(Q35884806)

English

Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein

scientific article published in November 1996

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdr 1a P-glycoprotein (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

0 references

author name string

Mayer U

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Wagenaar E

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Beijnen JH

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Smit JW

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Meijer DK

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

van Asperen J

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Borst P

7

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Schinkel AH

8

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

language of work or name

0 references

publication date

1 November 1996

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

British Journal of Pharmacology

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

119

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

1038-1044

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Altered pharmacokinetics of vinblastine in Mdr1a P-glycoprotein-deficient Mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Digoxin-cyclosporin A interaction: modulation of the multidrug transporter P-glycoprotein in the kidney

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Biochemistry of multidrug resistance mediated by the multidrug transporter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Absence of the mdr1a P-Glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone, digoxin, and cyclosporin A.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Renal and gastrointestinal excretion of ouabain in dog and man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Quantitative analysis of digoxin, 4'''-acetyldigoxin and 4'''-methyldigoxin and their metabolites in bile and urine of rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Correlation of MDR1 gene expression with chemotherapy in neuroblastoma.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Chemotherapy for brain metastases: recent developments and clinical considerations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Pharmacology of drugs that alter multidrug resistance in cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

The clinical relevance of multidrug resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Multidrug resistance (mdr1) gene expression in adult acute leukemias: correlations with treatment outcome and in vitro drug sensitivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Resistance modification by PSC-833, a novel non-immunosuppressive cyclosporin A

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Cyclosporin and quinidine inhibition of renal digoxin excretion: evidence for luminal secretion of digoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Concentration of cardiac glycosides in the heart and brain (author's transl)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Digoxin-quinidine interaction Pharmacokinetic evaluation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Tissue Distribution and Elimination of Digoxin and Methyldigoxin After Single and Multiple Doses in Dogs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

27 July 2018

Role of P-glycoprotein in renal tubular secretion of digoxin in the isolated perfused rat kidney.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

24 September 2018

Multidrug resistance in lymphomas.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

24 September 2018

A phase III randomized study of oral verapamil as a chemosensitizer to reverse drug resistance in patients with refractory myeloma. A Southwest Oncology Group study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

24 September 2018

Clinical reversal of multidrug resistance.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

24 September 2018

Neurotoxicity of chemotherapeutic agents after blood-brain barrier modification: neuropathological studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

24 September 2018

Renal tubular secretion of digoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

24 September 2018

Pharmacokinetics of digoxin and its 4'''-acetyl- and methylderivates in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1915939

24 September 2018

ENTERAL RESORPTION, BILIARY EXCRETION AND ENTERO-HEPATIC CIRCULATION OF CARDIAC GLYCOSIDES IN RATS

1 reference

https://pubmed.ncbi.nlm.nih.gov/8922756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Detection of digitalis extracardiac effects in rat. II. Effect on intestines and blood vessels]

1 reference

https://pubmed.ncbi.nlm.nih.gov/8922756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The mechanism of the verapamil-digoxin interaction in renal tubular cells (LLC-PK1)

1 reference

https://pubmed.ncbi.nlm.nih.gov/8922756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evaluation of the enterohepatic circulation after 3 H-digoxin administration in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/8922756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P-glycoprotein--a marker of cancer-cell behavior

1 reference

https://pubmed.ncbi.nlm.nih.gov/8922756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[Intestinal secretion of cardiotonic steroids--studies on the mechanism of the absorption process]

1 reference

https://pubmed.ncbi.nlm.nih.gov/8922756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil

1 reference

https://pubmed.ncbi.nlm.nih.gov/8922756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Controlled trial of dexverapamil, a modulator of multidrug resistance, in lymphomas refractory to EPOCH chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/8922756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxicity of antineoplastic drugs

1 reference

https://pubmed.ncbi.nlm.nih.gov/8922756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of P-glycoprotein in high-grade osteosarcomas in relation to clinical outcome

1 reference

https://pubmed.ncbi.nlm.nih.gov/8922756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quinidine as a resistance modulator of epirubicin in advanced breast cancer: mature results of a placebo-controlled randomized trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/8922756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

THE METABOLISM OF DIGOXIN IN NORMAL SUBJECTS

1 reference

https://pubmed.ncbi.nlm.nih.gov/8922756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of the intestinal digoxin absorption and exsorption by quinidine

1 reference

https://pubmed.ncbi.nlm.nih.gov/8922756

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.1996.TB15775.X

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

0 references

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