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Vpr of simian immunodeficiency virus of African green monkeys is required for replication in macaque macrophages and lymphocytes.
scientific article published in July 1997
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scholarly article
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Europe PubMed Central
PMC publication ID
191801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188633%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
title
Vpr of simian immunodeficiency virus of African green monkeys is required for replication in macaque macrophages and lymphocytes
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
191801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188633%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
main subject
Simian immunodeficiency virus
0 references
Macaca
0 references
author name string
Campbell BJ
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMC publication ID
191801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188633%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
Hirsch VM
series ordinal
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
191801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188633%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
language of work or name
English
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publication date
1 July 1997
1 reference
stated in
Europe PubMed Central
PMC publication ID
191801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188633%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
published in
Journal of Virology
1 reference
stated in
Europe PubMed Central
PMC publication ID
191801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188633%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
volume
71
1 reference
stated in
Europe PubMed Central
PMC publication ID
191801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188633%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
issue
7
1 reference
stated in
Europe PubMed Central
PMC publication ID
191801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188633%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
page(s)
5593-5602
1 reference
stated in
Europe PubMed Central
PMC publication ID
191801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188633%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
cites work
Conservation and host specificity of Vpr-mediated cell cycle arrest suggest a fundamental role in primate lentivirus evolution and biology.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Nuclear import and cell cycle arrest functions of the HIV-1 Vpr protein are encoded by two separate genes in HIV-2/SIV(SM).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Vpr-induced cell cycle arrest is conserved among primate lentiviruses.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Human immunodeficiency virus type 1 cell cycle control: Vpr is cytostatic and mediates G2 accumulation by a mechanism which differs from DNA damage checkpoint control.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Vpx association with mature core structures of HIV-2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Human immunodeficiency virus type 1 Vpr protein binds to the uracil DNA glycosylase DNA repair enzyme
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Induction of cell differentiation by human immunodeficiency virus 1 vpr.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Intracellular transport and virion incorporation of vpx requires interaction with other virus type-specific components.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Importance of vpr for infection of rhesus monkeys with simian immunodeficiency virus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: mutational analysis of a primary HIV-1 isolate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Extensive envelope heterogeneity of simian immunodeficiency virus in tissues from infected macaques
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cells
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Localization of the Vpx packaging signal within the C terminus of the human immunodeficiency virus type 2 Gag precursor protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Localization of viral protein X in simian immunodeficiency virus macaque strain and analysis of its packaging requirements
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Construction and in vitro properties of SIVmac mutants with deletions in "nonessential" genes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Human immunodeficiency virus Vpx is required for the early phase of replication in peripheral blood mononuclear cells
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Progression to AIDS in the absence of a gene for vpr or vpx.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Functional analysis of the vpx, vpr, and nef genes of simian immunodeficiency virus.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
HIV-1 infection of nondividing cells: C-terminal tyrosine phosphorylation of the viral matrix protein is a key regulator
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Induction of AIDS by simian immunodeficiency virus from an African green monkey: species-specific variation in pathogenicity correlates with the extent of in vivo replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Extracellular Vpr protein increases cellular permissiveness to human immunodeficiency virus replication and reactivates virus from latency.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infection
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
The glucocorticoid receptor type II complex is a target of the HIV-1 vpr gene product
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
Identification of a nef allele that causes lymphocyte activation and acute disease in macaque monkeys
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
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11 July 2018
HIV accessory proteins: leading roles for the supporting cast.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
vpr deletion mutant of simian immunodeficiency virus induces AIDS in rhesus monkeys
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Interaction of Virion Protein Vpr of Human Immunodeficiency Virus Type 1 with Cellular Transcription Factor Sp1 and trans-Activation of Viral Long Terminal Repeat
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Functional analysis of HIV-1 Vpr: identification of determinants essential for subcellular localization.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Characterization of a CD4-expressing macaque cell line that can detect virus after a single replication cycle and can be infected by diverse simian immunodeficiency virus isolates
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Mutagenic analysis of human immunodeficiency virus type 1 Vpr: role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
A leucine triplet repeat sequence (LXX)4 in p6gag is important for Vpr incorporation into human immunodeficiency virus type 1 particles
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G2 phase of the cell cycle by inhibiting p34cdc2 activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
VPX mutants of HIV-2 are infectious in established cell lines but display a severe defect in peripheral blood lymphocytes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Analysis of the function of viral protein X (VPX) of HIV-2.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Identification of HIV-1 vpr product and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Dispensable role of the human immunodeficiency virus type 2 Vpx protein in viral replication
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Importance of the nef gene for maintenance of high virus loads and for development of AIDS
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
The vpx gene of simian immunodeficiency virus facilitates efficient viral replication in fresh lymphocytes and macrophage
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Active nuclear import of human immunodeficiency virus type 1 preintegration complexes
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Dual regulation of silent and productive infection in monocytes by distinct human immunodeficiency virus type 1 determinants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Evolution of the primate lentiviruses: evidence from vpx and vpr
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
11 July 2018
Gene acquisition in HIV and SIV
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=191801
retrieved
14 November 2018
Identifiers
DOI
10.1128/JVI.71.7.5593-5602.1997
0 references
PMC publication ID
191801
1 reference
stated in
Europe PubMed Central
PMC publication ID
191801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188633%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
PubMed publication ID
9188633
1 reference
stated in
Europe PubMed Central
PMC publication ID
191801
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9188633%20AND%20SRC:MED&resulttype=core&format=json
retrieved
3 November 2019
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