blood flow

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

AT-1 is the ER membrane acetyl-CoA transporter and is essential for cell viability

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

Altered longevity-assurance activity of p53:p44 in the mouse causes memory loss, neurodegeneration and premature death

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

Microglia in neurodegenerative disease

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

Alzheimer's disease-like pathological features in transgenic mice expressing the APP intracellular domain.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

Two endoplasmic reticulum (ER)/ER Golgi intermediate compartment-based lysine acetyltransferases post-translationally regulate BACE1 levels

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

PCSK9 is required for the disposal of non-acetylated intermediates of the nascent membrane protein BACE1.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

An aging pathway controls the TrkA to p75NTR receptor switch and amyloid beta-peptide generation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

BACE1 is the major beta-secretase for generation of Abeta peptides by neurons

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

Mice deficient in BACE1, the Alzheimer's beta-secretase, have normal phenotype and abolished beta-amyloid generation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318698

Aging of the brain, neurotrophin signaling, and Alzheimer's disease: is IGF1-R the common culprit?

27 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.310136

Evolution of amyloid: what normal protein folding may tell us about fibrillogenesis and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.310136

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.310136

Protofibrils, the unifying toxic molecule of neurodegenerative disorders?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.310136

Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.310136

Drugs: a tangled web of targets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.310136

A reversible form of lysine acetylation in the ER and Golgi lumen controls the molecular stabilization of BACE1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.310136

The sterol carrier protein SCP-x/pro-SCP-2 gene has transcriptional activity and regulates the Alzheimer disease gamma-secretase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.310136

Modulation of mammalian life span by the short isoform of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.310136

Neuroglial roots of neurodegenerative diseases?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.310136

HATs and HDACs: from structure, function and regulation to novel strategies for therapy and prevention

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.310136

21 January 2018

Identifiers

DOI

10.1074/JBC.M111.310136

1 reference

10 August 2017

1 reference

10 August 2017

1 reference