(Q35871546)

10 August 2017

PARP-1 inhibition as a targeted strategy to treat Ewing's sarcoma (English)

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10 August 2017

9

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10 August 2017

J Chad Brenner

1

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10 August 2017

Felix Y Feng

2

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10 August 2017

Sumin Han

3

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10 August 2017

Sonam Patel

4

1 reference

10 August 2017

Siddharth V Goyal

5

1 reference

10 August 2017

Laura M Bou-Maroun

6

1 reference

10 August 2017

Meilan Liu

7

1 reference

10 August 2017

Robert Lonigro

8

1 reference

10 August 2017

Scott A Tomlins

10

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10 August 2017

Arul M Chinnaiyan

11

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10 August 2017

language of work or name

English

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publication date

27 January 2012

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10 August 2017

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10 August 2017

72

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10 August 2017

7

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10 August 2017

1608-1613

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Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer

10 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

PARP inhibition: PARP1 and beyond

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

Translocations in epithelial cancers

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

ABT-888, an orally active poly(ADP-ribose) polymerase inhibitor that potentiates DNA-damaging agents in preclinical tumor models

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

Specific killing of BRCA2-deficient tumours with inhibitors of poly(ADP-ribose) polymerase

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

EWS-FLI1 target genes recovered from Ewing's sarcoma chromatin

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

Ewing's sarcoma: diagnostic, prognostic, and therapeutic implications of molecular abnormalities

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

Poly(ADP-ribose) polymerase turnover alterations do not contribute to PARP overexpression in Ewing's sarcoma cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

DNA binding domain-independent pathways are involved in EWS/FLI1-mediated oncogenesis.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

Treatment strategies for metastatic Ewing's sarcoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

Regulation of the human poly(ADP-ribose) polymerase promoter by the ETS transcription factor

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing's sarcoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

Mesenchymal Stem Cells and the Origin of Ewing's Sarcoma

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

Temozolomide and intravenous irinotecan for treatment of advanced Ewing sarcoma

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

NAD+-dependent modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3319786

10.1158/0008-5472.CAN-11-3648

24 September 2018

Identifiers

DOI

1 reference

10 August 2017

1 reference

10 August 2017

PubMed publication ID

22287547

1 reference