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Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells.
scientific article published on 21 March 2012
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scholarly article
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Europe PubMed Central
PMC publication ID
3325864
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22436134%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
title
Downregulation of HuR as a new mechanism of doxorubicin resistance in breast cancer cells
(English)
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stated in
Europe PubMed Central
PMC publication ID
3325864
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22436134%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
main subject
doxorubicin
1 reference
based on heuristic
inferred from title
breast cancer
1 reference
based on heuristic
inferred from title
author
Elisa Latorre
series ordinal
1
1 reference
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Europe PubMed Central
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3325864
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22436134%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
Toma Tebaldi
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2
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Europe PubMed Central
PMC publication ID
3325864
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22436134%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
Gabriella Viero
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3
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Europe PubMed Central
PMC publication ID
3325864
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22436134%20AND%20SRC:MED&resulttype=core&format=json
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26 January 2020
Alessandro Quattrone
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5
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3325864
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retrieved
26 January 2020
Alessandro Provenzani
series ordinal
6
1 reference
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Europe PubMed Central
PMC publication ID
3325864
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22436134%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
author name string
Antonino Maria Spartà
series ordinal
4
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Europe PubMed Central
PMC publication ID
3325864
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26 January 2020
publication date
21 March 2012
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Europe PubMed Central
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3325864
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retrieved
26 January 2020
published in
Molecular Cancer
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Europe PubMed Central
PMC publication ID
3325864
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22436134%20AND%20SRC:MED&resulttype=core&format=json
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26 January 2020
volume
11
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Europe PubMed Central
PMC publication ID
3325864
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retrieved
26 January 2020
page(s)
13
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Europe PubMed Central
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3325864
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22436134%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
exact match
https://scigraph.springernature.com/pub.10.1186/1476-4598-11-13
0 references
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Amelioration of doxorubicin-induced cardiotoxicity by an anticancer-antioxidant dual-function compound, HO-3867
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Translational control of TOP2A influences doxorubicin efficacy
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The RNA-binding protein HuR promotes glioma growth and treatment resistance.
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In vitro selected RNA aptamer recognizing glutathione induces ROS mediated apoptosis in the human breast cancer cell line MCF 7.
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11 July 2018
Regulation of HuR by DNA Damage Response Kinases
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Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line
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11 July 2018
Protein kinase RNA/FADD/caspase-8 pathway mediates the proapoptotic activity of the RNA-binding protein human antigen R (HuR).
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11 July 2018
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Essential role of the RNA-binding protein HuR in progenitor cell survival in mice.
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Mechanisms of chemotherapeutic drug resistance in cancer therapy--a quick review
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11 July 2018
Understanding the causes of multidrug resistance in cancer: a comparison of doxorubicin and sunitinib
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11 July 2018
The role of HuR in gemcitabine efficacy in pancreatic cancer: HuR Up-regulates the expression of the gemcitabine metabolizing enzyme deoxycytidine kinase.
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Targeting DNA topoisomerase II in cancer chemotherapy
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11 July 2018
The RNA-binding protein Elavl1/HuR is essential for placental branching morphogenesis and embryonic development
1 reference
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11 July 2018
The RNA-binding protein HuR regulates DNA methylation through stabilization of DNMT3b mRNA.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources
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PubMed Central
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11 July 2018
Transterm: a database to aid the analysis of regulatory sequences in mRNAs
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11 July 2018
Phosphorylated HuR shuttles in cycles
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer
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11 July 2018
Cytoplasmic accumulation of the RNA binding protein HuR is central to tamoxifen resistance in estrogen receptor positive breast cancer cells.
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reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Post-transcriptional gene regulation by HuR promotes a more tumorigenic phenotype
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Signalling pathways regulating nucleo-cytoplasmic shuttling of the mRNA-binding protein HuR.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Topoisomerase levels determine chemotherapy responsein vitroandin vivo
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Posttranslational modification of the AU-rich element binding protein HuR by protein kinase Cdelta elicits angiotensin II-induced stabilization and nuclear export of cyclooxygenase 2 mRNA
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Caspase-mediated cleavage of HuR in the cytoplasm contributes to pp32/PHAP-I regulation of apoptosis
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Rottlerin: an inappropriate and ineffective inhibitor of PKCdelta
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Identification and mechanistic characterization of low-molecular-weight inhibitors for HuR
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
FRET-detectable interactions between the ARE binding proteins, HuR and p37AUF1.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Posttranscriptional orchestration of an anti-apoptotic program by HuR.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Involvement of transportin 2-mediated HuR import in muscle cell differentiation
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Phosphorylation of HuR by Chk2 regulates SIRT1 expression
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
HuR: post-transcriptional paths to malignancy.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Expression of the ELAV-like protein HuR in human colon cancer: association with tumor stage and cyclooxygenase-2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Translational control of cytochrome c by RNA-binding proteins TIA-1 and HuR
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Antiapoptotic function of RNA-binding protein HuR effected through prothymosin alpha
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Identification of a target RNA motif for RNA-binding protein HuR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
retrieved
11 July 2018
Role of the RNA-binding protein HuR in colon carcinogenesis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
DAVID: Database for Annotation, Visualization, and Integrated Discovery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
HuR regulates p21 mRNA stabilization by UV light
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
A multidrug resistance transporter from human MCF-7 breast cancer cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
retrieved
11 July 2018
ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Developmental expression of AUF1 and HuR, two c-myc mRNA binding proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
retrieved
11 July 2018
Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
retrieved
11 July 2018
Cloning and characterization of HuR, a ubiquitously expressed Elav-like protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Rottlerin, a novel protein kinase inhibitor
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Expression of a full-length cDNA for the human "MDR1" gene confers resistance to colchicine, doxorubicin, and vinblastine
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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11 July 2018
Transcriptome-wide analysis of regulatory interactions of the RNA-binding protein HuR.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
retrieved
24 September 2018
High-constitutive HuR phosphorylation at Ser 318 by PKC{delta} propagates tumor relevant functions in colon carcinoma cells.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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24 September 2018
Cytoplasmic HuR expression is a prognostic factor in invasive ductal breast carcinoma.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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24 September 2018
Cytoplasmic HuR expression correlates with poor outcome and with cyclooxygenase 2 expression in serous ovarian carcinoma.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3325864
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24 September 2018
Docosahexaenoic acid reverts resistance to UV-induced apoptosis in human keratinocytes: involvement of COX-2 and HuR
1 reference
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Crossref
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https://api.crossref.org/works/10.1186%2F1476-4598-11-13
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21 January 2018
Relationship between topoisomerase II level and chemosensitivity in human tumor cell lines
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22436134
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1186/1476-4598-11-13
1 reference
stated in
Europe PubMed Central
PMC publication ID
3325864
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22436134%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
Dimensions Publication ID
1016487425
0 references
PMC publication ID
3325864
1 reference
stated in
Europe PubMed Central
PMC publication ID
3325864
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22436134%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
PubMed publication ID
22436134
1 reference
stated in
Europe PubMed Central
PMC publication ID
3325864
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22436134%20AND%20SRC:MED&resulttype=core&format=json
retrieved
26 January 2020
ResearchGate publication ID
221902735
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