(Q35868288)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235115%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

title

Trimeric, coiled-coil extension on peptide fusion inhibitor of HIV-1 influences selection of resistance pathways (English)

1 reference

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20 January 2020

5

1 reference

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20 January 2020

author name string

Min Zhuang

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235115%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Wei Wang

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235115%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Christopher J De Feo

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235115%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

Russell Vassell

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235115%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

language of work or name

English

0 references

publication date

10 January 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235115%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

number of pages

13

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

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20 January 2020

volume

287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235115%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

issue

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235115%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

page(s)

8297-8309

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235115%20AND%20SRC:MED&resulttype=core&format=json

Design of a Potent D-Peptide HIV-1 Entry Inhibitor with a Strong Barrier to Resistance

20 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Characterization of HIV-1 resistance to a fusion inhibitor, N36, derived from the gp41 amino-terminal heptad repeat

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Human immunodeficiency virus type 1 variants resistant to first- and second-version fusion inhibitors and cytopathic in ex vivo human lymphoid tissue

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Impact of human immunodeficiency virus type 1 gp41 amino acid substitutions selected during enfuvirtide treatment on gp41 binding and antiviral potency of enfuvirtide in vitro

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Human immunodeficiency virus (HIV) gp41 escape mutants: cross-resistance to peptide inhibitors of HIV fusion and altered receptor activation of gp120.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Resistance to enfuvirtide, the first HIV fusion inhibitor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Alpha-complementation assay for HIV envelope glycoprotein-mediated fusion

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Inhibiting HIV-1 entry with fusion inhibitors

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Direct evidence that C-peptide inhibitors of human immunodeficiency virus type 1 entry bind to the gp41 N-helical domain in receptor-activated viral envelope

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Peptides trap the human immunodeficiency virus type 1 envelope glycoprotein fusion intermediate at two sites

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

The prefusogenic intermediate of HIV-1 gp41 contains exposed C-peptide regions.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide region

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Protein design of an HIV-1 entry inhibitor

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Helical interactions in the HIV-1 gp41 core reveal structural basis for the inhibitory activity of gp41 peptides

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Monomer-trimer equilibrium of the ectodomain of SIV gp41: insight into the mechanism of peptide inhibition of HIV infection

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

HIV entry and its inhibition

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Capture of an early fusion-active conformation of HIV-1 gp41

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Effects of CCR5 and CD4 cell surface concentrations on infections by macrophagetropic isolates of human immunodeficiency virus type 1.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Atomic structure of a thermostable subdomain of HIV-1 gp41

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Atomic structure of the ectodomain from HIV-1 gp41

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

HIV-1 membrane fusion mechanism: structural studies of the interactions between biologically-active peptides from gp41.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Thermodynamics of denaturation of barstar: evidence for cold denaturation and evaluation of the interaction with guanidine hydrochloride.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

CD26 expression correlates with entry, replication and cytopathicity of monocytotropic HIV–1 strains in a T–cell line

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Determination of the helix and beta form of proteins in aqueous solution by circular dichroism.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Mutational analysis of the human immunodeficiency virus type 1 Rev transactivator: essential residues near the amino terminus

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3318747

Mechanisms of viral membrane fusion and its inhibition

27 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324483

Membrane fusion mediated by human immunodeficiency virus envelope glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324483

Core structure of gp41 from the HIV envelope glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324483

The crystal structure of the SIV gp41 ectodomain at 1.47 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324483

Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324483

Evolution of the gp41 env region in HIV-infected patients receiving T-20, a fusion inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324483

Design of a novel peptide inhibitor of HIV fusion that disrupts the internal trimeric coiled-coil of gp41.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324483

Identification of a critical motif for the human immunodeficiency virus type 1 (HIV-1) gp41 core structure: implications for designing novel anti-HIV fusion inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324483

Selection with a peptide fusion inhibitor corresponding to the first heptad repeat of HIV-1 gp41 identifies two genetic pathways conferring cross-resistance to peptide fusion inhibitors corresponding to the first and second heptad repeats (HR1 and H

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324483

A trimeric structural domain of the HIV-1 transmembrane glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324483

Kinetic dependence to HIV-1 entry inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324483

Contribution of intrinsic reactivity of the HIV-1 envelope glycoproteins to CD4-independent infection and global inhibitor sensitivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.324483

HIV gp41 C-terminal heptad repeat contains multifunctional domains. Relation to mechanisms of action of anti-HIV peptides

21 January 2018

1 reference

12 December 2020

Model for the structure of the HIV gp41 ectodomain: insight into the intermolecular interactions of the gp41 loop

1 reference

12 December 2020

A trimeric structural subdomain of the HIV-1 transmembrane glycoprotein

1 reference

12 December 2020

Steric accessibility of the HIV-1 gp41 N-trimer region

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M111.324483

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235115%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22235115%20AND%20SRC:MED&resulttype=core&format=json

20 January 2020

PubMed publication ID

22235115

1 reference