(Q35891607)

English

Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2rγ null mice is enhanced by transgenic expression of membrane-bound human SCF.

scientific article published on 12 January 2012

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scholarly article

1 reference

Europe PubMed Central

11 August 2017

Engraftment of human HSCs in nonirradiated newborn NOD-scid IL2rγ null mice is enhanced by transgenic expression of membrane-bound human SCF. (English)

1 reference

Europe PubMed Central

11 August 2017

author name string

Michael A Brehm

1

1 reference

Europe PubMed Central

11 August 2017

Waldemar J Racki

2

1 reference

Europe PubMed Central

11 August 2017

Jean Leif

3

1 reference

Europe PubMed Central

11 August 2017

Lisa Burzenski

4

1 reference

Europe PubMed Central

11 August 2017

Vishnu Hosur

5

1 reference

Europe PubMed Central

11 August 2017

Amber Wetmore

6

1 reference

Europe PubMed Central

11 August 2017

Bruce Gott

7

1 reference

Europe PubMed Central

11 August 2017

Mary Herlihy

8

1 reference

Europe PubMed Central

11 August 2017

Ronald Ignotz

9

1 reference

Europe PubMed Central

11 August 2017

Raymond Dunn

10

1 reference

Europe PubMed Central

11 August 2017

Leonard D Shultz

11

1 reference

Europe PubMed Central

11 August 2017

Dale L Greiner

12

1 reference

Europe PubMed Central

11 August 2017

language of work or name

0 references

publication date

12 January 2012

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

119

1 reference

Europe PubMed Central

11 August 2017

2778-2788

1 reference

Europe PubMed Central

11 August 2017

12

1 reference

Europe PubMed Central

11 August 2017

Development of human CD4+FoxP3+ regulatory T cells in human stem cell factor-, granulocyte-macrophage colony-stimulating factor-, and interleukin-3-expressing NOD-SCID IL2Rγ(null) humanized mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Human immune system development and rejection of human islet allografts in spontaneously diabetic NOD-Rag1null IL2rgammanull Ins2Akita mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

NOD-scid IL2rgamma(null) mouse model of human skin transplantation and allograft rejection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Parameters for establishing humanized mouse models to study human immunity: analysis of human hematopoietic stem cell engraftment in three immunodeficient strains of mice bearing the IL2rgamma(null) mutation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Radiation damage increases Purkinje neuron heterokaryons in neonatal cerebellum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

IL-15 trans-presentation promotes human NK cell development and differentiation in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Creation of "humanized" mice to study human immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

NOD/Shi-scid IL2rgamma(null) (NOG) mice more appropriate for humanized mouse models.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Humanized mice in translational biomedical research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Mechanisms of anemia in SHP-1 protein tyrosine phosphatase-deficient "viable motheaten" mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

SCID mouse models of human stem cell engraftment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Stem cell factor and hematopoiesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

The DNA damage response in DNA-dependent protein kinase-deficient SCID mouse cells: replication protein A hyperphosphorylation and p53 induction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Identification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Irradiation injury to the developing nervous system: mechanisms of neuronal injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Gene for the catalytic subunit of mouse DNA-dependent protein kinase maps to the scid locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

A severe combined immunodeficiency mutation in the mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

The proto-oncogene c-kit encoding a transmembrane tyrosine kinase receptor maps to the mouse W locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Primary structure and functional expression of rat and human stem cell factor DNAs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Alternate splicing of mRNAs encoding human mast cell growth factor and localization of the gene to chromosome 12q22-q24

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Transmembrane form of the kit ligand growth factor is determined by alternative splicing and is missing in the Sld mutant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

RAG-1-deficient mice have no mature B and T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

RAG-2-deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Differential expression and processing of two cell associated forms of the kit-ligand: KL-1 and KL-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

11 July 2018

Non-obese diabetic-recombination activating gene-1 (NOD-Rag1 null) interleukin (IL)-2 receptor common gamma chain (IL2r gamma null) null mice: a radioresistant model for human lymphohaematopoietic engraftment.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

24 September 2018

HLA and KIR polymorphisms affect NK-cell anti-tumor activity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

24 September 2018

Human-Hemato-Lymphoid-System Mice: Opportunities and Challenges

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327456

14 November 2018

THE CELLULAR BASIS OF DIFFERENTIAL RADIOSENSITIVITY OF NORMAL AND GENETICALLY ANEMIC MICE

1 reference

https://pubmed.ncbi.nlm.nih.gov/22246028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD47 is a ligand for rat macrophage membrane signal regulatory protein SIRP (OX41) and human SIRPalpha 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/22246028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intra-bone marrow transplantation of human CD34(+) cells into NOD/LtSz-scid IL-2rgamma(null) mice permits multilineage engraftment without previous irradiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22246028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional CD5+ B cells develop predominantly in the spleen of NOD/SCID/gammac(null) (NOG) mice transplanted either with human umbilical cord blood, bone marrow, or mobilized peripheral blood CD34+ cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22246028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multi-level effects of flt3 ligand on human hematopoiesis: expansion of putative stem cells and proliferation of granulomonocytic progenitors/monocytic precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22246028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved engraftment of human acute myeloid leukemia progenitor cells in beta 2-microglobulin-deficient NOD/SCID mice and in NOD/SCID mice transgenic for human growth factors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22246028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of human stem cell factor impairs melanocyte, mast cell, and thymocyte development: a role for receptor tyrosine kinase-mediated mitogen activated protein kinase activation in cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22246028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The scid mutation in mice causes a general defect in DNA repair

1 reference

https://pubmed.ncbi.nlm.nih.gov/22246028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xenogeneic expression of human stem cell factor in transgenic mice mimics codominant c-kit mutations

1 reference

https://pubmed.ncbi.nlm.nih.gov/22246028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Acute radiosensitivity in mice of differing W genotype

1 reference

https://pubmed.ncbi.nlm.nih.gov/22246028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NOD/SCID mice engineered to express human IL-3, GM-CSF and Steel factor constitutively mobilize engrafted human progenitors and compromise human stem cell regeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/22246028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transfer of a functional human immune system to mice with severe combined immunodeficiency

1 reference

https://pubmed.ncbi.nlm.nih.gov/22246028

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1182/BLOOD-2011-05-353243

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

1 reference

Europe PubMed Central

11 August 2017

ResearchGate publication ID

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