(Q35879527)

English

Ligation of cytotoxic T lymphocyte antigen-4 to T cell receptor inhibits T cell activation and directs differentiation into Foxp3+ regulatory T cells

scientific article published on 15 February 2012

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Ligation of cytotoxic T lymphocyte antigen-4 to T cell receptor inhibits T cell activation and directs differentiation into Foxp3+ regulatory T cells (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

author name string

Jozsef Karman

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Ji-Lei Jiang

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Nathan Gumlaw

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Hongmei Zhao

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Juanita Campos-Rivera

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Jose Sancho

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Jinhua Zhang

7

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Canwen Jiang

8

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Seng H Cheng

9

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Yunxiang Zhu

10

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

15 February 2012

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

287

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

14

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

11098-11107

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Taming tissue-specific T cells: CTLA-4 reins in self-reactive T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

Dual function of CTLA-4 in regulatory T cells and conventional T cells to prevent multiorgan autoimmunity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

CTLA-4 suppresses the pathogenicity of self antigen-specific T cells by cell-intrinsic and cell-extrinsic mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

PD-L1 regulates the development, maintenance, and function of induced regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

Dominant role of antigen dose in CD4+Foxp3+ regulatory T cell induction and expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

The clinical utility of inhibiting CD28-mediated costimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

Regulating the regulators: costimulatory signals control the homeostasis and function of regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

CD4+ regulatory T cells require CTLA-4 for the maintenance of systemic tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

CTLA-4 control over Foxp3+ regulatory T cell function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

The AKT-mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

Inhibition of T cell activation and autoimmune diabetes using a B cell surface-linked CTLA-4 agonist.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

Targeted CTLA-4 engagement induces CD4+CD25+CTLA-4high T regulatory cells with target (allo)antigen specificity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

CD80 and CD86 C domains play an important role in receptor binding and co-stimulatory properties

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

Surface cytotoxic T lymphocyte-associated antigen 4 partitions within lipid rafts and relocates to the immunological synapse under conditions of inhibition of T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

Inhibition of CTLA-4 function by the regulatory subunit of serine/threonine phosphatase 2A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

Development and applications of surface-linked single chain antibodies against T-cell antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

The CD28 and CTLA-4 receptors associate with the serine/threonine phosphatase PP2A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

Blockade of T cell activation using a surface-linked single-chain antibody to CTLA-4 (CD152).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

The immunological synapse: a molecular machine controlling T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

Engagement of cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) induces transforming growth factor beta (TGF-beta) production by murine CD4(+) T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

CTLA-4-B7 interaction is sufficient to costimulate T cell clonal expansion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

CTLA-4: a negative regulator of autoimmune disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

CTLA-4 ligation blocks CD28-dependent T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

CTLA-4 engagement inhibits IL-2 accumulation and cell cycle progression upon activation of resting T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

CTLA-4 can function as a negative regulator of T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

LAG-3, a novel lymphocyte activation gene closely related to CD4

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

11 July 2018

CTLA-4 suppresses proximal TCR signaling in resting human CD4(+) T cells by inhibiting ZAP-70 Tyr(319) phosphorylation: a potential role for tyrosine phosphatases

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283705

21 January 2018

B7-1 and B7-2 selectively recruit CTLA-4 and CD28 to the immunological synapse

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283705

21 January 2018

Differential expression of CTLA-4 among T cell subsets

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283705

21 January 2018

CTLA4Ig: bridging the basic immunology with clinical application

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283705

21 January 2018

Immunosuppression induced by immature dendritic cells is mediated by TGF-beta/IL-10 double-positive CD4+ regulatory T cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283705

21 January 2018

Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283705

21 January 2018

Distinct roles of CTLA-4 and TGF-beta in CD4+CD25+ regulatory T cell function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.283705

21 January 2018

Ctla-4 controls regulatory T cell peripheral homeostasis and is required for suppression of pancreatic islet autoimmunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

24 September 2018

Enhanced engagement of CTLA-4 induces antigen-specific CD4+CD25+Foxp3+ and CD4+CD25- TGF-beta 1+ adaptive regulatory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

24 September 2018

The role of CTLA-4 in induction and maintenance of peripheral T cell tolerance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

24 September 2018

Targeted delivery of anti-CTLA-4 antibody downregulates T cell function in vitro and in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

24 September 2018

CTLA-4 regulates tolerance induction and T cell differentiation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

24 September 2018

CTLA-4 ligation delivers a unique signal to resting human CD4 T cells that inhibits interleukin-2 secretion but allows Bcl-X(L) induction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

24 September 2018

Human B7-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3322849

24 September 2018

Regulatory T cells dynamically control the primary immune response to foreign antigen

1 reference

https://pubmed.ncbi.nlm.nih.gov/22337882

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A kinetic and dynamic analysis of Foxp3 induced in T cells by TGF-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/22337882

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M111.283705

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

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