(Q35887417)

English

Safety and immunogenicity of an investigational 4-component Staphylococcus aureus vaccine with or without AS03B adjuvant: Results of a randomized phase I trial

scientific article published in January 2015

In more languages

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Safety and immunogenicity of an investigational 4-component Staphylococcus aureus vaccine with or without AS03B adjuvant: Results of a randomized phase I trial (English)

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

phase I clinical trial

0 references

Staphylococcus aureus

1 reference

based on heuristic

inferred from title

author name string

Jack Levy

1

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Laurent Licini

2

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Edwige Haelterman

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Philippe Moris

4

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Pascal Lestrate

5

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Silvia Damaso

6

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Pascale Van Belle

7

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Dominique Boutriau

8

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

publication date

1 January 2015

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Human Vaccines & Immunotherapeutics

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

11

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

3

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

620-631

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

Efficacy profile of a bivalent Staphylococcus aureus glycoconjugated vaccine in adults on hemodialysis: Phase III randomized study

1 reference

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Role of antibodies in protection elicited by active vaccination with genetically inactivated alpha hemolysin in a mouse model of staphylococcus aureus skin and soft tissue infections

1 reference

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Adhesion, invasion and evasion: the many functions of the surface proteins of Staphylococcus aureus

1 reference

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Prevention of Staphylococcus aureus infections by glycoprotein vaccines synthesized in Escherichia coli

1 reference

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Safety, immunogenicity, and antibody persistence following an investigational Streptococcus pneumoniae and Haemophilus influenzae triple-protein vaccine in a phase 1 randomized controlled study in healthy adults.

1 reference

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1 reference

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Protein antigens increase the protective efficacy of a capsule-based vaccine against Staphylococcus aureus in a rat model of osteomyelitis.

1 reference

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National burden of invasive methicillin-resistant Staphylococcus aureus infections, United States, 2011.

1 reference

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Safety and immunogenicity of an AS01-adjuvanted varicella-zoster virus subunit candidate vaccine against herpes zoster in adults >=50 years of age.

1 reference

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Selection of an adjuvant for seasonal influenza vaccine in elderly people: modelling immunogenicity from a randomized trial

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Immunogenicity analysis of Staphylococcus aureus clumping factor A genetic variants

1 reference

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Long-term persistence of humoral and cellular immune responses induced by an AS03A-adjuvanted H1N1 2009 influenza vaccine: an open-label, randomized study in adults aged 18-60 years and older

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Effect of an investigational vaccine for preventing Staphylococcus aureus infections after cardiothoracic surgery: a randomized trial

1 reference

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AS03-adjuvanted versus non-adjuvanted inactivated trivalent influenza vaccine against seasonal influenza in elderly people: a phase 3 randomised trial

1 reference

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Staphylococcus aureus phenol-soluble modulin peptides modulate dendritic cell functions and increase in vitro priming of regulatory T cells.

1 reference

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A serologic correlate of protective immunity against community-onset Staphylococcus aureus infection.

1 reference

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Meningococcal quadrivalent (serogroups A, C, W135 and Y) tetanus toxoid conjugate vaccine (Nimenrix™).

1 reference

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Control of adaptive immune responses by Staphylococcus aureus through IL-10, PD-L1, and TLR2

1 reference

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Development of a multicomponent Staphylococcus aureus vaccine designed to counter multiple bacterial virulence factors

1 reference

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Inferring reasons for the failure of Staphylococcus aureus vaccines in clinical trials

1 reference

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A recombinant clumping factor A-containing vaccine induces functional antibodies to Staphylococcus aureus that are not observed after natural exposure

1 reference

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11 July 2018

Novel structurally designed vaccine for S. aureus α-hemolysin: protection against bacteremia and pneumonia

1 reference

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Molecular mechanisms of the immunological abnormalities in hyper-IgE syndrome

1 reference

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Progress toward a Staphylococcus aureus vaccine

1 reference

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11 July 2018

Is there a future for a Staphylococcus aureus vaccine?

1 reference

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11 July 2018

Recurrent infections and immune evasion strategies of Staphylococcus aureus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4514337

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Human monocytes promote Th1 and Th17 responses to Streptococcus pneumoniae

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Immunity against Staphylococcus aureus cutaneous infections

1 reference

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Comparative effects of carrier proteins on vaccine-induced immune response

1 reference

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Staphylococcus aureus biofilms prevent macrophage phagocytosis and attenuate inflammation in vivo

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The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota

1 reference

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11 July 2018

Effect on cellular and humoral immune responses of the AS03 adjuvant system in an A/H1N1/2009 influenza virus vaccine administered to adults during two randomized controlled trials.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4514337

11 July 2018

Adjuvant System AS03 containing α-tocopherol modulates innate immune response and leads to improved adaptive immunity.

1 reference

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Staphylococcal alpha-toxin is a strong inducer of interleukin-17 in humans

1 reference

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11 July 2018

H5N1 influenza vaccine formulated with AS03 A induces strong cross-reactive and polyfunctional CD4 T-cell responses.

1 reference

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Pneumolysin activates the NLRP3 inflammasome and promotes proinflammatory cytokines independently of TLR4.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4514337

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A new view on development of a Staphylococcus aureus vaccine: insights from mice and men.

1 reference

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Evaluation of clumping factor A binding region A in a subunit vaccine against Staphylococcus aureus-induced mastitis in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4514337

11 July 2018

Targeting of alpha-hemolysin by active or passive immunization decreases severity of USA300 skin infection in a mouse model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4514337

11 July 2018

Role of interleukin-17A in cell-mediated protection against Staphylococcus aureus infection in mice immunized with the fibrinogen-binding domain of clumping factor A.

1 reference

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Innate IL-17-producing cells: the sentinels of the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4514337

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Safety and cross-reactive immunogenicity of candidate AS03-adjuvanted prepandemic H5N1 influenza vaccines: a randomized controlled phase 1/2 trial in adults

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4514337

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Th1-Th17 cells mediate protective adaptive immunity against Staphylococcus aureus and Candida albicans infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4514337

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10-valent pneumococcal nontypeable Haemophilus influenzae PD conjugate vaccine: Synflorix.

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CCR6 is required for IL-23-induced psoriasis-like inflammation in mice

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Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Vaccine protection against Staphylococcus aureus pneumonia

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1 reference

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1 reference

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Emergence and resurgence of meticillin-resistant Staphylococcus aureus as a public-health threat

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Immune evasion by staphylococci

1 reference

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Roles for fibrinogen, immunoglobulin and complement in platelet activation promoted by Staphylococcus aureus clumping factor A.

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Staphylococcus aureus strains that express serotype 5 or serotype 8 capsular polysaccharides differ in virulence

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Staphylococcus aureus capsular polysaccharides

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Use of a Staphylococcus aureus conjugate vaccine in patients receiving hemodialysis.

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Staphylococcus aureus infections

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Alpha-toxin of Staphylococcus aureus

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Lower antibody levels to Staphylococcus aureus exotoxins are associated with sepsis in hospitalized adults with invasive S. aureus infections.

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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https://pubmed.ncbi.nlm.nih.gov/25715157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vaccination as infection control: a pilot study to determine the impact of Staphylococcus aureus vaccination on nasal carriage

1 reference

https://pubmed.ncbi.nlm.nih.gov/25715157

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1080/21645515.2015.1011021

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

10 August 2017

ResearchGate publication ID

0 references

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