(Q35876963)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22271446%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

title

JAM-A protects from thrombosis by suppressing integrin αIIbβ3-dependent outside-in signaling in platelets (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22271446%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

2

1 reference

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21 January 2020

author name string

Meghna U Naik

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22271446%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Lawrence F Brass

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22271446%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Ulhas P Naik

series ordinal

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22271446%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

language of work or name

English

0 references

publication date

23 January 2012

1 reference

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21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22271446%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

volume

119

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22271446%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

issue

14

1 reference

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21 January 2020

page(s)

3352-3360

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22271446%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

21 January 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3321861/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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Signaling during platelet adhesion and activation

27 July 2018

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G protein subunit Galpha13 binds to integrin alphaIIbbeta3 and mediates integrin "outside-in" signaling

27 July 2018

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Homophilic adhesion and CEACAM1-S regulate dimerization of CEACAM1-L and recruitment of SHP-2 and c-Src

27 July 2018

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Endothelial cell specific adhesion molecule (ESAM) localizes to platelet-platelet contacts and regulates thrombus formation in vivo

27 July 2018

1 reference

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Platelet receptors and signaling in the dynamics of thrombus formation.

27 July 2018

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CEACAM1 negatively regulates platelet-collagen interactions and thrombus growth in vitro and in vivo

27 July 2018

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Antithrombotic effects of targeting alphaIIbbeta3 signaling in platelets

27 July 2018

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Identification of FcgammaRIIa as the ITAM-bearing receptor mediating alphaIIbbeta3 outside-in integrin signaling in human platelets

27 July 2018

1 reference

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RGT, a synthetic peptide corresponding to the integrin beta 3 cytoplasmic C-terminal sequence, selectively inhibits outside-in signaling in human platelets by disrupting the interaction of integrin alpha IIb beta 3 with Src kinase

27 July 2018

1 reference

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JAM-A is present in mammalian spermatozoa where it is essential for normal motility.

27 July 2018

1 reference

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Involvement of Src kinases and PLCgamma2 in clot retraction

27 July 2018

1 reference

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Platelet PECAM-1 inhibits thrombus formation in vivo.

27 July 2018

1 reference

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Junctional adhesion molecule 1 regulates epithelial cell morphology through effects on beta1 integrins and Rap1 activity.

27 July 2018

1 reference

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Mer receptor tyrosine kinase signaling participates in platelet function

27 July 2018

1 reference

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Junctional adhesion molecule 1 (JAM-1)

27 July 2018

1 reference

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Annexin II regulates fibrin homeostasis and neoangiogenesis in vivo

27 July 2018

1 reference

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The negative regulation of platelet function: extending the role of the ITIM.

27 July 2018

1 reference

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Two regions of the human platelet F11-receptor (F11R) are critical for platelet aggregation, potentiation and adhesion

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton

27 July 2018

1 reference

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Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cells

27 July 2018

1 reference

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Platelet endothelial cell adhesion molecule-1 serves as an inhibitory receptor that modulates platelet responses to collagen

27 July 2018

1 reference

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Src homology 2 domain-containing protein-tyrosine phosphatases, SHP-1 and SHP-2, are required for platelet endothelial cell adhesion molecule-1/CD31-mediated inhibitory signaling

27 July 2018

1 reference

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Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.

27 July 2018

1 reference

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Cloning of the human platelet F11 receptor: a cell adhesion molecule member of the immunoglobulin superfamily involved in platelet aggregation

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

Signaling through platelet integrin alpha IIb beta 3: inside-out, outside-in, and sideways

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

The carboxyl-terminal region of biliary glycoprotein controls its tyrosine phosphorylation and association with protein-tyrosine phosphatases SHP-1 and SHP-2 in epithelial cells

27 July 2018

1 reference

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27 July 2018

1 reference

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Mechanisms of platelet activation by a stimulatory antibody: cross-linking of a novel platelet receptor for monoclonal antibody F11 with the Fc gamma RII receptor

27 July 2018

1 reference

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Activation of human platelets by a stimulatory monoclonal antibody

27 July 2018

1 reference

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Platelets at work in primary hemostasis.

27 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

A molecular switch that controls cell spreading and retraction

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

Deletion of JAM-A causes morphological defects in the corneal epithelium.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

Signaling pathways of the F11 receptor (F11R; a.k.a. JAM-1, JAM-A) in human platelets: F11R dimerization, phosphorylation and complex formation with the integrin GPIIIa

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

Association of CIB with GPIIb/IIIa during outside-in signaling is required for platelet spreading on fibrinogen

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

Protection against thrombosis in mice lacking PAR3.

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

Flow cytometric detection of activated mouse integrin alphaIIbbeta3 with a novel monoclonal antibody

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

Heterogeneity of endothelial junctions is reflected by differential expression and specific subcellular localization of the three JAM family members

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

Platelet endothelial cell adhesion molecule-1 is a negative regulator of platelet-collagen interactions

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression

24 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321861

Sheep, pig, and human platelet-material interactions with model cardiovascular biomaterials

24 September 2018

1 reference

12 December 2020

JAM-A expression during embryonic development

1 reference

12 December 2020

Fibroblast growth factor-2 failed to induce angiogenesis in junctional adhesion molecule-A-deficient mice

1 reference

12 December 2020

Integrin affinity modulation

1 reference

12 December 2020

CIB1 deficiency results in impaired thrombosis: the potential role of CIB1 in outside-in signaling through integrin alpha IIb beta 3

1 reference

12 December 2020

Junctional adhesion molecule (JAM) is phosphorylated by protein kinase C upon platelet activation

1 reference

12 December 2020

Real-time in vivo imaging of platelets, tissue factor and fibrin during arterial thrombus formation in the mouse

1 reference

12 December 2020

F11-receptor (F11R/JAM) mediates platelet adhesion to endothelial cells: role in inflammatory thrombosis

1 reference

12 December 2020

Signaling through JAM-1 and αvβ3 is required for the angiogenic action of bFGF: dissociation of the JAM-1 and αvβ3 complex

1 reference

12 December 2020

10.1182/BLOOD-2011-12-397398

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22271446%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22271446%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

22271446

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22271446%20AND%20SRC:MED&resulttype=core&format=json