(Q35879480)

10 August 2017

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title

Transgenesis and cardiac energetics: new insights into cardiac metabolism (English)

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10 August 2017

Joanne S Ingwall

1

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10 August 2017

publication date

1 September 2004

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Journal of Molecular and Cellular Cardiology

10 August 2017

published in

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10 August 2017

volume

37

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10 August 2017

issue

3

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10 August 2017

page(s)

613-623

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The possible role of the mitochondrial bound creatine kinase in regulation of mitochondrial respiration

10 August 2017

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Regulation of fatty acid oxidation in the mammalian heart in health and disease

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Cardiac and adipose tissue abnormalities but not diabetes in mice deficient in GLUT4

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Cardiac-specific overexpression of GLUT1 prevents the development of heart failure attributable to pressure overload in mice

7 January 2021

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An increase in the myocardial PCr/ATP ratio in GLUT4 null mice

7 January 2021

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7 January 2021

based on heuristic

Responses of GLUT4-deficient hearts to ischemia underscore the importance of glycolysis

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https://api.crossref.org/works/10.1016%2FJ.YJMCC.2004.05.020

Preservation of glucose metabolism in hypertrophic GLUT4-null hearts

7 January 2021

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Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression

7 January 2021

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PPAR signaling in the control of cardiac energy metabolism

7 January 2021

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Constitutive regulation of cardiac fatty acid metabolism through peroxisome proliferator-activated receptor alpha associated with age-dependent cardiac toxicity

7 January 2021

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The cardiac phenotype induced by PPARalpha overexpression mimics that caused by diabetes mellitus

7 January 2021

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Reactivation of peroxisome proliferator-activated receptor alpha is associated with contractile dysfunction in hypertrophied rat heart

7 January 2021

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A role for peroxisome proliferator-activated receptor alpha (PPARalpha ) in the control of cardiac malonyl-CoA levels: reduced fatty acid oxidation rates and increased glucose oxidation rates in the hearts of mice lacking PPARalpha are associated wi

7 January 2021

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Bioenergetic analysis of peroxisome proliferator-activated receptor gamma coactivators 1alpha and 1beta (PGC-1alpha and PGC-1beta) in muscle cells

7 January 2021

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Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

7 January 2021

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A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis

7 January 2021

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7 January 2021

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7 January 2021

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Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner

7 January 2021

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7 January 2021

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AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation

7 January 2021

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The AMP-activated protein kinase--fuel gauge of the mammalian cell?

7 January 2021

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Increased adenosine monophosphate-activated protein kinase activity in rat hearts with pressure-overload hypertrophy

7 January 2021

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Chronic activation of AMP kinase results in NRF-1 activation and mitochondrial biogenesis

7 January 2021

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Alterations in fatty acid oxidation during reperfusion of the heart after myocardial ischemia

7 January 2021

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AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target.

7 January 2021

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5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle

7 January 2021

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Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

7 January 2021

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Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle.

7 January 2021

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Is creatine kinase a target for AMP-activated protein kinase in the heart?

7 January 2021

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Transgenic mice overexpressing mutant PRKAG2 define the cause of Wolff-Parkinson-White syndrome in glycogen storage cardiomyopathy.

7 January 2021

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Glucose metabolism and energy homeostasis in mouse hearts overexpressing dominant negative alpha2 subunit of AMP-activated protein kinase

7 January 2021

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Cardiac energetics: sense and nonsense

7 January 2021

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ATPase activity of myosin correlated with speed of muscle shortening

7 January 2021

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Ablation of the murine alpha myosin heavy chain gene leads to dosage effects and functional deficits in the heart

7 January 2021

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Expression of the beta (slow)-isoform of MHC in the adult mouse heart causes dominant-negative functional effects

7 January 2021

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Analysis of myosin heavy chain functionality in the heart.

7 January 2021

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Functional significance of cardiac myosin essential light chain isoform switching in transgenic mice

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Effects of total replacement of atrial myosin light chain-2 with the ventricular isoform in atrial myocytes of transgenic mice

7 January 2021

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Abnormal cardiac structure and function in mice expressing nonphosphorylatable cardiac regulatory myosin light chain 2

7 January 2021

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Phenotypical features of long Q-T syndrome in transgenic mice expressing human Na-K-ATPase alpha(3)-isoform in hearts

7 January 2021

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A molecular basis for familial hypertrophic cardiomyopathy: a beta cardiac myosin heavy chain gene missense mutation

7 January 2021

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31P NMR spectroscopy detects metabolic abnormalities in asymptomatic patients with hypertrophic cardiomyopathy

7 January 2021

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Differences in cardiac energetics between patients with familial and nonfamilial hypertrophic cardiomyopathy

7 January 2021

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Diastolic dysfunction and altered energetics in the alphaMHC403/+ mouse model of familial hypertrophic cardiomyopathy

7 January 2021

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Decreased energetics in murine hearts bearing the R92Q mutation in cardiac troponin T

7 January 2021

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Hypertrophic cardiomyopathy due to sarcomeric gene mutations is characterized by impaired energy metabolism irrespective of the degree of hypertrophy

7 January 2021

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Hypertrophic cardiomyopathy:a paradigm for myocardial energy depletion

7 January 2021

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Mutations in the gamma(2) subunit of AMP-activated protein kinase cause familial hypertrophic cardiomyopathy: evidence for the central role of energy compromise in disease pathogenesis

7 January 2021

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Novel PRKAG2 mutation responsible for the genetic syndrome of ventricular preexcitation and conduction system disease with childhood onset and absence of cardiac hypertrophy

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Cardioprotective effects of 70-kDa heat shock protein in transgenic mice

7 January 2021

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Compensatory mechanisms associated with the hyperdynamic function of phospholamban-deficient mouse hearts

7 January 2021

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Long-term expression of protein kinase C in adult mouse hearts improves postischemic recovery

7 January 2021

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Overexpression of the cardiac beta(2)-adrenergic receptor and expression of a beta-adrenergic receptor kinase-1 (betaARK1) inhibitor both increase myocardial contractility but have differential effects on susceptibility to ischemic injury

7 January 2021

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Male and female mice overexpressing the beta(2)-adrenergic receptor exhibit differences in ischemia/reperfusion injury: role of nitric oxide

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7 January 2021

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Mitochondrial tolerance to stress impaired in failing heart

7 January 2021

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Contribution of NO to ischemia-reperfusion injury in the saline-perfused heart: a study in endothelial NO synthase knockout mice

7 January 2021

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Acute inhibition of myoglobin impairs contractility and energy state of iNOS-overexpressing hearts

7 January 2021

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Cardiac-specific expression of heme oxygenase-1 protects against ischemia and reperfusion injury in transgenic mice

7 January 2021

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Knockout of Kir6.2 negates ischemic preconditioning-induced protection of myocardial energetics

7 January 2021

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MRI/MRS assessment of in vivo murine cardiac metabolism, morphology, and function at physiological heart rates

7 January 2021

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10.1016/J.YJMCC.2004.05.020

7 January 2021

Identifiers

DOI

1 reference

10 August 2017

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